DK0777482T3 - Kombinationspræparat til behandling af immunsygdomme - Google Patents
Kombinationspræparat til behandling af immunsygdommeInfo
- Publication number
- DK0777482T3 DK0777482T3 DK95930441T DK95930441T DK0777482T3 DK 0777482 T3 DK0777482 T3 DK 0777482T3 DK 95930441 T DK95930441 T DK 95930441T DK 95930441 T DK95930441 T DK 95930441T DK 0777482 T3 DK0777482 T3 DK 0777482T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- combination preparation
- immune disorders
- compound
- phosphodiesterase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4430128A DE4430128A1 (de) | 1994-08-25 | 1994-08-25 | Kombinationspräparat mit immunsuppressiven, kardiovaskulären und cerebralen Wirkungen |
PCT/EP1995/003125 WO1996005838A2 (de) | 1994-08-25 | 1995-08-07 | Kombinationspräparat zur anwendung bei immunologischen erkrankungen |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0777482T3 true DK0777482T3 (da) | 2002-02-18 |
Family
ID=6526515
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95930441T DK0777482T3 (da) | 1994-08-25 | 1995-08-07 | Kombinationspræparat til behandling af immunsygdomme |
Country Status (12)
Country | Link |
---|---|
US (2) | US5990103A (da) |
EP (1) | EP0777482B1 (da) |
JP (1) | JPH10504550A (da) |
AT (1) | ATE208620T1 (da) |
AU (1) | AU697311B2 (da) |
DE (2) | DE4430128A1 (da) |
DK (1) | DK0777482T3 (da) |
ES (1) | ES2162937T3 (da) |
FI (1) | FI970747A (da) |
MX (1) | MX9701385A (da) |
PT (1) | PT777482E (da) |
WO (1) | WO1996005838A2 (da) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6294350B1 (en) * | 1997-06-05 | 2001-09-25 | Dalhousie University | Methods for treating fibroproliferative diseases |
WO2000009133A1 (en) * | 1998-08-10 | 2000-02-24 | Asahi Kasei Kogyo Kabushiki Kaisha | Sustained release oral preparations of fasudil hydrochloride |
US6368815B1 (en) * | 1999-03-29 | 2002-04-09 | Warner-Lambert Company | Screening of molecules that inhibit human phosphodiesterase 4A produced by non-recombinant cell lines |
NZ514158A (en) * | 1999-03-31 | 2000-03-29 | Vernalis Ltd | Derivatives of pyrimido[6,1-a]isoquinolin-4-one |
AU2001259691B2 (en) | 2000-05-12 | 2006-02-16 | Genzyme Corporation | Modulators of TNF-alpha signaling |
US7470718B2 (en) * | 2000-10-03 | 2008-12-30 | Albert Einstein College Of Medicine Of Yeshiva University | Method for treating a demyelinating condition |
US20040242565A1 (en) * | 2001-09-11 | 2004-12-02 | Yoshinori Toshima | Medicinal composition for prevention of or treatment for cerebrovascular disorder and cardiopathy |
CA2461946C (en) * | 2001-10-05 | 2010-01-12 | Combinatorx, Incorporated | Combinations for the treatment of immunoinflammatory disorders |
DE10226420A1 (de) * | 2002-06-13 | 2004-01-15 | Eucro European Contract Research Gmbh & Co Kg | Verfahren zur Behandlung der Artherosklerose |
WO2004037183A2 (en) * | 2002-10-22 | 2004-05-06 | Harbor-Ucla Research And Education Institute | Phosphodiester inhibitors and nitric oxide modulators for treating peyronie’s disease, arteriosclerosis and other fibrotic diseases |
US8133903B2 (en) * | 2003-10-21 | 2012-03-13 | Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center | Methods of use of inhibitors of phosphodiesterases and modulators of nitric oxide, reactive oxygen species, and metalloproteinases in the treatment of peyronie's disease, arteriosclerosis and other fibrotic diseases |
DE60335652D1 (de) * | 2002-11-21 | 2011-02-17 | Genzyme Corp | Verwendung eines diamidderivats zur verhinderung der chronischen transplantatabstossung |
DK1562571T3 (da) * | 2002-11-21 | 2011-12-05 | Genzyme Corp | Kombination af et diamidderivat og immunsuppressive midler til hæmning af transplantatafstødning |
US20040147534A1 (en) * | 2003-01-23 | 2004-07-29 | Foote Mary Ann | Topical composition and method for treating occlusive wounds |
US20040241234A1 (en) * | 2003-06-02 | 2004-12-02 | Alpharma, Inc. | Controlled release press-coated formulations of water-soluble active agents |
TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
WO2006054536A1 (ja) * | 2004-11-16 | 2006-05-26 | Nippon Shinyaku Co., Ltd. | 尿路結石症治療剤 |
US7767710B2 (en) | 2005-05-25 | 2010-08-03 | Calosyn Pharma, Inc. | Method for treating osteoarthritis |
US20060269579A1 (en) * | 2005-05-25 | 2006-11-30 | Musculoskeletal Research Llc | Compositions for treating osteoarthritis |
WO2007139753A2 (en) * | 2006-05-22 | 2007-12-06 | Combinatorx, Incorporated | Methods and compositions for the treatment of diseases or conditions associated with increased c-reactive protein, interleukin-6, or interferon-gamma levels |
CA2737131A1 (en) * | 2007-09-19 | 2009-03-26 | Zalicus Inc. | Therapeutic regimens for the treatment of immunoinflammatory disorders |
WO2009042854A1 (en) * | 2007-09-26 | 2009-04-02 | Musculoskeletal Research Llc | Ion-channel regulator compositions and methods of using same |
MX2010006724A (es) * | 2007-12-17 | 2010-09-07 | Combinatorx Inc | Regimenes terapeuticos para el tratamiento de desordenes inmunoinflamatorios. |
MX2010009300A (es) | 2008-02-29 | 2010-11-05 | Concert Pharmaceuticals Inc | Derivados de xantina substituidos. |
US20110053961A1 (en) | 2009-02-27 | 2011-03-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
WO2013013052A1 (en) | 2011-07-19 | 2013-01-24 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
IN2014DN08443A (da) | 2012-04-13 | 2015-05-08 | Concert Pharmaceuticals Inc | |
CA2981791A1 (en) | 2014-04-18 | 2015-10-22 | Concert Pharmaceuticals, Inc. | Methods of treating hyperglycemia |
JP2022531154A (ja) * | 2019-04-30 | 2022-07-06 | ジェネロス バイオファーマ リミテッド | 炎症により引き起こされる自己免疫性皮膚疾患を治療するための化合物及びその使用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU601695B2 (en) * | 1985-07-02 | 1990-09-20 | Key Pharmaceuticals, Inc. | Method and composition for the treatment of chronic obstructive pulmonary disease |
DE3604149A1 (de) * | 1986-02-10 | 1987-08-13 | Rentschler Arzneimittel | Arzneimittelkombination |
IL100195A0 (en) * | 1990-11-30 | 1992-08-18 | Hoechst Roussel Pharma | Use of xanthines for the preparation of a medicament having immuno suppressing activity |
EP0493682A3 (en) * | 1990-11-30 | 1992-11-19 | Hoechst-Roussel Pharmaceuticals Incorporated | Use of xanthines for the preparation of a medicament effective for inhibiting the effects of allograft reaction in humans |
IL99368A (en) * | 1991-09-02 | 1996-01-19 | Teva Pharma | Preparations for the treatment of psoriasis and atopic dermatitis, which contain the result of xanthine |
US5190972A (en) * | 1992-01-27 | 1993-03-02 | The University Of Melbourne | Method of combatting cyclosporine organ toxicity with prostaglandin analogs |
CA2112239C (en) * | 1992-03-04 | 2000-05-09 | James A. Bianco | Enantiomeric hydroxylated xanthine compounds |
WO1993023082A1 (en) * | 1992-05-13 | 1993-11-25 | Alcon Laboratories, Inc. | Topical ophthalmic compositions comprising a combination of calcium antagonists with known antiglaucoma agents |
US5670506A (en) * | 1993-04-05 | 1997-09-23 | Cell Therapeutics, Inc. | Halogen, isothiocyanate or azide substituted xanthines |
-
1994
- 1994-08-25 DE DE4430128A patent/DE4430128A1/de not_active Withdrawn
-
1995
- 1995-08-07 PT PT95930441T patent/PT777482E/pt unknown
- 1995-08-07 JP JP8507740A patent/JPH10504550A/ja not_active Abandoned
- 1995-08-07 US US08/793,417 patent/US5990103A/en not_active Expired - Fee Related
- 1995-08-07 MX MX9701385A patent/MX9701385A/es not_active Application Discontinuation
- 1995-08-07 DK DK95930441T patent/DK0777482T3/da active
- 1995-08-07 WO PCT/EP1995/003125 patent/WO1996005838A2/de active IP Right Grant
- 1995-08-07 AT AT95930441T patent/ATE208620T1/de not_active IP Right Cessation
- 1995-08-07 EP EP95930441A patent/EP0777482B1/de not_active Expired - Lifetime
- 1995-08-07 ES ES95930441T patent/ES2162937T3/es not_active Expired - Lifetime
- 1995-08-07 AU AU33829/95A patent/AU697311B2/en not_active Ceased
- 1995-08-07 DE DE59509848T patent/DE59509848D1/de not_active Expired - Fee Related
-
1997
- 1997-02-21 FI FI970747A patent/FI970747A/fi not_active Application Discontinuation
-
1999
- 1999-07-20 US US09/357,230 patent/US6337325B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE208620T1 (de) | 2001-11-15 |
DE59509848D1 (de) | 2001-12-20 |
EP0777482B1 (de) | 2001-11-14 |
MX9701385A (es) | 1997-05-31 |
JPH10504550A (ja) | 1998-05-06 |
US5990103A (en) | 1999-11-23 |
PT777482E (pt) | 2002-04-29 |
EP0777482A1 (de) | 1997-06-11 |
FI970747A0 (fi) | 1997-02-21 |
WO1996005838A2 (de) | 1996-02-29 |
FI970747A (fi) | 1997-02-21 |
ES2162937T3 (es) | 2002-01-16 |
WO1996005838A3 (de) | 1996-04-11 |
AU697311B2 (en) | 1998-10-01 |
US6337325B1 (en) | 2002-01-08 |
AU3382995A (en) | 1996-03-14 |
DE4430128A1 (de) | 1996-02-29 |
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