DK0768890T3 - Metoder til modulering af T-cellereaktioner ved manipulation af en fælles cytokinreceptor-gamma-kæde - Google Patents

Metoder til modulering af T-cellereaktioner ved manipulation af en fælles cytokinreceptor-gamma-kæde

Info

Publication number
DK0768890T3
DK0768890T3 DK95924766T DK95924766T DK0768890T3 DK 0768890 T3 DK0768890 T3 DK 0768890T3 DK 95924766 T DK95924766 T DK 95924766T DK 95924766 T DK95924766 T DK 95924766T DK 0768890 T3 DK0768890 T3 DK 0768890T3
Authority
DK
Denmark
Prior art keywords
gamma chain
receptor
methods
cytokine receptor
interleukin
Prior art date
Application number
DK95924766T
Other languages
Danish (da)
English (en)
Inventor
Lee M Nadler
Vassiliki A Boussiotis
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Application granted granted Critical
Publication of DK0768890T3 publication Critical patent/DK0768890T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2026—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2046—IL-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK95924766T 1994-07-01 1995-06-30 Metoder til modulering af T-cellereaktioner ved manipulation af en fælles cytokinreceptor-gamma-kæde DK0768890T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/270,152 US6576236B1 (en) 1994-07-01 1994-07-01 Methods for stimulating T cell responses by manipulating a common cytokine receptor γ chain
PCT/US1995/008320 WO1996001122A1 (en) 1994-07-01 1995-06-30 Methods for modulating t cell responses by manipulating a common cytokine receptor gamma chain

Publications (1)

Publication Number Publication Date
DK0768890T3 true DK0768890T3 (da) 2008-06-09

Family

ID=23030131

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95924766T DK0768890T3 (da) 1994-07-01 1995-06-30 Metoder til modulering af T-cellereaktioner ved manipulation af en fælles cytokinreceptor-gamma-kæde

Country Status (10)

Country Link
US (2) US6576236B1 (de)
EP (2) EP1958966A2 (de)
JP (2) JPH10502372A (de)
AT (1) ATE386537T1 (de)
AU (1) AU2915295A (de)
CA (1) CA2194239A1 (de)
DE (1) DE69535713T2 (de)
DK (1) DK0768890T3 (de)
ES (1) ES2299174T3 (de)
WO (1) WO1996001122A1 (de)

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US7067318B2 (en) 1995-06-07 2006-06-27 The Regents Of The University Of Michigan Methods for transfecting T cells
US6692964B1 (en) 1995-05-04 2004-02-17 The United States Of America As Represented By The Secretary Of The Navy Methods for transfecting T cells
CA2220226C (en) * 1995-05-04 2008-10-21 Carl H. June Improved methods for transfecting t cells
DE59605711D1 (de) * 1995-10-11 2000-09-14 Arteva Tech Sarl Schwerentflammbare Sicherheitsgurte enthaltend phosphor-modifizierte Polyesterfasern
FR2745185B1 (fr) 1996-02-28 1998-05-15 Sanofi Sa Utilisation de l'il-7 dans le traitement des maladies auto-immunes, en particulier le diabete mellitus insulinodependant
JP2002516562A (ja) * 1996-03-04 2002-06-04 ターゲティッド ジェネティックス コーポレイション Ｔリンパ球のインビトロ増殖のための改変された迅速な拡大方法（「改変ｒｅｍ」）
US5807743A (en) * 1996-12-03 1998-09-15 Ribozyme Pharmaceuticals, Inc. Interleukin-2 receptor gamma-chain ribozymes
CA2279995A1 (en) * 1997-02-07 1998-08-13 Thomas Jefferson University Peptide mimetics of the cytokine receptor gamma chain
DE19721099C2 (de) 1997-05-20 1999-12-02 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten
DE19853487A1 (de) 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
US20020031787A1 (en) * 2000-02-04 2002-03-14 Maclaren Noel K. Compositions and methods for reducing autoimmunity
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AU2004269903B2 (en) 2003-09-09 2010-09-02 Biogen International Gmbh The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
SG170001A1 (en) * 2006-02-16 2011-04-29 Nascent Biolog Inc Methods for improving immune function and methods for prevention or treatment of disease in a mammalian subject
EP2680007A1 (de) 2007-02-08 2014-01-01 Biogen Idec MA Inc. Nrf2-screening-Assays sowie entsprechende Verfahren und Zusammensetzungen
JP2016523102A (ja) * 2013-06-24 2016-08-08 アントフロゲネシス コーポレーション Ｔ細胞を増殖させるための方法
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Also Published As

Publication number Publication date
JP2007112815A (ja) 2007-05-10
US20040037808A1 (en) 2004-02-26
EP0768890B1 (de) 2008-02-20
US6576236B1 (en) 2003-06-10
DE69535713T2 (de) 2009-03-19
CA2194239A1 (en) 1996-01-18
AU2915295A (en) 1996-01-25
EP1958966A2 (de) 2008-08-20
EP0768890A1 (de) 1997-04-23
ATE386537T1 (de) 2008-03-15
DE69535713D1 (de) 2008-04-03
JPH10502372A (ja) 1998-03-03
WO1996001122A1 (en) 1996-01-18
ES2299174T3 (es) 2008-05-16

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