DK0741724T3 - Neurobeskyttende chromanforbindelser - Google Patents

Neurobeskyttende chromanforbindelser

Info

Publication number
DK0741724T3
DK0741724T3 DK94931668T DK94931668T DK0741724T3 DK 0741724 T3 DK0741724 T3 DK 0741724T3 DK 94931668 T DK94931668 T DK 94931668T DK 94931668 T DK94931668 T DK 94931668T DK 0741724 T3 DK0741724 T3 DK 0741724T3
Authority
DK
Denmark
Prior art keywords
pct
neuroprotective
sec
date
chroman compounds
Prior art date
Application number
DK94931668T
Other languages
Danish (da)
English (en)
Inventor
Todd W Butler
Bertrand L Chenard
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0741724T3 publication Critical patent/DK0741724T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK94931668T 1994-01-31 1994-11-21 Neurobeskyttende chromanforbindelser DK0741724T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18947994A 1994-01-31 1994-01-31
PCT/IB1994/000365 WO1995020587A1 (en) 1994-01-31 1994-11-21 Neuroprotective chroman compounds

Publications (1)

Publication Number Publication Date
DK0741724T3 true DK0741724T3 (da) 1999-12-20

Family

ID=22697514

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94931668T DK0741724T3 (da) 1994-01-31 1994-11-21 Neurobeskyttende chromanforbindelser

Country Status (27)

Country Link
US (1) US5744483A (de)
EP (1) EP0741724B1 (de)
JP (1) JP2866743B2 (de)
CN (1) CN1048247C (de)
AT (1) ATE183184T1 (de)
AU (1) AU684568B2 (de)
BR (2) BR9408506A (de)
CA (1) CA2182101C (de)
CO (1) CO4230161A1 (de)
CZ (1) CZ286757B6 (de)
DE (1) DE69420053T2 (de)
DK (1) DK0741724T3 (de)
EG (1) EG20672A (de)
ES (1) ES2134361T3 (de)
FI (1) FI113769B (de)
GR (1) GR3031356T3 (de)
HU (1) HU221633B1 (de)
IL (1) IL112415A (de)
MY (1) MY111623A (de)
NO (1) NO309190B1 (de)
NZ (1) NZ275151A (de)
PE (1) PE43795A1 (de)
PL (1) PL179448B1 (de)
RU (1) RU2126404C1 (de)
TW (1) TW449591B (de)
WO (1) WO1995020587A1 (de)
ZA (1) ZA95692B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2232059A1 (en) * 1995-09-15 1997-03-20 Bertrand Leo Chenard Phenol derivatives with pharmaceutical activity
TW498067B (en) * 1996-07-19 2002-08-11 Hoffmann La Roche 4-hydroxy-piperidine derivatives
EP1674087A1 (de) 2000-10-02 2006-06-28 Pfizer Products Inc. Prophylaktische Verwendung von N-Methyl-D-Aspartat Rezeptor (NMDA) Antagonisten
ZA200108038B (en) * 2000-10-02 2003-04-01 Pfizer Prod Inc Prophylactic use of n-methyl-d-asparrate (NMDA) antagonists.
SE0100902D0 (sv) 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
WO2005051919A1 (en) * 2003-11-26 2005-06-09 Pfizer Products Inc. Aminopyrazole derivatives as gsk-3 inhibitors
ES2359735T3 (es) 2005-11-03 2011-05-26 F. Hoffmann-La Roche Ag Arilsulfonilcromanos como inhibidores de 5-ht6.
EP1976843B1 (de) * 2006-01-20 2013-09-04 Merck Sharp & Dohme Corp. Carbocyclische und heterocyclische arylsulfone als gamma-sekretase-hemmer
EP2522647B1 (de) * 2011-05-10 2014-04-30 DSM IP Assets B.V. Verfahren zum Trennen von chiralen Isomeren von Chromverbindungen und ihre Derivate und Vorläufer

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3294804A (en) * 1961-01-27 1966-12-27 Sterling Drug Inc 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-4-propionoxy-piperidine
FR5733M (de) * 1966-09-27 1968-01-22
GB1495526A (en) * 1974-05-31 1977-12-21 Beecham Group Ltd Chroman derivatives
US4016281A (en) * 1975-02-22 1977-04-05 Merck Patent Gesellschaft Mit Beschrankter Haftung Tetralone and indanone compounds
US4082755A (en) * 1977-02-14 1978-04-04 Janssen Pharmaceutica N.V. 1-[(Diarylmethyl)aminoalkyl]piperidimes
WO1980000152A1 (en) * 1978-07-03 1980-02-07 Sandoz Ag 3-aminopropoxy-aryl derivates,preparation and use thereof
US4358456A (en) * 1980-05-03 1982-11-09 John Wyeth & Brother Limited Antipsychotic piperidinomethyl-indole derivatives
DE3045688A1 (de) * 1980-12-04 1982-07-08 C.H. Boehringer Sohn, 6507 Ingelheim Neue 8-arylalkyl-3-phenyl-3-nortropanole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3274350D1 (en) * 1981-09-25 1987-01-08 Beecham Group Plc Pharmaceutically active benzopyran compounds
EP0093534A1 (de) * 1982-04-28 1983-11-09 Beecham Group Plc Chromanolen
GB8308064D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
FR2581993B1 (fr) * 1985-05-14 1988-03-18 Synthelabo Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
US4957928A (en) * 1986-06-26 1990-09-18 Ciba-Geigy Corporation Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
US4968678A (en) * 1988-02-19 1990-11-06 Eli Lilly And Company Tetrazole excitatory amino acid receptor antagonists
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
US4968878A (en) * 1989-02-07 1990-11-06 Transitions Research Corporation Dual bumper-light curtain obstacle detection sensor
US4902695A (en) * 1989-02-13 1990-02-20 Eli Lilly And Company Excitatory amino acid receptor antagonists
SK232890A3 (en) * 1989-05-17 1998-11-04 Pfizer 2-piperidino and 2-pyrrolidino-1-alkanols derivatives and preparation method thereof
MX24433A (es) * 1990-02-06 1993-05-01 Pfizer Derivados de 3-piperidino-1-cromanol y sus analogos y procedimiento para su preparacion
US5192751A (en) * 1992-07-24 1993-03-09 Eli Lilly And Company Use of competitive NMDA receptor antagonists in the treatment of urinary incontinence

Also Published As

Publication number Publication date
MY111623A (en) 2000-09-27
PL179448B1 (pl) 2000-09-29
HU221633B1 (hu) 2002-12-28
NZ275151A (en) 1998-02-26
JP2866743B2 (ja) 1999-03-08
ATE183184T1 (de) 1999-08-15
CZ286757B6 (en) 2000-06-14
WO1995020587A1 (en) 1995-08-03
FI950403A0 (fi) 1995-01-30
AU684568B2 (en) 1997-12-18
NO309190B1 (no) 2000-12-27
CN1142825A (zh) 1997-02-12
JPH09501698A (ja) 1997-02-18
AU8066394A (en) 1995-08-15
EG20672A (en) 1999-11-30
CO4230161A1 (es) 1995-10-19
EP0741724A1 (de) 1996-11-13
DE69420053T2 (de) 1999-11-25
PL315681A1 (en) 1996-11-25
RU2126404C1 (ru) 1999-02-20
CA2182101C (en) 1999-08-03
HUT75942A (en) 1997-05-28
BR9500380A (pt) 1995-10-17
FI113769B (fi) 2004-06-15
HU9602100D0 (en) 1996-09-30
PE43795A1 (es) 1995-12-09
ZA95692B (en) 1996-07-30
EP0741724B1 (de) 1999-08-11
TW449591B (en) 2001-08-11
BR9408506A (pt) 1997-08-05
IL112415A0 (en) 1995-03-30
FI950403A (fi) 1995-08-01
IL112415A (en) 1999-07-14
ES2134361T3 (es) 1999-10-01
NO963186L (no) 1996-07-30
NO963186D0 (no) 1996-07-30
CN1048247C (zh) 2000-01-12
GR3031356T3 (en) 2000-01-31
DE69420053D1 (de) 1999-09-16
CZ225696A3 (en) 1997-01-15
US5744483A (en) 1998-04-28
CA2182101A1 (en) 1995-08-03

Similar Documents

Publication Publication Date Title
DE69523169D1 (de) Verwendung von Mangiferin oder seinen Derivaten zur kosmetischen Anwendung
FI964332A (fi) Eräiden metaanibisfosfonihappojohdannaisten käyttö proteesin löystymisen ja proteesin vaelluksen estämiseen
DK0946162T3 (da) Anvendelse af p-aminophenol-derivater til fremstilling af farmaceutiske præparater, som er nyttige til behandlingen af neurodegenerative sygdomme
DK0741724T3 (da) Neurobeskyttende chromanforbindelser
DE69516110T2 (de) Verwendung von riluzol zur behandlung mitochondrialer erkrankungen
NO20012310D0 (no) Optisk aktiv pyridyl-4H-1,2,4-oksazdiazinderivat og dets anvendelse ved behandling av karsykdommer
EP0653936A1 (de) Verwendung von 2-[4-(-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphtoquinon zur behandlung von krebs.
NO20091111L (no) Anvendelse av R(+)-alfa-(2,3-dimetoksyfenyl)-l-[2-(4-fluorfenyl)etyl]-4-piperidin-metanol for behandling av sovnforstyrrelser
NZ268914A (en) Use of efaroxan and derivatives to prepare medicaments for treating neurodegenerative diseases especially alzheimer's disease