DK0726892T3 - (E)-20(22)-dehydrovitamin D-forbindelser - Google Patents

(E)-20(22)-dehydrovitamin D-forbindelser

Info

Publication number
DK0726892T3
DK0726892T3 DK94931429T DK94931429T DK0726892T3 DK 0726892 T3 DK0726892 T3 DK 0726892T3 DK 94931429 T DK94931429 T DK 94931429T DK 94931429 T DK94931429 T DK 94931429T DK 0726892 T3 DK0726892 T3 DK 0726892T3
Authority
DK
Denmark
Prior art keywords
compounds
dehydrovitamin
treatment
diseases
osteoporosis
Prior art date
Application number
DK94931429T
Other languages
English (en)
Inventor
Hector F Deluca
Rafal R Sicinski
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of DK0726892T3 publication Critical patent/DK0726892T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
DK94931429T 1993-11-03 1994-10-19 (E)-20(22)-dehydrovitamin D-forbindelser DK0726892T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/147,663 US5565589A (en) 1993-11-03 1993-11-03 17-formyl-5,6-trans-vitamin D compounds
PCT/US1994/012084 WO1995012575A1 (en) 1993-11-03 1994-10-19 (e)-20(22)-dehydrovitamin d compounds

Publications (1)

Publication Number Publication Date
DK0726892T3 true DK0726892T3 (da) 1999-08-30

Family

ID=22522410

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94931429T DK0726892T3 (da) 1993-11-03 1994-10-19 (E)-20(22)-dehydrovitamin D-forbindelser

Country Status (10)

Country Link
US (5) US5565589A (da)
EP (1) EP0726892B1 (da)
JP (1) JPH09504549A (da)
AT (1) ATE175194T1 (da)
AU (1) AU8051594A (da)
DE (1) DE69415690T2 (da)
DK (1) DK0726892T3 (da)
ES (1) ES2126157T3 (da)
GR (1) GR3029449T3 (da)
WO (1) WO1995012575A1 (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US20040167106A1 (en) * 1993-06-04 2004-08-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of a Vitamin D compound
US5869472A (en) * 1994-07-18 1999-02-09 Bone Care International, Inc. Synthesis of 1α-hydroxy vitamin D
US6929364B1 (en) * 1995-04-04 2005-08-16 Oakley, Inc. Contoured metal eyeglass frames
US5805261A (en) * 1995-04-04 1998-09-08 Oakley, Inc. Biased eyeglass frames
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US5843928A (en) * 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
GB9721156D0 (en) 1997-10-06 1997-12-03 Leo Pharm Prod Ltd Novel vitamin d analogues
AU1153201A (en) * 1999-10-25 2001-05-08 Strakan Limited Uses of 1,25-dihydroxy-5,6-trans vitamin D compounds and derivatives thereof
US7122533B2 (en) * 1999-11-29 2006-10-17 The United States Of America As Represented By The Department Of Health And Human Services Cosalane compounds and methods for their use
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
ATE399151T1 (de) * 2000-05-31 2008-07-15 Wisconsin Alumni Res Found 2-ethyl und 2-ethyliden-19-nor-vitamin d- verbindungen
US7491711B2 (en) * 2001-09-21 2009-02-17 Roche Palo Alto Llc Methods of treatment using 3-desoxy vitamin D3 analogs
US20030195175A1 (en) * 2002-03-25 2003-10-16 Deluca Hector F. Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone
CA2516233C (en) * 2003-04-10 2011-09-20 Wisconsin Alumni Research Foundation 2-propylidene-19-nor-vitamin d compounds
CA2586679A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
US7448750B2 (en) * 2006-09-22 2008-11-11 Oakley, Inc. Quadrilateral lens
WO2010003143A1 (en) 2008-07-03 2010-01-07 Oakley, Inc. Floating lens mounting system
US20120130133A1 (en) * 2008-11-26 2012-05-24 Cytochroma Inc. Method For Synthesizing Vitamin D Analogs
US8192015B2 (en) 2009-01-09 2012-06-05 Oakley, Inc. Eyeglass with enhanced ballistic resistance
US8469510B2 (en) 2009-01-09 2013-06-25 Oakley, Inc. Eyewear with enhanced ballistic resistance
CR20170434A (es) 2009-01-27 2017-11-21 Berg Llc VITAMINA D3 Y ANALOGOS DE LA MISMA PARA ALIVIAR EFECTOS SECUNDARIOS ASOCIADOS CON LA QUIMIOTERAPIA. (Divisional 2011-0445)
EP3603646B1 (en) 2009-08-14 2024-04-03 BPGbio, Inc. Vitamin d3 and analogs thereof for treating alopecia
EP2547299B1 (en) 2010-03-19 2017-08-16 Oakley, Inc. Eyewear
AU2011289179A1 (en) 2010-08-13 2013-03-14 Oakley, Inc. Eyewear with lens retention mechanism
WO2013044146A1 (en) 2011-09-22 2013-03-28 Oakley, Inc. Mounting mechanism for eyewear
US9122078B2 (en) 2011-12-01 2015-09-01 Oakley, Inc. Releasable earstem mounting mechanism for eyewear
EP2890341A2 (en) 2012-08-31 2015-07-08 Oakley, Inc. Eyewear having removably attached eyewear attachment
AU2013359369A1 (en) 2012-12-11 2015-06-18 Oakley, Inc. Eyewear with outriggers
WO2014138159A1 (en) 2013-03-07 2014-09-12 Oakley, Inc. Regeneratable ant-fogging element for goggle
KR20160013201A (ko) 2013-05-29 2016-02-03 버그 엘엘씨 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화
CN207867173U (zh) 2014-03-27 2018-09-14 奥克利有限公司 一种护目镜
JP6773288B2 (ja) 2015-10-09 2020-10-21 オークリー インコーポレイテッド 受動的通気及び取り外し可能なレンズを有する頭部装着支持体
US9709817B2 (en) 2015-12-07 2017-07-18 Oakley, Inc. Eyewear retention devices and methods
CN209433137U (zh) 2015-12-08 2019-09-24 奥克利有限公司 眼镜牵引装置
US10359642B2 (en) 2016-04-22 2019-07-23 Oakley, Inc. Mounting mechanism for eyewear
CN114685337B (zh) * 2022-04-24 2023-08-29 浙江花园生物高科股份有限公司 一种艾地骨化醇的制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR570829A (fr) * 1923-09-14 1924-05-07 Anciens Etablissements R Corne Dispositif de commande du mouvement d'écartement et de rapprochement des aiguilles dans les machines à coudre et à broder faisant les ourlets et points à jour
US4172076A (en) * 1977-04-04 1979-10-23 Diamond Shamrock Corporation Process for preparing steroidal acids and their intermediate derivatives
US4338250A (en) * 1981-04-27 1982-07-06 Wisconsin Alumni Research Foundation 1-Hydroxylation process
US4769181A (en) * 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
US4857518A (en) * 1984-10-04 1989-08-15 Wisconsin Alumni Research Foundation Hydroxylated 24-homo-vitamin D derivatives and methods for preparing same
EP0184112B1 (en) * 1984-11-27 1990-05-09 Chugai Seiyaku Kabushiki Kaisha Novel vitamin d derivatives and process for producing the same
WO1987000834A1 (en) * 1985-08-02 1987-02-12 Leo Pharmaceutical Products Ltd. A/S Novel vitamin d analogues
JPH0755960B2 (ja) * 1986-11-14 1995-06-14 日清製粉株式会社 ステロイド誘導体およびその製造方法
WO1989010351A1 (en) * 1988-04-21 1989-11-02 Leo Pharmaceutical Products Ltd. A/S (Løvens Kemis Novel vitamin d analogues
KR940003360B1 (ko) * 1988-04-29 1994-04-21 위스콘신 알럼나이 리써취 파운데이션 불포화 측쇄를 갖는 1α-히드록시비타민 D동족체
US5250523A (en) * 1988-04-29 1993-10-05 Wisconsin Alumni Research Foundation Side chain unsaturated 1α-hydroxyvitanim D homologs
JPH075542B2 (ja) * 1988-09-14 1995-01-25 呉羽化学工業株式会社 ビタミンｄ▲下３▼誘導体及びその製造方法
US4973584A (en) * 1989-03-09 1990-11-27 Deluca Hector F Novel 1α-hydroxyvitamin D2 epimer and derivatives
US5401731A (en) * 1989-06-29 1995-03-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) Vitamin D analogues
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5089641A (en) * 1991-03-11 1992-02-18 Wisconsin Alumni Research Foundation Synthesis of 1α-hydroxy-secosterol compounds
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
ES2093180T3 (es) * 1991-07-05 1996-12-16 Duphar Int Res Compuesto de vitamina d, metodo de preparar este compuesto y producto intermedio de dicho metodo.
US5182393A (en) * 1991-08-09 1993-01-26 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds

Also Published As

Publication number Publication date
US5488044A (en) 1996-01-30
US5484781A (en) 1996-01-16
ATE175194T1 (de) 1999-01-15
GR3029449T3 (en) 1999-05-28
ES2126157T3 (es) 1999-03-16
WO1995012575A1 (en) 1995-05-11
AU8051594A (en) 1995-05-23
US5536828A (en) 1996-07-16
DE69415690T2 (de) 1999-05-20
DE69415690D1 (de) 1999-02-11
EP0726892A1 (en) 1996-08-21
US5565589A (en) 1996-10-15
US5484782A (en) 1996-01-16
JPH09504549A (ja) 1997-05-06
EP0726892B1 (en) 1998-12-30

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