ATE175194T1 - (e)-20(22)-dehydrovitamin-d-verbindungen - Google Patents

(e)-20(22)-dehydrovitamin-d-verbindungen

Info

Publication number
ATE175194T1
ATE175194T1 AT94931429T AT94931429T ATE175194T1 AT E175194 T1 ATE175194 T1 AT E175194T1 AT 94931429 T AT94931429 T AT 94931429T AT 94931429 T AT94931429 T AT 94931429T AT E175194 T1 ATE175194 T1 AT E175194T1
Authority
AT
Austria
Prior art keywords
compounds
dehydrovitamin
treatment
diseases
osteoporosis
Prior art date
Application number
AT94931429T
Other languages
English (en)
Inventor
Hector F Deluca
Rafal R Sicinski
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of ATE175194T1 publication Critical patent/ATE175194T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0042Nitrogen only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94931429T 1993-11-03 1994-10-19 (e)-20(22)-dehydrovitamin-d-verbindungen ATE175194T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/147,663 US5565589A (en) 1993-11-03 1993-11-03 17-formyl-5,6-trans-vitamin D compounds

Publications (1)

Publication Number Publication Date
ATE175194T1 true ATE175194T1 (de) 1999-01-15

Family

ID=22522410

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94931429T ATE175194T1 (de) 1993-11-03 1994-10-19 (e)-20(22)-dehydrovitamin-d-verbindungen

Country Status (10)

Country Link
US (5) US5565589A (de)
EP (1) EP0726892B1 (de)
JP (1) JPH09504549A (de)
AT (1) ATE175194T1 (de)
AU (1) AU8051594A (de)
DE (1) DE69415690T2 (de)
DK (1) DK0726892T3 (de)
ES (1) ES2126157T3 (de)
GR (1) GR3029449T3 (de)
WO (1) WO1995012575A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040167106A1 (en) * 1993-06-04 2004-08-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of a Vitamin D compound
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US5869472A (en) * 1994-07-18 1999-02-09 Bone Care International, Inc. Synthesis of 1α-hydroxy vitamin D
US5805261A (en) * 1995-04-04 1998-09-08 Oakley, Inc. Biased eyeglass frames
US6929364B1 (en) * 1995-04-04 2005-08-16 Oakley, Inc. Contoured metal eyeglass frames
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
US6034074A (en) * 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US5843928A (en) * 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
GB9721156D0 (en) 1997-10-06 1997-12-03 Leo Pharm Prod Ltd Novel vitamin d analogues
WO2001030751A2 (en) * 1999-10-25 2001-05-03 Strakan Limited USES OF 1,25-DIHYDROXY-5,6-trans VITAMIN D COMPOUNDS AND DERIVATIVES THEREOF
US7122533B2 (en) * 1999-11-29 2006-10-17 The United States Of America As Represented By The Department Of Health And Human Services Cosalane compounds and methods for their use
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
ATE399151T1 (de) 2000-05-31 2008-07-15 Wisconsin Alumni Res Found 2-ethyl und 2-ethyliden-19-nor-vitamin d- verbindungen
US7491711B2 (en) * 2001-09-21 2009-02-17 Roche Palo Alto Llc Methods of treatment using 3-desoxy vitamin D3 analogs
US20030195175A1 (en) * 2002-03-25 2003-10-16 Deluca Hector F. Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone
MXPA05009336A (es) * 2003-04-10 2005-11-04 Wisconsin Alumni Res Found Compuestos de 2-propiliden-19-nor-vitamina d.
AU2005303773A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer
US7448750B2 (en) * 2006-09-22 2008-11-11 Oakley, Inc. Quadrilateral lens
JP5676439B2 (ja) 2008-07-03 2015-02-25 オークリー インコーポレイテッド 浮遊レンズ取り付けシステム
CN102264751A (zh) * 2008-11-26 2011-11-30 赛特克罗公司 合成维生素d类似物的方法
US8192015B2 (en) 2009-01-09 2012-06-05 Oakley, Inc. Eyeglass with enhanced ballistic resistance
US8469510B2 (en) 2009-01-09 2013-06-25 Oakley, Inc. Eyewear with enhanced ballistic resistance
JP5932339B2 (ja) 2009-01-27 2016-06-08 バーグ エルエルシー 化学療法に付随する副作用を軽減するためのビタミンd3およびその類似体
IN2012DN02137A (de) 2009-08-14 2015-08-07 Berg Biosystems Llc
CA2855170C (en) 2010-03-19 2016-11-01 Oakley, Inc. Eyewear
EP2603830A1 (de) 2010-08-13 2013-06-19 Oakley, Inc. Brille mit linsenfixiermechanismus
AU2012312125B2 (en) 2011-09-22 2015-07-09 Oakley, Inc. Mounting mechanism for eyewear
US9122078B2 (en) 2011-12-01 2015-09-01 Oakley, Inc. Releasable earstem mounting mechanism for eyewear
CN205007112U (zh) 2012-08-31 2016-02-03 奥克利有限公司 具有多个通风状态的眼睛佩戴物及眼睛佩戴物附件
GB2522389B (en) 2012-12-11 2019-07-31 Oakley Inc Eyewear with outriggers
WO2014138159A1 (en) 2013-03-07 2014-09-12 Oakley, Inc. Regeneratable ant-fogging element for goggle
SG10201709894RA (en) 2013-05-29 2018-01-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN207867173U (zh) 2014-03-27 2018-09-14 奥克利有限公司 一种护目镜
EP3360006A1 (de) 2015-10-09 2018-08-15 Oakley, Inc. Am kopf getragene gestelle mit passiver entlüftung und abnehmbarer linse
US9709817B2 (en) 2015-12-07 2017-07-18 Oakley, Inc. Eyewear retention devices and methods
CN209433137U (zh) 2015-12-08 2019-09-24 奥克利有限公司 眼镜牵引装置
US10359642B2 (en) 2016-04-22 2019-07-23 Oakley, Inc. Mounting mechanism for eyewear
CN114685337B (zh) * 2022-04-24 2023-08-29 浙江花园生物高科股份有限公司 一种艾地骨化醇的制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR570829A (fr) * 1923-09-14 1924-05-07 Anciens Etablissements R Corne Dispositif de commande du mouvement d'écartement et de rapprochement des aiguilles dans les machines à coudre et à broder faisant les ourlets et points à jour
US4172076A (en) * 1977-04-04 1979-10-23 Diamond Shamrock Corporation Process for preparing steroidal acids and their intermediate derivatives
US4338250A (en) * 1981-04-27 1982-07-06 Wisconsin Alumni Research Foundation 1-Hydroxylation process
US4769181A (en) * 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
US4857518A (en) * 1984-10-04 1989-08-15 Wisconsin Alumni Research Foundation Hydroxylated 24-homo-vitamin D derivatives and methods for preparing same
DE3577552D1 (de) * 1984-11-27 1990-06-13 Chugai Pharmaceutical Co Ltd Vitamin d-derivate und verfahren zu deren herstellung.
WO1987000834A1 (en) * 1985-08-02 1987-02-12 Leo Pharmaceutical Products Ltd. A/S Novel vitamin d analogues
JPH0755960B2 (ja) * 1986-11-14 1995-06-14 日清製粉株式会社 ステロイド誘導体およびその製造方法
KR0144358B1 (ko) * 1988-04-21 1998-07-15 피. 라이달 크리스텐슨 비타민 d 동족체
US5250523A (en) * 1988-04-29 1993-10-05 Wisconsin Alumni Research Foundation Side chain unsaturated 1α-hydroxyvitanim D homologs
EP0374219A1 (de) 1988-04-29 1990-06-27 Wisconsin Alumni Research Foundation In den seitenketten ungesättigte 1-alpha-hydroxy-vitamin-d-homologe
JPH075542B2 (ja) * 1988-09-14 1995-01-25 呉羽化学工業株式会社 ビタミンd▲下3▼誘導体及びその製造方法
US4973584A (en) * 1989-03-09 1990-11-27 Deluca Hector F Novel 1α-hydroxyvitamin D2 epimer and derivatives
US5401731A (en) * 1989-06-29 1995-03-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) Vitamin D analogues
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5089641A (en) * 1991-03-11 1992-02-18 Wisconsin Alumni Research Foundation Synthesis of 1α-hydroxy-secosterol compounds
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
ES2093180T3 (es) * 1991-07-05 1996-12-16 Duphar Int Res Compuesto de vitamina d, metodo de preparar este compuesto y producto intermedio de dicho metodo.
US5182393A (en) * 1991-08-09 1993-01-26 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds

Also Published As

Publication number Publication date
EP0726892B1 (de) 1998-12-30
US5536828A (en) 1996-07-16
DE69415690T2 (de) 1999-05-20
DK0726892T3 (da) 1999-08-30
US5484781A (en) 1996-01-16
EP0726892A1 (de) 1996-08-21
DE69415690D1 (de) 1999-02-11
GR3029449T3 (en) 1999-05-28
US5484782A (en) 1996-01-16
US5565589A (en) 1996-10-15
WO1995012575A1 (en) 1995-05-11
US5488044A (en) 1996-01-30
AU8051594A (en) 1995-05-23
ES2126157T3 (es) 1999-03-16
JPH09504549A (ja) 1997-05-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee