DK0724431T3 - Fremgangsmåder og sammensætninger til mikroindkapsling af adjuvanser - Google Patents

Fremgangsmåder og sammensætninger til mikroindkapsling af adjuvanser

Info

Publication number
DK0724431T3
DK0724431T3 DK94930768T DK94930768T DK0724431T3 DK 0724431 T3 DK0724431 T3 DK 0724431T3 DK 94930768 T DK94930768 T DK 94930768T DK 94930768 T DK94930768 T DK 94930768T DK 0724431 T3 DK0724431 T3 DK 0724431T3
Authority
DK
Denmark
Prior art keywords
adjuvants
compositions
methods
microencapsulating
adjuvant
Prior art date
Application number
DK94930768T
Other languages
English (en)
Inventor
Jeffrey L Cleland
Amy Lim
Michael Frank Powell
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK0724431T3 publication Critical patent/DK0724431T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK94930768T 1993-10-22 1994-10-13 Fremgangsmåder og sammensætninger til mikroindkapsling af adjuvanser DK0724431T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14134193A 1993-10-22 1993-10-22
US14333293A 1993-10-25 1993-10-25
PCT/US1994/011674 WO1995011008A2 (en) 1993-10-22 1994-10-13 Methods and compositions for microencapsulation of adjuvants

Publications (1)

Publication Number Publication Date
DK0724431T3 true DK0724431T3 (da) 2003-01-06

Family

ID=26839008

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94930768T DK0724431T3 (da) 1993-10-22 1994-10-13 Fremgangsmåder og sammensætninger til mikroindkapsling af adjuvanser

Country Status (9)

Country Link
EP (1) EP0724431B1 (da)
JP (1) JPH09504523A (da)
AT (1) ATE223702T1 (da)
AU (1) AU7979094A (da)
CA (1) CA2172507C (da)
DE (1) DE69431358T2 (da)
DK (1) DK0724431T3 (da)
ES (1) ES2182850T3 (da)
WO (1) WO1995011008A2 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69426292T2 (de) * 1993-02-23 2001-05-17 Genentech, Inc. Stabilisierung von mit organischen lösungsmittel behandelten polypeptiden mit einem hilfsstoff
WO1995011009A1 (en) * 1993-10-22 1995-04-27 Genentech, Inc. Method for preparing microspheres comprising a fluidized bed drying step
AU684324B2 (en) * 1993-11-19 1997-12-11 Alkermes Controlled Therapeutics Inc. Ii Preparation of biodegradable microparticles containing a biologically active agent
GB9709900D0 (en) * 1997-05-15 1997-07-09 Microbiological Res Authority Microencapsulated DNA for vaccination and gene therapy
AU722884B2 (en) * 1996-01-24 2000-08-10 United States Government Represented By The Secretary Of The Army Novel "burst-free" sustained release poly-(lactide/glycolide) microspheres
WO1998034594A1 (en) * 1997-02-06 1998-08-13 Merck & Co., Inc. Thimerosal-free preservatives for vaccines
EP1579851A3 (en) * 1997-08-29 2009-09-02 Corixa Corporation Rapid release encapsulated bioactive agents for inducing or potentiating an immune response and methods of use thereof
US6750324B1 (en) 1997-12-02 2004-06-15 Neuralab Limited Humanized and chimeric N-terminal amyloid beta-antibodies
US6905686B1 (en) 1997-12-02 2005-06-14 Neuralab Limited Active immunization for treatment of alzheimer's disease
US7964192B1 (en) 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
US6761888B1 (en) 2000-05-26 2004-07-13 Neuralab Limited Passive immunization treatment of Alzheimer's disease
US6787523B1 (en) 1997-12-02 2004-09-07 Neuralab Limited Prevention and treatment of amyloidogenic disease
US20030147882A1 (en) 1998-05-21 2003-08-07 Alan Solomon Methods for amyloid removal using anti-amyloid antibodies
US7087236B1 (en) 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
CA2341352C (en) 1998-09-01 2013-01-08 Elan Corporation Plc Oral vaccine compositions
US6787637B1 (en) 1999-05-28 2004-09-07 Neuralab Limited N-Terminal amyloid-β antibodies
JP2003522151A (ja) * 2000-02-08 2003-07-22 インスティテュート・オブ・モレキュラー・アグロバイオロジー 腸炎菌を包含するバイオ分解性およびバイオ和合性の重合性ミクロスフェア
ES2160089B1 (es) * 2000-03-15 2002-05-16 Inst Cientifico Tecnol Navarra Procedimiento y aparato para la produccion de microparticulas para la liberacion controlada de farmacos hidrosolubles y vectores virales. aplicacion a la adiministracion de adn plasmidico y de adenovirus recombinantes defectivos.
US7700751B2 (en) 2000-12-06 2010-04-20 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize β-amyloid peptide
JP4137640B2 (ja) * 2001-03-09 2008-08-20 アイディー バイオメディカル コーポレイション オブ ケベック 新規プロテオソーム−リポサッカリドワクチンアジュバント
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
PE20050627A1 (es) 2003-05-30 2005-08-10 Wyeth Corp Anticuerpos humanizados que reconocen el peptido beta amiloideo
JP2008523815A (ja) 2004-12-15 2008-07-10 エラン ファーマ インターナショナル リミテッド 認知の改善における使用のためのヒト化アミロイドβ抗体
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
US20090004213A1 (en) 2007-03-26 2009-01-01 Immatics Biotechnologies Gmbh Combination therapy using active immunotherapy
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
UA99830C2 (uk) * 2007-06-06 2012-10-10 Дебио Ресшерчи Фармасютикю С.А. Фармацевтична композиція з пролонгованим вивільненням, виготовлена з мікрочастинок
EP2182983B1 (en) 2007-07-27 2014-05-21 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases with humanised anti-abeta antibodies
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
US8815253B2 (en) 2007-12-07 2014-08-26 Novartis Ag Compositions for inducing immune responses
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
EP2308478A1 (en) * 2009-10-06 2011-04-13 Abbott GmbH & Co. KG Delivery system for sustained release of a calcium-channel blocking agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
HU212924B (en) * 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion

Also Published As

Publication number Publication date
EP0724431B1 (en) 2002-09-11
EP0724431A1 (en) 1996-08-07
ATE223702T1 (de) 2002-09-15
ES2182850T3 (es) 2003-03-16
CA2172507C (en) 2008-12-02
AU7979094A (en) 1995-05-08
DE69431358T2 (de) 2003-06-05
DE69431358D1 (de) 2002-10-17
WO1995011008A3 (en) 1996-09-19
JPH09504523A (ja) 1997-05-06
WO1995011008A2 (en) 1995-04-27
CA2172507A1 (en) 1995-04-27

Similar Documents

Publication Publication Date Title
DK0724431T3 (da) Fremgangsmåder og sammensætninger til mikroindkapsling af adjuvanser
DK0724432T3 (da) Fremgangsmåder og præparater til mikroindkapsling af antigener til brug som vacciner
DK1459766T3 (da) Adjuvanssammensætninger til forstærkning af immunresponser på polynukleotidbaserede vacciner
SE8000208L (sv) Externt benfixationselement
DK152068C (da) Forankringsindretning til stolper for hegn, autovaern, telte og lignende
KR950702125A (ko) 보조약을 함유하는 백신 조성물(vaccine composition containing adjuvants)
MX9306986A (es) Composiciones farmaceuticas a base de taxoides.
NO910812L (no) Peptidsyntesefremgangsmaate og fast baerer for anvendelse ifremgangsmaaten.
EA199900069A1 (ru) Вакцинная композиция против малярии
DK251589D0 (da) Fremgangsmaade til fremstilling af 1,3-dioler
MX9206687A (es) Metodos para preparar formas sinterizadas y composiciones utilizadas en los mismos.
DK4189D0 (da) Oxadiazolforbindelse, farmaceutisk praeparat indeholdende og fremgangsmaade til fremstilling af forbindelsen
ATE418070T1 (de) Dekodierung von matrixsensoren mit mikrokugeln
DE69227976D1 (de) Amphotere Zusammensetzungen
DK16187D0 (da) Farmaceutisk sammensaetning med langvarig frigoerelse og fremgangsmaade til fremstilling af samme
NO922385L (no) Mykt toerrfor, saerlig til bruk som avvenningsfor, og fremgangsmaate til fremstilling derav
ATE227122T1 (de) Stabilisierte tablettenformulierung
NO913482D0 (no) Anordning for fastholding av to eller flere seismiske energikilder i en fast innbyrdes avstand.
DK474889D0 (da) To-kammerpose til anvendelse som kunstig lunge
PL358081A1 (en) Inclusion bodies as antigenes in oral immunization of animals
ES2136965T3 (es) Derivados de 17-hidroxiiminoalquil y 17-hidroxiiminometilalquenil ciclopentanperhidrofenantreno activos sobre el sistema cardiovascular un procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
DK95691D0 (da) Kompositprotese og fremgangsmaade til fremstilling af samme
NO914440L (no) Fremgangsmaate for fremstilling av hoeystyrke-roereelementermed isotrope mekaniske egenskaper
DE50211461D1 (de) Pharmazeutische zusammensetzung enthaltend bulbophyllum
JPS52146891A (en) Fixture for attaching appliance