DK0716705T3 - Fremgangsmåde til rekombinant fremstilling af proteiner i gæren Hansenula - Google Patents
Fremgangsmåde til rekombinant fremstilling af proteiner i gæren HansenulaInfo
- Publication number
- DK0716705T3 DK0716705T3 DK94927528T DK94927528T DK0716705T3 DK 0716705 T3 DK0716705 T3 DK 0716705T3 DK 94927528 T DK94927528 T DK 94927528T DK 94927528 T DK94927528 T DK 94927528T DK 0716705 T3 DK0716705 T3 DK 0716705T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- proteins
- recombinant production
- hansenula
- date mar
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4329969A DE4329969A1 (de) | 1993-09-04 | 1993-09-04 | Verfahren zur rekombinanten Herstellung von Proteinen in Hefe |
| PCT/EP1994/002897 WO1995007356A1 (de) | 1993-09-04 | 1994-09-01 | Verfahren zur rekombinanten herstellung von proteinen in der hefe hansenula |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0716705T3 true DK0716705T3 (da) | 2000-07-10 |
Family
ID=6496878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94927528T DK0716705T3 (da) | 1993-09-04 | 1994-09-01 | Fremgangsmåde til rekombinant fremstilling af proteiner i gæren Hansenula |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5741674A (da) |
| EP (1) | EP0716705B1 (da) |
| JP (1) | JPH09502347A (da) |
| AT (1) | ATE191007T1 (da) |
| CA (1) | CA2169567A1 (da) |
| DE (2) | DE4329969A1 (da) |
| DK (1) | DK0716705T3 (da) |
| ES (1) | ES2145838T3 (da) |
| GR (1) | GR3033114T3 (da) |
| PT (1) | PT716705E (da) |
| WO (1) | WO1995007356A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19620443C2 (de) * | 1996-05-21 | 1998-09-17 | Rhein Biotech Proz & Prod Gmbh | Verfahren zum automatischen Durchführen von Bluttests |
| CA2954889A1 (en) | 2001-03-09 | 2002-09-19 | University Of Kentucky Research Foundation | Cytochrome p450s and uses thereof |
| CN103060216B (zh) * | 2008-05-06 | 2016-07-06 | 阿彻丹尼尔斯米德兰德公司 | 通过淀粉和木聚糖的降解酶的表达开发能进行淀粉和木聚糖的醇发酵的耐热酵母多形汉逊酵母菌株 |
| US9452212B2 (en) | 2011-04-14 | 2016-09-27 | Dynavax Technologies Corporation | Methods and compositions for eliciting an immune response against hepatitis B virus |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0173378B1 (en) * | 1984-07-27 | 1991-06-12 | Unilever N.V. | Process for preparing a polypeptide by culturing a transformed microorganism, a transformed microorganism suitable therefor and dna sequences suitable for preparing such microorganism |
| WO1992013951A1 (en) * | 1991-02-04 | 1992-08-20 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Production of human serum albumin in methylotrophic yeast cells |
-
1993
- 1993-09-04 DE DE4329969A patent/DE4329969A1/de not_active Withdrawn
-
1994
- 1994-09-01 AT AT94927528T patent/ATE191007T1/de active
- 1994-09-01 DK DK94927528T patent/DK0716705T3/da active
- 1994-09-01 ES ES94927528T patent/ES2145838T3/es not_active Expired - Lifetime
- 1994-09-01 CA CA002169567A patent/CA2169567A1/en not_active Abandoned
- 1994-09-01 US US08/605,053 patent/US5741674A/en not_active Expired - Lifetime
- 1994-09-01 JP JP7508437A patent/JPH09502347A/ja not_active Ceased
- 1994-09-01 PT PT94927528T patent/PT716705E/pt unknown
- 1994-09-01 DE DE59409242T patent/DE59409242D1/de not_active Expired - Lifetime
- 1994-09-01 WO PCT/EP1994/002897 patent/WO1995007356A1/de active IP Right Grant
- 1994-09-01 EP EP94927528A patent/EP0716705B1/de not_active Expired - Lifetime
-
2000
- 2000-03-30 GR GR20000400803T patent/GR3033114T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE4329969A1 (de) | 1995-03-09 |
| DE59409242D1 (de) | 2000-04-27 |
| EP0716705A1 (de) | 1996-06-19 |
| JPH09502347A (ja) | 1997-03-11 |
| ATE191007T1 (de) | 2000-04-15 |
| WO1995007356A1 (de) | 1995-03-16 |
| GR3033114T3 (en) | 2000-08-31 |
| US5741674A (en) | 1998-04-21 |
| CA2169567A1 (en) | 1995-03-16 |
| ES2145838T3 (es) | 2000-07-16 |
| PT716705E (pt) | 2000-09-29 |
| EP0716705B1 (de) | 2000-03-22 |
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