DK0709371T3 - O-arylmethyl-N-(thio)acyl-hydroxylaminer som ligander for melatoninreceptorer, fremgangsmåder til deres fremstilling og far - Google Patents
O-arylmethyl-N-(thio)acyl-hydroxylaminer som ligander for melatoninreceptorer, fremgangsmåder til deres fremstilling og farInfo
- Publication number
- DK0709371T3 DK0709371T3 DK95402375T DK95402375T DK0709371T3 DK 0709371 T3 DK0709371 T3 DK 0709371T3 DK 95402375 T DK95402375 T DK 95402375T DK 95402375 T DK95402375 T DK 95402375T DK 0709371 T3 DK0709371 T3 DK 0709371T3
- Authority
- DK
- Denmark
- Prior art keywords
- substd
- opt
- alkyl
- acyl
- cycloalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/08—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9412784A FR2726268B1 (fr) | 1994-10-26 | 1994-10-26 | Nouvelles o-arylmethyl n-(thio)acyl hydroxylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0709371T3 true DK0709371T3 (da) | 1999-02-15 |
Family
ID=9468216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95402375T DK0709371T3 (da) | 1994-10-26 | 1995-10-25 | O-arylmethyl-N-(thio)acyl-hydroxylaminer som ligander for melatoninreceptorer, fremgangsmåder til deres fremstilling og far |
Country Status (15)
Country | Link |
---|---|
US (1) | US5612368A (da) |
EP (1) | EP0709371B1 (da) |
JP (1) | JP2839468B2 (da) |
CN (1) | CN1048720C (da) |
AT (1) | ATE165816T1 (da) |
AU (1) | AU688965B2 (da) |
CA (1) | CA2161284C (da) |
DE (1) | DE69502371T2 (da) |
DK (1) | DK0709371T3 (da) |
ES (1) | ES2119337T3 (da) |
FI (1) | FI955084A (da) |
FR (1) | FR2726268B1 (da) |
NO (1) | NO305021B1 (da) |
NZ (1) | NZ280329A (da) |
ZA (1) | ZA959077B (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001288138A (ja) * | 2000-04-04 | 2001-10-16 | Kanto Denka Kogyo Co Ltd | 含フッ素α,β−不飽和カルボン酸の製造方法 |
UA95788C2 (en) | 2005-12-15 | 2011-09-12 | Ф. Хоффманн-Ля Рош Аг | Fused pyrrole derivatives |
FR2919606B1 (fr) * | 2007-08-03 | 2010-09-17 | Servier Lab | Nouveau procede de synthese du (7-methoxy-1-naphtyl) acetonitrile et application a la synthese de l'agomelatine. |
CA2890906A1 (en) * | 2012-11-16 | 2014-05-22 | The Regents Of The University Of California | Pictet-spengler ligation for protein chemical modification |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4923896A (en) * | 1989-02-09 | 1990-05-08 | Warner-Lambert Company | N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents |
FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2680366B1 (fr) * | 1991-08-13 | 1995-01-20 | Adir | Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2696453B1 (fr) * | 1992-10-02 | 1994-12-23 | Adir | Nouveaux arylalkyl(thio)amides, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent. |
-
1994
- 1994-10-26 FR FR9412784A patent/FR2726268B1/fr not_active Expired - Fee Related
-
1995
- 1995-10-19 NO NO954170A patent/NO305021B1/no not_active IP Right Cessation
- 1995-10-24 CA CA002161284A patent/CA2161284C/fr not_active Expired - Fee Related
- 1995-10-25 CN CN95117658A patent/CN1048720C/zh not_active Expired - Fee Related
- 1995-10-25 DK DK95402375T patent/DK0709371T3/da active
- 1995-10-25 FI FI955084A patent/FI955084A/fi unknown
- 1995-10-25 ES ES95402375T patent/ES2119337T3/es not_active Expired - Lifetime
- 1995-10-25 DE DE69502371T patent/DE69502371T2/de not_active Expired - Fee Related
- 1995-10-25 NZ NZ280329A patent/NZ280329A/en unknown
- 1995-10-25 US US08/548,209 patent/US5612368A/en not_active Expired - Fee Related
- 1995-10-25 AU AU34451/95A patent/AU688965B2/en not_active Ceased
- 1995-10-25 AT AT95402375T patent/ATE165816T1/de not_active IP Right Cessation
- 1995-10-25 EP EP95402375A patent/EP0709371B1/fr not_active Expired - Lifetime
- 1995-10-26 ZA ZA959077A patent/ZA959077B/xx unknown
- 1995-10-26 JP JP7278761A patent/JP2839468B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO954170L (no) | 1996-04-29 |
JP2839468B2 (ja) | 1998-12-16 |
JPH08225520A (ja) | 1996-09-03 |
NO305021B1 (no) | 1999-03-22 |
CA2161284A1 (fr) | 1996-04-27 |
NO954170D0 (no) | 1995-10-19 |
CN1048720C (zh) | 2000-01-26 |
ES2119337T3 (es) | 1998-10-01 |
NZ280329A (en) | 1996-11-26 |
AU3445195A (en) | 1996-05-09 |
ZA959077B (en) | 1996-05-22 |
US5612368A (en) | 1997-03-18 |
AU688965B2 (en) | 1998-03-19 |
FI955084A0 (fi) | 1995-10-25 |
CN1127247A (zh) | 1996-07-24 |
ATE165816T1 (de) | 1998-05-15 |
EP0709371A1 (fr) | 1996-05-01 |
DE69502371D1 (de) | 1998-06-10 |
EP0709371B1 (fr) | 1998-05-06 |
FR2726268B1 (fr) | 1996-12-06 |
DE69502371T2 (de) | 1998-12-17 |
FR2726268A1 (fr) | 1996-05-03 |
FI955084A (fi) | 1996-04-27 |
CA2161284C (fr) | 1999-05-18 |
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