DK0699305T3 - Fremgangsmåder, agenser og kit til påvisning af organophosphorforbindelser - Google Patents
Fremgangsmåder, agenser og kit til påvisning af organophosphorforbindelserInfo
- Publication number
- DK0699305T3 DK0699305T3 DK94915246T DK94915246T DK0699305T3 DK 0699305 T3 DK0699305 T3 DK 0699305T3 DK 94915246 T DK94915246 T DK 94915246T DK 94915246 T DK94915246 T DK 94915246T DK 0699305 T3 DK0699305 T3 DK 0699305T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibodies
- protein
- methods
- methyl
- raising
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000002903 organophosphorus compounds Chemical class 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 239000000575 pesticide Substances 0.000 abstract 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 abstract 1
- FGIWFCGDPUIBEZ-UHFFFAOYSA-N Etrimfos Chemical compound CCOC1=CC(OP(=S)(OC)OC)=NC(CC)=N1 FGIWFCGDPUIBEZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005949 Malathion Substances 0.000 abstract 1
- NTAHCMPOMKHKEU-AATRIKPKSA-N Methacrifos Chemical compound COC(=O)C(\C)=C\OP(=S)(OC)OC NTAHCMPOMKHKEU-AATRIKPKSA-N 0.000 abstract 1
- 108010058846 Ovalbumin Proteins 0.000 abstract 1
- 241000237988 Patellidae Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 229940098773 bovine serum albumin Drugs 0.000 abstract 1
- 210000000991 chicken egg Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- OEBRKCOSUFCWJD-UHFFFAOYSA-N dichlorvos Chemical compound COP(=O)(OC)OC=C(Cl)Cl OEBRKCOSUFCWJD-UHFFFAOYSA-N 0.000 abstract 1
- JXSJBGJIGXNWCI-UHFFFAOYSA-N diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate Chemical compound CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC JXSJBGJIGXNWCI-UHFFFAOYSA-N 0.000 abstract 1
- ZNOLGFHPUIJIMJ-UHFFFAOYSA-N fenitrothion Chemical compound COP(=S)(OC)OC1=CC=C([N+]([O-])=O)C(C)=C1 ZNOLGFHPUIJIMJ-UHFFFAOYSA-N 0.000 abstract 1
- 229960000453 malathion Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940092253 ovalbumin Drugs 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Luminescent Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939310238A GB9310238D0 (en) | 1993-05-18 | 1993-05-18 | Method,agents and kits for detection of organic agents |
| PCT/GB1994/001060 WO1994027149A1 (en) | 1993-05-18 | 1994-05-18 | Methods, agents and kits for detection of organophosphorus compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0699305T3 true DK0699305T3 (da) | 1998-11-23 |
Family
ID=10735700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94915246T DK0699305T3 (da) | 1993-05-18 | 1994-05-18 | Fremgangsmåder, agenser og kit til påvisning af organophosphorforbindelser |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US5830770A (de) |
| EP (1) | EP0699305B1 (de) |
| JP (1) | JPH08510231A (de) |
| AT (1) | ATE165165T1 (de) |
| AU (1) | AU6656694A (de) |
| DE (1) | DE69409643T2 (de) |
| DK (1) | DK0699305T3 (de) |
| ES (1) | ES2114686T3 (de) |
| GB (2) | GB9310238D0 (de) |
| GR (1) | GR3026668T3 (de) |
| WO (1) | WO1994027149A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9310238D0 (en) * | 1993-05-18 | 1993-07-14 | Mini Agriculture & Fisheries | Method,agents and kits for detection of organic agents |
| GB9515850D0 (en) * | 1995-08-02 | 1995-10-04 | Mini Agriculture & Fisheries | Broad specificity antibodies |
| US6635434B1 (en) | 1999-09-17 | 2003-10-21 | Exiqon A/S | Immunoassay for pesticides and their degradation products |
| JP2001275682A (ja) * | 2000-03-31 | 2001-10-09 | Kankyo Meneki Gijutsu Kenkyusho:Kk | 抗マラチオンモノクローナル抗体をコードする遺伝子 |
| US20020193685A1 (en) * | 2001-06-08 | 2002-12-19 | Calypso Medical, Inc. | Guided Radiation Therapy System |
| KR100423526B1 (ko) * | 2001-12-28 | 2004-03-18 | 이용태 | 유기인계 포스포로티오에이트 류 농약의 면역분석적검출에 이용되는 합텐의 제조방법 |
| KR100644205B1 (ko) | 2005-06-30 | 2006-11-10 | 이용태 | 유기인계 농약의 총체적 검출을 위한 합텐과 항체 및 이를이용한 면역분석방법 |
| CA2669571A1 (en) * | 2006-11-13 | 2008-07-03 | Ateris Technologies, Llc | Pesticide biomarker |
| CN101939339A (zh) * | 2007-11-14 | 2011-01-05 | 阿特瑞斯技术有限公司 | 生物标记的检测 |
| CN104262486B (zh) * | 2014-09-24 | 2017-03-15 | 江苏省农业科学院 | 杂交瘤细胞株fq‑2g3，其产生的抗甲基毒死蜱单克隆抗体及免疫层析试纸条 |
| CN107064494B (zh) * | 2017-04-17 | 2019-12-24 | 四川精卫食品检测科技有限公司 | 一种毒死蜱检测酶联免疫试剂盒 |
| CN110684110A (zh) * | 2019-09-20 | 2020-01-14 | 北京勤邦生物技术有限公司 | 一种甲基嘧啶磷单克隆抗体的制备及其应用 |
| CN110981907A (zh) * | 2019-11-05 | 2020-04-10 | 华南农业大学 | 一种马拉硫磷半抗原、人工抗原及其制备方法 |
| CN113388037B (zh) * | 2021-04-14 | 2022-04-29 | 华南农业大学 | 一种特异性识别杀螟硫磷纳米抗体的制备及其应用 |
| CN114720525B (zh) * | 2022-03-22 | 2024-01-05 | 华南农业大学 | 一种对硫磷免疫传感器及其制备方法与应用 |
| WO2023250034A1 (en) * | 2022-06-21 | 2023-12-28 | Thompson Charles M | Antibody-assisted detoxication of reactive organophosphorus compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5413915A (en) * | 1988-07-12 | 1995-05-09 | Resource Technologies Group, Inc. | Method and sensor for detecting toxic chemical exposure effects and metabolic activation of carcinogenic chemical agents |
| JPH088874B2 (ja) * | 1989-06-30 | 1996-01-31 | コモンウエルス・サイエンテイフイツク・アンド・インダストリアル・リサーチ・オーガナイゼイシヨン | フェニトロチオン及び近縁の有機リン酸エステルを測定するためのモノクローナル抗体及びポリクローナル抗体並びに検査方法 |
| DK0535060T3 (da) * | 1990-06-15 | 1995-07-17 | Hoechst Schering Agrevo Gmbh | Antifungisk polypeptid samt fremgangsmåde til dets fremstilling |
| US5283180A (en) * | 1990-07-19 | 1994-02-01 | Charm Sciences, Inc. | Bioluminescence method for the determination of pesticides |
| GB9310238D0 (en) * | 1993-05-18 | 1993-07-14 | Mini Agriculture & Fisheries | Method,agents and kits for detection of organic agents |
-
1993
- 1993-05-18 GB GB939310238A patent/GB9310238D0/en active Pending
-
1994
- 1994-05-18 EP EP94915246A patent/EP0699305B1/de not_active Expired - Lifetime
- 1994-05-18 DE DE69409643T patent/DE69409643T2/de not_active Expired - Fee Related
- 1994-05-18 GB GB9522508A patent/GB2293384B/en not_active Revoked
- 1994-05-18 AU AU66566/94A patent/AU6656694A/en not_active Abandoned
- 1994-05-18 WO PCT/GB1994/001060 patent/WO1994027149A1/en active IP Right Grant
- 1994-05-18 US US08/557,003 patent/US5830770A/en not_active Expired - Fee Related
- 1994-05-18 DK DK94915246T patent/DK0699305T3/da active
- 1994-05-18 AT AT94915246T patent/ATE165165T1/de not_active IP Right Cessation
- 1994-05-18 ES ES94915246T patent/ES2114686T3/es not_active Expired - Lifetime
- 1994-05-18 JP JP6525185A patent/JPH08510231A/ja active Pending
-
1998
- 1998-04-16 GR GR980400626T patent/GR3026668T3/el unknown
- 1998-05-01 US US09/070,748 patent/US6133049A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB9310238D0 (en) | 1993-07-14 |
| AU6656694A (en) | 1994-12-12 |
| US5830770A (en) | 1998-11-03 |
| EP0699305B1 (de) | 1998-04-15 |
| US6133049A (en) | 2000-10-17 |
| ATE165165T1 (de) | 1998-05-15 |
| GR3026668T3 (en) | 1998-07-31 |
| GB2293384B (en) | 1997-05-14 |
| ES2114686T3 (es) | 1998-06-01 |
| EP0699305A1 (de) | 1996-03-06 |
| DE69409643T2 (de) | 1998-08-06 |
| JPH08510231A (ja) | 1996-10-29 |
| DE69409643D1 (de) | 1998-05-20 |
| GB2293384A (en) | 1996-03-27 |
| GB9522508D0 (en) | 1996-01-03 |
| WO1994027149A1 (en) | 1994-11-24 |
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