DK0698025T3 - Ampa-antagonister samt fremgangsmåde til behandling dermed - Google Patents
Ampa-antagonister samt fremgangsmåde til behandling dermedInfo
- Publication number
- DK0698025T3 DK0698025T3 DK94917602T DK94917602T DK0698025T3 DK 0698025 T3 DK0698025 T3 DK 0698025T3 DK 94917602 T DK94917602 T DK 94917602T DK 94917602 T DK94917602 T DK 94917602T DK 0698025 T3 DK0698025 T3 DK 0698025T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- hydrogen
- treatment
- benzyl
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK55893A DK55893D0 (da) | 1993-05-13 | 1993-05-13 | Nye receptoraktive forbindelser, deres fremstilling og anvendelse |
DK13894 | 1994-02-02 | ||
PCT/EP1994/001492 WO1994026747A1 (en) | 1993-05-13 | 1994-05-09 | Ampa antagonists and a method of treatment therewith |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0698025T3 true DK0698025T3 (da) | 1998-08-24 |
Family
ID=26063386
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94917602T DK0698025T3 (da) | 1993-05-13 | 1994-05-09 | Ampa-antagonister samt fremgangsmåde til behandling dermed |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0698025B1 (sv) |
JP (1) | JP3439215B2 (sv) |
AT (1) | ATE161259T1 (sv) |
AU (1) | AU679075B2 (sv) |
CA (1) | CA2161783C (sv) |
DE (1) | DE69407407T2 (sv) |
DK (1) | DK0698025T3 (sv) |
ES (1) | ES2111930T3 (sv) |
FI (1) | FI954965A (sv) |
GR (1) | GR3026008T3 (sv) |
NO (1) | NO305287B1 (sv) |
NZ (1) | NZ267081A (sv) |
WO (1) | WO1994026747A1 (sv) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5597922A (en) * | 1994-07-29 | 1997-01-28 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Glycine receptor antagonist pharmacophore |
AU4423496A (en) * | 1995-03-14 | 1996-10-02 | Warner-Lambert Company | Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones |
US6110911A (en) * | 1995-06-07 | 2000-08-29 | Warner-Lambert Company | Cyclic amine derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists |
US5566694A (en) * | 1995-06-07 | 1996-10-22 | Allegheny Plastics, Inc. | Continuous pickling tank with expandable seals |
US5614508A (en) * | 1995-06-07 | 1997-03-25 | Warner-Lambert Company | Amino acid derivatives of substituted quinoxaline 2,3-dione derivatives as glutamate receptor antagonists |
US5874426A (en) * | 1995-06-07 | 1999-02-23 | Warner-Lambert Company | Cyclic amine derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists |
US5654303A (en) * | 1995-06-07 | 1997-08-05 | Warner-Lambert Company | Alkyl amine derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists |
US5773434A (en) * | 1995-08-30 | 1998-06-30 | Gary A. Rogers | Facilitation of AMPA receptor-mediated synaptic transmission in brain as a treatment for schizophrenia |
UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
US6063774A (en) * | 1996-12-16 | 2000-05-16 | Warner-Lambert Company | Tricyclic quinoxaline derivatives as neuroprotective agents |
US6172065B1 (en) | 1997-03-04 | 2001-01-09 | Warner-Lambert Company | Urea and thiourea derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists |
DE69922936T2 (de) | 1998-03-31 | 2005-12-08 | Neurosearch A/S | Verwendung von indol-2,3-dione-3-oximderivate als ampa-antagonisten |
US6096744A (en) * | 1998-05-04 | 2000-08-01 | Warner-Lambert Company | Sulfonamide derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists |
DE60041399D1 (de) | 1999-05-19 | 2009-03-05 | Painceptor Pharma Corp | Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen |
AU781067B2 (en) * | 2000-01-24 | 2005-05-05 | Neurosearch A/S | Isatine derivatives with neurotrophic activity |
DE10121215A1 (de) * | 2001-04-30 | 2002-10-31 | Merck Patent Gmbh | Dihydro-imidazo[4,5-e]indol- und 7H-Pyrrolo[3,2-f]chinoxalin Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden |
CN101346375B (zh) | 2005-11-23 | 2013-04-10 | 阿罗斯药物有限责任公司 | 调节门离子通道用组合物和方法 |
WO2007115409A1 (en) * | 2006-04-10 | 2007-10-18 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK146787A (da) * | 1987-03-23 | 1988-09-24 | Ferrosan | Heterocykliske forbindelser, deres fremstilling og anvendelse |
MX9204914A (es) * | 1991-08-28 | 1993-07-01 | Frank Watjen | Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende. |
EP0664807B1 (en) * | 1992-10-13 | 1997-09-10 | Warner-Lambert Company | Quinoxalinedione derivatives as eaa antagonists |
-
1994
- 1994-05-09 JP JP52494494A patent/JP3439215B2/ja not_active Expired - Fee Related
- 1994-05-09 ES ES94917602T patent/ES2111930T3/es not_active Expired - Lifetime
- 1994-05-09 AT AT94917602T patent/ATE161259T1/de not_active IP Right Cessation
- 1994-05-09 CA CA002161783A patent/CA2161783C/en not_active Expired - Fee Related
- 1994-05-09 NZ NZ267081A patent/NZ267081A/en not_active IP Right Cessation
- 1994-05-09 DE DE69407407T patent/DE69407407T2/de not_active Expired - Lifetime
- 1994-05-09 EP EP94917602A patent/EP0698025B1/en not_active Expired - Lifetime
- 1994-05-09 AU AU69264/94A patent/AU679075B2/en not_active Ceased
- 1994-05-09 WO PCT/EP1994/001492 patent/WO1994026747A1/en active IP Right Grant
- 1994-05-09 DK DK94917602T patent/DK0698025T3/da active
-
1995
- 1995-10-18 FI FI954965A patent/FI954965A/sv unknown
- 1995-11-13 NO NO954576A patent/NO305287B1/no not_active IP Right Cessation
-
1998
- 1998-01-28 GR GR980400178T patent/GR3026008T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE161259T1 (de) | 1998-01-15 |
ES2111930T3 (es) | 1998-03-16 |
DE69407407D1 (de) | 1998-01-29 |
JPH08510221A (ja) | 1996-10-29 |
CA2161783C (en) | 2006-08-15 |
FI954965A (sv) | 1995-11-10 |
NO954576L (no) | 1996-01-15 |
NO954576D0 (no) | 1995-11-13 |
NO305287B1 (no) | 1999-05-03 |
JP3439215B2 (ja) | 2003-08-25 |
AU679075B2 (en) | 1997-06-19 |
AU6926494A (en) | 1994-12-12 |
EP0698025A1 (en) | 1996-02-28 |
WO1994026747A1 (en) | 1994-11-24 |
GR3026008T3 (en) | 1998-04-30 |
EP0698025B1 (en) | 1997-12-17 |
FI954965A0 (sv) | 1995-10-18 |
DE69407407T2 (de) | 1998-04-09 |
NZ267081A (en) | 1997-11-24 |
CA2161783A1 (en) | 1994-11-24 |
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