DK0694539T3 - 7-O-ethere af taxanderivater - Google Patents

7-O-ethere af taxanderivater

Info

Publication number
DK0694539T3
DK0694539T3 DK95111843T DK95111843T DK0694539T3 DK 0694539 T3 DK0694539 T3 DK 0694539T3 DK 95111843 T DK95111843 T DK 95111843T DK 95111843 T DK95111843 T DK 95111843T DK 0694539 T3 DK0694539 T3 DK 0694539T3
Authority
DK
Denmark
Prior art keywords
alkyl
substituted
taxane derivatives
alkyloxy
cycloalkyl
Prior art date
Application number
DK95111843T
Other languages
English (en)
Inventor
Henry S Wong
Mark D Wittman
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK0694539T3 publication Critical patent/DK0694539T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
DK95111843T 1994-07-28 1995-07-27 7-O-ethere af taxanderivater DK0694539T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/282,129 US6201140B1 (en) 1994-07-28 1994-07-28 7-0-ethers of taxane derivatives

Publications (1)

Publication Number Publication Date
DK0694539T3 true DK0694539T3 (da) 2002-03-18

Family

ID=23080227

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95111843T DK0694539T3 (da) 1994-07-28 1995-07-27 7-O-ethere af taxanderivater

Country Status (10)

Country Link
US (1) US6201140B1 (da)
EP (1) EP0694539B1 (da)
JP (1) JPH08239373A (da)
AT (1) ATE209639T1 (da)
AU (1) AU688916B2 (da)
CA (1) CA2152771C (da)
DE (1) DE69524154T2 (da)
DK (1) DK0694539T3 (da)
ES (1) ES2167388T3 (da)
PT (1) PT694539E (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6040466A (en) * 1996-03-25 2000-03-21 Rhone Poulenc Rorer Sa Taxoids, their preparation and pharmaceutical compositions containing them
US6232477B1 (en) 1996-03-25 2001-05-15 Aventis Pharma S.A. Methods of preparing new taxoids and pharmaceutical compositions containing them
US6593482B2 (en) 1993-02-01 2003-07-15 Aventis Pharma S.A. Methods for preparing new taxoids and pharmaceutical compositions containing them
US6372780B2 (en) 1995-03-27 2002-04-16 Aventis Pharma S.A. Methods of treating cell lines expressing multidrug resistance P-glycoprotein
US5847170A (en) * 1995-03-27 1998-12-08 Rhone-Poulenc Rorer, S.A. Taxoids, their preparation and pharmaceutical compositions containing them
MA23823A1 (fr) 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
FR2745814B1 (fr) * 1996-03-06 1998-04-03 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US5902822A (en) * 1997-02-28 1999-05-11 Bristol-Myers Squibb Company 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
EP0933360A1 (en) 1997-12-22 1999-08-04 Pharmachemie B.V. Synthesis of new beta-lactams
US6156789A (en) * 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
US20040122081A1 (en) * 2002-11-08 2004-06-24 Gogate Uday Shankar Pharmaceutical compositions and methods of using taxane derivatives
AU2003290647A1 (en) * 2002-11-08 2004-06-03 Bristol-Myers Squibb Company Pharmaceutical compositions and methods of using taxane derivatives
CN102786502B (zh) * 2012-08-21 2014-05-14 江苏红豆杉生物科技有限公司 一种紫杉烷药物7,10-甲氧基多西他赛的合成方法
CN102775435B (zh) * 2012-08-21 2015-04-08 江苏红豆杉生物科技股份有限公司 一种用于制备7,10-甲氧基多西他赛的中间体的合成方法
CN104086514A (zh) * 2014-06-19 2014-10-08 上海应用技术学院 紫杉醇衍生物及其制备方法
CN113698369A (zh) * 2021-08-31 2021-11-26 无锡紫杉药业有限公司 一种除去卡巴他赛中特定单杂的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4814870A (en) 1987-08-05 1989-03-21 Compix Incorporated Portable infrared imaging apparatus
US4960790A (en) 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5175315A (en) 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5243045A (en) 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5227400A (en) 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
CA2098478C (en) 1991-09-23 1999-09-14 Robert A. Holton Preparation of substituted isoserine esters using metal alkoxides and .beta.-lactams
US5250683A (en) 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
DE69329304T2 (de) 1992-01-15 2001-01-04 Squibb & Sons Inc Enzymatische Verfahren zur Resolution von Enantiomeren-Mischungen nützlich wie Zwischenprodukte zur Herstellung von Taxanen
US5272171A (en) 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
CA2100808A1 (en) 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
CA2111527C (en) 1992-12-24 2000-07-18 Jerzy Golik Phosphonooxymethyl ethers of taxane derivatives
US9217093B1 (en) 2014-05-30 2015-12-22 Xerox Corporation Palladium ink compositions

Also Published As

Publication number Publication date
DE69524154D1 (de) 2002-01-10
ATE209639T1 (de) 2001-12-15
JPH08239373A (ja) 1996-09-17
CA2152771C (en) 2005-10-04
US6201140B1 (en) 2001-03-13
AU2721595A (en) 1996-02-08
EP0694539B1 (en) 2001-11-28
PT694539E (pt) 2002-05-31
DE69524154T2 (de) 2002-07-18
CA2152771A1 (en) 1996-01-29
EP0694539A1 (en) 1996-01-31
AU688916B2 (en) 1998-03-19
ES2167388T3 (es) 2002-05-16

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