DK0665834T3 - Quinolon- og acridinonderivater til behandling af urininkontinens - Google Patents

Quinolon- og acridinonderivater til behandling af urininkontinens

Info

Publication number
DK0665834T3
DK0665834T3 DK93922605T DK93922605T DK0665834T3 DK 0665834 T3 DK0665834 T3 DK 0665834T3 DK 93922605 T DK93922605 T DK 93922605T DK 93922605 T DK93922605 T DK 93922605T DK 0665834 T3 DK0665834 T3 DK 0665834T3
Authority
DK
Denmark
Prior art keywords
treatment
urinary incontinence
quinolone
acridinone
derivatives
Prior art date
Application number
DK93922605T
Other languages
Danish (da)
English (en)
Inventor
Cyrus John Ohnmacht
Diane Amy Trainor
Janet Marie Forst
Mark Morris Stein
Robert Joseph Harris
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9221989A external-priority patent/GB9221989D0/en
Priority claimed from GB939308065A external-priority patent/GB9308065D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK0665834T3 publication Critical patent/DK0665834T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30—Hydrogen technology
    • Y02E60/36—Hydrogen production from non-carbon containing sources, e.g. by water electrolysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK93922605T 1992-10-20 1993-10-14 Quinolon- og acridinonderivater til behandling af urininkontinens DK0665834T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9221989A GB9221989D0 (en) 1992-10-20 1992-10-20 Heterocyclic derivatives
GB939308065A GB9308065D0 (en) 1993-04-20 1993-04-20 Heterocyclic derivatives
PCT/GB1993/002125 WO1994008966A1 (en) 1992-10-20 1993-10-14 Quinolone and acridinone derivatives for the treatment of urinary incontinence

Publications (1)

Publication Number Publication Date
DK0665834T3 true DK0665834T3 (da) 2001-09-10

Family

ID=26301823

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93922605T DK0665834T3 (da) 1992-10-20 1993-10-14 Quinolon- og acridinonderivater til behandling af urininkontinens

Country Status (21)

Country Link
EP (1) EP0665834B1 (xx)
JP (1) JP3315699B2 (xx)
KR (1) KR100296657B1 (xx)
AT (1) ATE201671T1 (xx)
AU (1) AU673696B2 (xx)
CA (1) CA2146763C (xx)
DE (1) DE69330282T2 (xx)
DK (1) DK0665834T3 (xx)
ES (1) ES2160602T3 (xx)
FI (1) FI110940B (xx)
GB (2) GB9318935D0 (xx)
GR (1) GR3036442T3 (xx)
HK (1) HK1013996A1 (xx)
HU (2) HU215386B (xx)
IL (1) IL107287A (xx)
NO (1) NO303222B1 (xx)
NZ (1) NZ256719A (xx)
PT (1) PT665834E (xx)
RU (1) RU2124006C1 (xx)
TW (1) TW261616B (xx)
WO (1) WO1994008966A1 (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407432D0 (en) * 1994-04-14 1994-06-08 Zeneca Ltd Heterocyclic derivative
GB9707695D0 (en) * 1996-08-07 1997-06-04 Hoffmann La Roche Tricyclic dione derivatives
US6265417B1 (en) 1997-12-18 2001-07-24 Abbott Laboratories Potassium channel openers
TR200001715T2 (tr) * 1997-12-18 2000-12-21 Abbott Laboratories Potasyum kanalı açıcıları.
US6593335B1 (en) 1997-12-18 2003-07-15 Abbott Laboratories Potassium channel openers
US6642222B2 (en) * 1998-10-28 2003-11-04 Abbott Laboratories Pyrano, piperidino, and thiopyrano compounds and methods of use
US6191140B1 (en) 1998-10-28 2001-02-20 Abbott Laboratories Pyrano, piperidino, and thiopyrano compounds and methods of use
EP1131322A2 (en) * 1998-10-28 2001-09-12 Abbott Laboratories Dihydropyridine compounds and methods of use
US6518279B2 (en) 1999-03-04 2003-02-11 Abbott Laboratories Cyclopentanone dihydropyridine compounds useful as potassium channel openers
ES2266237T3 (es) 2000-08-02 2007-03-01 Astrazeneca Ab Procedimiento de sintesis de cetonas alfa-beta insaturadas.
DE60131660D1 (de) 2000-08-02 2008-01-10 Astrazeneca Ab Verfahren zur asymetrischen synthese von substituierten 1,4-dihydropyridin-derivaten
FR2856687B1 (fr) * 2003-06-25 2005-09-16 Servier Lab Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN101171234B (zh) 2005-05-04 2011-11-16 欧加农股份有限公司 二氢吡啶衍生物
UA92009C2 (ru) * 2005-05-04 2010-09-27 Н.В. Органон Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия
UA92007C2 (ru) * 2005-05-04 2010-09-27 Н.В. Органон Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности
UA92008C2 (xx) * 2005-05-04 2010-09-27 Н.В. Органон 4-феніл-5-оксо-1,4,5,6,7,8-гексагідрохінолінпохідні для лікування безплідності$4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолинпроизводные для лечения бесплодия
WO2006122156A2 (en) * 2005-05-09 2006-11-16 Hydra Biosciences, Inc. Compounds for modulating trpv3 function
US8916550B2 (en) 2005-05-09 2014-12-23 Hydra Biosciences, Inc. Compounds for modulating TRPV3 function
US11976041B1 (en) 2023-10-23 2024-05-07 King Faisal University 9-(5-bromo-2-hydroxyphenyl)-10-[3-(dimethylamino)propyl]-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione as an antimicrobial compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2003148A1 (de) * 1970-01-24 1971-07-29 Bayer Ag Neue 1,4-Dihydropyridinderivate
DE2018738A1 (en) * 1970-04-18 1971-10-28 Farbenfabriken Bayer Ag, 5090 Leverkusen Hydrogenated pyridines, quinolines andacridi
GB9220570D0 (en) * 1991-10-21 1992-11-11 Ici Plc Therapeutic agent
CA2080949A1 (en) * 1991-10-21 1993-04-22 Cyrus John Ohnmacht Therapeutic agents

Also Published As

Publication number Publication date
CA2146763C (en) 2005-10-04
CA2146763A1 (en) 1994-04-28
FI951858A (fi) 1995-04-19
AU5154593A (en) 1994-05-09
WO1994008966A1 (en) 1994-04-28
GB9319938D0 (en) 1993-11-17
ES2160602T3 (es) 2001-11-16
DE69330282D1 (de) 2001-07-05
ATE201671T1 (de) 2001-06-15
RU95110937A (ru) 1997-03-10
NZ256719A (en) 1996-11-26
IL107287A0 (en) 1994-01-25
NO303222B1 (no) 1998-06-15
NO951484L (no) 1995-06-19
AU673696B2 (en) 1996-11-21
HK1013996A1 (en) 1999-09-17
IL107287A (en) 2000-09-28
NO951484D0 (no) 1995-04-19
GR3036442T3 (en) 2001-11-30
TW261616B (xx) 1995-11-01
FI951858A0 (fi) 1995-04-19
EP0665834A1 (en) 1995-08-09
FI110940B (fi) 2003-04-30
JP3315699B2 (ja) 2002-08-19
HU211741A9 (en) 1995-12-28
RU2124006C1 (ru) 1998-12-27
HU215386B (hu) 1998-12-28
HUT70026A (en) 1995-09-28
EP0665834B1 (en) 2001-05-30
HU9302933D0 (en) 1993-12-28
KR100296657B1 (ko) 2001-10-24
GB9318935D0 (en) 1993-10-27
PT665834E (pt) 2001-11-30
JPH08502282A (ja) 1996-03-12
DE69330282T2 (de) 2002-01-10

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