DK0644768T3 - Fremgangsmåder og præparater til inhibering af endotelcelle- og fibrinogenfremkaldt inflammation - Google Patents

Fremgangsmåder og præparater til inhibering af endotelcelle- og fibrinogenfremkaldt inflammation

Info

Publication number
DK0644768T3
DK0644768T3 DK93916500T DK93916500T DK0644768T3 DK 0644768 T3 DK0644768 T3 DK 0644768T3 DK 93916500 T DK93916500 T DK 93916500T DK 93916500 T DK93916500 T DK 93916500T DK 0644768 T3 DK0644768 T3 DK 0644768T3
Authority
DK
Denmark
Prior art keywords
fibrinogen
methods
endothelial cell
preparations
binding
Prior art date
Application number
DK93916500T
Other languages
Danish (da)
English (en)
Inventor
Lucia R Languino
Dario C Altieri
Edward F Plow
John E Geltosky
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK0644768T3 publication Critical patent/DK0644768T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93916500T 1992-06-11 1993-06-11 Fremgangsmåder og præparater til inhibering af endotelcelle- og fibrinogenfremkaldt inflammation DK0644768T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89811792A 1992-06-11 1992-06-11
PCT/US1993/005610 WO1993025218A1 (fr) 1992-06-11 1993-06-11 Procedes et compositions d'inhibition d'inflammations provoquees par des cellules endotheliales et par le fibrinogene

Publications (1)

Publication Number Publication Date
DK0644768T3 true DK0644768T3 (da) 2002-05-21

Family

ID=25408971

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93916500T DK0644768T3 (da) 1992-06-11 1993-06-11 Fremgangsmåder og præparater til inhibering af endotelcelle- og fibrinogenfremkaldt inflammation

Country Status (9)

Country Link
EP (1) EP0644768B1 (fr)
AT (1) ATE209040T1 (fr)
AU (1) AU675073B2 (fr)
CA (1) CA2137813A1 (fr)
DE (1) DE69331193T2 (fr)
DK (1) DK0644768T3 (fr)
ES (1) ES2165366T3 (fr)
PT (1) PT644768E (fr)
WO (1) WO1993025218A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60042069D1 (de) * 1999-06-24 2009-06-04 Univ Johns Hopkins Zusammensetzungen und methoden zur vorbeugung transepithelialer übertragung von hiv
US9901625B2 (en) 2011-10-15 2018-02-27 University Of Maryland, College Park Methods of regulating uptake and transcellular transport of leukocytes and therapeutics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3203775A1 (de) * 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
KR900701846A (ko) * 1988-09-28 1990-12-04 원본미기재 세포간 점착분자 및 이의 결합 리간드
US5473051A (en) * 1990-07-19 1995-12-05 The Scripps Research Institute Inhibition of Mac-1 receptor binding to fibrinogen using D30 homologs

Also Published As

Publication number Publication date
EP0644768A4 (fr) 1997-06-11
AU4632793A (en) 1994-01-04
AU675073B2 (en) 1997-01-23
DE69331193D1 (de) 2002-01-03
EP0644768B1 (fr) 2001-11-21
CA2137813A1 (fr) 1993-12-23
ES2165366T3 (es) 2002-03-16
DE69331193T2 (de) 2002-04-18
WO1993025218A1 (fr) 1993-12-23
PT644768E (pt) 2002-03-28
EP0644768A1 (fr) 1995-03-29
ATE209040T1 (de) 2001-12-15

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