DE60042069D1 - Zusammensetzungen und methoden zur vorbeugung transepithelialer übertragung von hiv - Google Patents

Zusammensetzungen und methoden zur vorbeugung transepithelialer übertragung von hiv

Info

Publication number
DE60042069D1
DE60042069D1 DE60042069T DE60042069T DE60042069D1 DE 60042069 D1 DE60042069 D1 DE 60042069D1 DE 60042069 T DE60042069 T DE 60042069T DE 60042069 T DE60042069 T DE 60042069T DE 60042069 D1 DE60042069 D1 DE 60042069D1
Authority
DE
Germany
Prior art keywords
transmission
icam
hiv
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60042069T
Other languages
English (en)
Inventor
Richard B Markham
Kristen V Khanna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Application granted granted Critical
Publication of DE60042069D1 publication Critical patent/DE60042069D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE60042069T 1999-06-24 2000-06-23 Zusammensetzungen und methoden zur vorbeugung transepithelialer übertragung von hiv Expired - Lifetime DE60042069D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14069899P 1999-06-24 1999-06-24
PCT/US2000/017293 WO2000079010A1 (en) 1999-06-24 2000-06-23 Compositions and methods for preventing transepithelial transmission of hiv

Publications (1)

Publication Number Publication Date
DE60042069D1 true DE60042069D1 (de) 2009-06-04

Family

ID=22492418

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60042069T Expired - Lifetime DE60042069D1 (de) 1999-06-24 2000-06-23 Zusammensetzungen und methoden zur vorbeugung transepithelialer übertragung von hiv

Country Status (11)

Country Link
US (1) US6566095B1 (de)
EP (1) EP1190101B1 (de)
JP (1) JP4880153B2 (de)
CN (2) CN101912610A (de)
AT (1) ATE429518T1 (de)
AU (1) AU777241B2 (de)
CA (1) CA2377479C (de)
DE (1) DE60042069D1 (de)
DK (1) DK1190101T3 (de)
HK (1) HK1047300A1 (de)
WO (1) WO2000079010A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2428753C (en) * 2000-11-17 2013-05-21 Idenix (Cayman) Limited Methods for inhibiting the transmission of hiv using topically applied substituted 6-benzyl-4-oxopyrimidines
WO2006004903A2 (en) * 2004-06-28 2006-01-12 Atherogenics, Inc. 1,2-bis-(substituted-phenyl)-2-propen-1-ones and pharmaceutical compositions thereof
AU2006304382A1 (en) 2005-10-14 2007-04-26 The Johns Hopkins School Of Medicine Reduction and prevention of cell-associated HIV transepithelial migration, microbides and other formulations and methods
RU2594249C2 (ru) * 2010-04-09 2016-08-10 Иммурон Лимитед Способы и композиции для предотвращения передачи вич-инфекции
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
US20120100186A1 (en) * 2010-10-20 2012-04-26 Washington University Nanoparticulate-based contraceptive/anti-hiv composition and methods
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284931A (en) 1987-05-04 1994-02-08 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
ATE146968T1 (de) 1989-03-16 1997-01-15 Blood Res Center Verwendung von funkionellen derivaten des interzellulär-adhäsions-moleküls icam-1 in einer antivirus-therapie
WO1990013281A2 (en) 1989-04-28 1990-11-15 Baylor College Of Medicine Method of suppressing hiv infection
ZA903223B (en) 1989-04-28 1991-02-27 Baylor College Medicine Dissemination of hiv-1 infected cells
US5324510A (en) 1989-09-01 1994-06-28 Boehringer Ingelheim Pharmaceuticals, Inc. Use of antibodies to intercellular adhesion molecule-1 (ICAM-1) in the treatment of asthma
GB9009548D0 (en) 1990-04-27 1990-06-20 Celltech Ltd Chimeric antibody and method
GB9009549D0 (en) 1990-04-27 1990-06-20 Celltech Ltd Recombinant antibody and method
WO1991018010A1 (en) 1990-05-15 1991-11-28 Swinburne Limited Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
US5674982A (en) * 1990-07-20 1997-10-07 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5629162A (en) * 1991-06-11 1997-05-13 The Center For Blood Research Method of identifying agents which modulate ICAM-3 binding to LFA-1
US5532127A (en) 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
WO1993014776A1 (en) 1992-01-27 1993-08-05 Icos Corporation Icam-related protein
US5525487A (en) 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
WO1993025218A1 (en) * 1992-06-11 1993-12-23 The Scripps Research Institute Methods and compositions for inhibiting endothelial cell and fibrinogen mediated inflammation
US5651970A (en) 1993-03-19 1997-07-29 Allen; Allen D. Method for inhibiting disease associated with the human immunodeficiency virus through the use of monoclonal antibodies directed against anti-self cytotoxic T-lymphocytes or their lytics
US5733540A (en) 1995-03-08 1998-03-31 Lee; Peter Poon-Hang Protection from viral infection via colonization of mucosal membranes with genetically modified bacteria

Also Published As

Publication number Publication date
AU5885500A (en) 2001-01-09
WO2000079010A1 (en) 2000-12-28
ATE429518T1 (de) 2009-05-15
EP1190101B1 (de) 2009-04-22
CN101912610A (zh) 2010-12-15
EP1190101A1 (de) 2002-03-27
CN1402797A (zh) 2003-03-12
CA2377479C (en) 2011-01-11
JP4880153B2 (ja) 2012-02-22
JP2003513007A (ja) 2003-04-08
EP1190101A4 (de) 2004-09-15
US6566095B1 (en) 2003-05-20
CA2377479A1 (en) 2000-12-28
AU777241B2 (en) 2004-10-07
DK1190101T3 (da) 2009-08-03
HK1047300A1 (zh) 2003-02-14

Similar Documents

Publication Publication Date Title
UA88463C2 (ru) Фармацевтическая композиция, которая содержит соединение 1, и процесс лечения вич-инфекции
TR200003011T2 (tr) Yeni dihidropirimidinler.
DE60000823D1 (de) Methoden zur verhütung von kristallwachstum und partikelaggregation in nanopartikelzusammensetzungen
DK1157037T3 (da) GCSF-konjugater
TR200002299T2 (tr) Epotilon kompozisyonları.
IL143512A (en) Azabicycloalkanes, pharmaceuticals including them and their use in the manufacture of drugs for the prevention or treatment of infection by the immunodeficiency virus
IL140710A0 (en) Pulmonary delivery of active agents
ATE296094T1 (de) Stickstoffmonoxid bildende zusammensetzungen zur behandlung von nagelbettinfektionen
DE69838986D1 (de) Polypeptide, deren herstellung und verwendung
TW200607798A (en) Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof
TR200200795T2 (tr) 5-HT1B antagonistleri olarak piperazin türevleri
RS50044B (sr) Polimorfni oblici telmisartana, postupak za njihovo pripremanje i njihova primena za pripremanje leka
ES2165269A1 (es) Derivados de alfa-cetoamidas.
EE200100009A (et) Bensimidasoolid, nende valmistamine ja kasutamineravimitena
DE69932510D1 (de) Vaskularisierungsinhibitoren
EP0220696A3 (en) Use of buspirone for preparing pharmaceutical compositions for alleviation of panic disorders
IT1302682B1 (it) Composizioni farmaceutiche orali contenenti buprenorfina
DE69928779D1 (de) Nichtnukleoside reverse transkriptase-hemmer zur behandlung von hiv-infektion
DE69911023D1 (de) Antagonisten des gonadotropin freisetzenden hormons
ATE429518T1 (de) Zusammensetzungen und methoden zur vorbeugung transepithelialer übertragung von hiv
AR026637A1 (es) Virus atenuados e inocuos de la diarrea virica bovina para uso en vacas gestantes
PT1107793E (pt) Conjugados de dextrano-leptina, composicoes farmaceuticas e processos relacionados
ATE342734T1 (de) Adenosin a1 antagonisten gegen männliche sterilität
ATE412404T1 (de) Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon
ATE278461T1 (de) Mikropartikel hergestellt aus cycloolefincopolymeren und deren verwendung zur kontrollierten wirkstofffreigabe

Legal Events

Date Code Title Description
8364 No opposition during term of opposition