DK0630369T3 - Anthelmintiske benzimidazolmidler - Google Patents

Anthelmintiske benzimidazolmidler

Info

Publication number
DK0630369T3
DK0630369T3 DK93904008.5T DK93904008T DK0630369T3 DK 0630369 T3 DK0630369 T3 DK 0630369T3 DK 93904008 T DK93904008 T DK 93904008T DK 0630369 T3 DK0630369 T3 DK 0630369T3
Authority
DK
Denmark
Prior art keywords
pct
alkyl
sec
date
benzimidazole agents
Prior art date
Application number
DK93904008.5T
Other languages
Danish (da)
English (en)
Inventor
Bernard Joseph Banks
Christopher James Dutton
Alexander Crossan Goudie
Original Assignee
Pfizer
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer, Pfizer Ltd filed Critical Pfizer
Application granted granted Critical
Publication of DK0630369T3 publication Critical patent/DK0630369T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
DK93904008.5T 1992-03-12 1993-02-23 Anthelmintiske benzimidazolmidler DK0630369T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929205368A GB9205368D0 (en) 1992-03-12 1992-03-12 Benzimidozole anthelmintic agents

Publications (1)

Publication Number Publication Date
DK0630369T3 true DK0630369T3 (da) 1997-10-13

Family

ID=10711969

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93904008.5T DK0630369T3 (da) 1992-03-12 1993-02-23 Anthelmintiske benzimidazolmidler

Country Status (11)

Country Link
US (1) US5468765A (el)
EP (1) EP0630369B1 (el)
JP (1) JP2758989B2 (el)
AT (1) ATE154014T1 (el)
CA (1) CA2130665C (el)
DE (1) DE69311318T2 (el)
DK (1) DK0630369T3 (el)
ES (1) ES2104128T3 (el)
GB (1) GB9205368D0 (el)
GR (1) GR3024109T3 (el)
WO (1) WO1993018010A1 (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ335166A (en) † 1999-04-14 2001-11-30 Ashmont Holdings Ltd Anthelmintic composition containing triclabendazole in at least one solvent
CH684792A5 (de) * 1993-02-10 1994-12-30 Von Roll Ag Verfahren zum Gewinnen von Glas und Metall aus in Müllverbrennungsanlagen anfallenden festen Rückständen.
AU741772B2 (en) 1997-02-25 2001-12-06 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Substituted benzimidazoles as non-nucleoside inhibitors of reverse transcriptase
WO2001095723A1 (en) * 2000-06-15 2001-12-20 Ssl International Plc Parasiticidal composition
DE602005021054D1 (de) * 2004-02-03 2010-06-17 Wyeth Llc Wurmmittel
WO2010042395A1 (en) * 2008-10-08 2010-04-15 Wyeth Llc Benzimidazole anthelmintic compositions
AU2010224685A1 (en) 2009-03-18 2011-11-03 Fidopharm, Inc. Parasiticidal formulation
EP3235815A1 (de) 2016-04-19 2017-10-25 Philipps-Universität Marburg Wirkstoffe gegen parasitäre helminthen

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2253324A1 (de) * 1972-10-31 1974-05-09 Bayer Ag 1-alkoxycarbonyl-2- eckige klammer auf bis-(alkoxycarbonyl)-amino eckige klammer zu -benzimidazole, verfahren zu ihrer herstellung, sowie ihre verwendung als fungizide
US3929821A (en) * 1972-12-29 1975-12-30 Syntex Inc 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives
US4002640A (en) * 1972-12-29 1977-01-11 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
JPS4975729A (el) * 1973-10-31 1974-07-22
US3915986A (en) * 1974-06-19 1975-10-28 Smithkline Corp Methyl 5-propylthio-2-benzimidazolecarbamate
FR2306633A1 (fr) * 1975-04-11 1976-11-05 Ugine Kuhlmann Nouveaux melanges fongicides
US4512998A (en) * 1980-10-20 1985-04-23 Schering Corporation Anthelmintic benzimidazole carbamates
US4435418A (en) * 1982-12-13 1984-03-06 Smithkline Beckman Corporation 5-Phenylethenylbenzimidazoles
US4826841A (en) * 1985-04-05 1989-05-02 Eli Lilly And Company Alkanoyl anilides as pesticides
US4826862A (en) * 1988-02-12 1989-05-02 Janssen Pharmaceutica, N.V. Anthelminthic [(5(6) (1H-azole-1-ylmethyl)benzimidazole]carbamates
NZ232785A (en) * 1989-03-15 1991-03-26 Janssen Pharmaceutica Nv 5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions
GB9115273D0 (en) * 1991-07-15 1991-08-28 Pfizer Ltd Benzimidazole anthelmintics
GB9115272D0 (en) * 1991-07-15 1991-08-28 Pfizer Ltd Benzimidazole anthelmintics

Also Published As

Publication number Publication date
CA2130665C (en) 1998-09-22
US5468765A (en) 1995-11-21
EP0630369B1 (en) 1997-06-04
GB9205368D0 (en) 1992-04-22
ES2104128T3 (es) 1997-10-01
EP0630369A1 (en) 1994-12-28
JPH07500612A (ja) 1995-01-19
DE69311318T2 (de) 1997-09-25
DE69311318D1 (de) 1997-07-10
WO1993018010A1 (en) 1993-09-16
JP2758989B2 (ja) 1998-05-28
GR3024109T3 (en) 1997-10-31
ATE154014T1 (de) 1997-06-15
CA2130665A1 (en) 1993-09-13

Similar Documents

Publication Publication Date Title
FI915282A (fi) Mono-n-substituerade 1,4,7,10-tetra -azacyklododekanderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska aemnen.
DK0630369T3 (da) Anthelmintiske benzimidazolmidler
DK0775132T3 (da) (Azetidin-1-ylalkyl)lactamer som tachykininantagonister
ATE161252T1 (de) Antivirale und antihypertensive verbindungen
KR960701881A (ko) 나프탈렌포스폰산의 우레이도 유도체 및 이의 제조 방법(Ureido derivatives of naphtha1enephosphonic acids and process for their preparation)
CO5640129A2 (es) Agonistas del receptor activado por proliferador de peroxisoma
ATE173730T1 (de) N-(piperidinyl-1-alkyl)-substituierte cyclohexancarbonsäureamide als 5ht1a rezeptor antagonisten
FI920349A0 (fi) Foerfarande foer framstaellning av nya tetrazolderivat och deras anvaendning.
FI943931A0 (fi) Indolijohdannaisia steroidi-5alfa-reduktaasin inhibiittoreina
ATE106875T1 (de) Heteroaryl-3-oxo-propan-nitril-derivat verwendbar in erregung von myelopoiesis.
KR890009867A (ko) 비 펩타이드성 레닌 억제제
FI924934A0 (fi) Nya ftalaziner som innehaoller en eter- eller tioetergruppering i 1-staellning och foerfarande foer deras framstaellning
NZ237379A (en) Substituted urea derivatives and pharmaceutical compositions
DE59401952D1 (de) Isatinderivate zum färben von keratinhaltigen fasern
NO924076L (no) Antihypertensive midler
ATE172724T1 (de) Anthelmintische benzimidazole
DE69131774D1 (de) Antibakterielle penem-ester derivate
DK0623118T3 (da) Carbamatderivater og deres anvendelse i medicin
KR970701542A (ko) 안압 저하제(ocular tension depressant)
DE59301421D1 (de) Amphiphile nucleosidphosphatanaloga