DK0623586T3 - Process for the preparation of 2- (1-cyclohexenyl) ethylamine - Google Patents

Process for the preparation of 2- (1-cyclohexenyl) ethylamine

Info

Publication number
DK0623586T3
DK0623586T3 DK94106841.3T DK94106841T DK0623586T3 DK 0623586 T3 DK0623586 T3 DK 0623586T3 DK 94106841 T DK94106841 T DK 94106841T DK 0623586 T3 DK0623586 T3 DK 0623586T3
Authority
DK
Denmark
Prior art keywords
cyclohexenyl
ethylamine
preparation
dextromethorphan
phenylethylamine
Prior art date
Application number
DK94106841.3T
Other languages
Danish (da)
Inventor
David L Dr Kuo
Martin Dr Eyer
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Application granted granted Critical
Publication of DK0623586T3 publication Critical patent/DK0623586T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/70—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by reduction of unsaturated amines
    • C07C209/72—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by reduction of unsaturated amines by reduction of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Secondary Cells (AREA)
  • Catalysts (AREA)
  • Battery Electrode And Active Subsutance (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A novel process for the preparation of 2-(1-cyclohexenyl)ethylamine by reduction of 2-phenylethylamine with lithium in the presence of a primary or secondary aliphatic alkylamine is described. 2-(1-Cyclohexenyl)ethylamine can be used as a starting material for the preparation of dextromethorphan, a cough-relieving pharmaceutical.
DK94106841.3T 1993-05-03 1994-05-02 Process for the preparation of 2- (1-cyclohexenyl) ethylamine DK0623586T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH134993A CH685941A5 (en) 1993-05-03 1993-05-03 A process for preparing 2- (1-cyclohexenyl) ethylamine.

Publications (1)

Publication Number Publication Date
DK0623586T3 true DK0623586T3 (en) 1996-05-13

Family

ID=4208402

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94106841.3T DK0623586T3 (en) 1993-05-03 1994-05-02 Process for the preparation of 2- (1-cyclohexenyl) ethylamine

Country Status (12)

Country Link
EP (1) EP0623586B1 (en)
JP (1) JPH06312960A (en)
AT (1) ATE136291T1 (en)
CA (1) CA2121524A1 (en)
CH (1) CH685941A5 (en)
DE (1) DE59400178D1 (en)
DK (1) DK0623586T3 (en)
ES (1) ES2085808T3 (en)
GR (1) GR3019593T3 (en)
IL (1) IL109479A (en)
MX (1) MX9403062A (en)
TW (1) TW322467B (en)

Also Published As

Publication number Publication date
TW322467B (en) 1997-12-11
GR3019593T3 (en) 1996-07-31
IL109479A (en) 1997-09-30
IL109479A0 (en) 1994-07-31
JPH06312960A (en) 1994-11-08
MX9403062A (en) 1995-01-31
EP0623586B1 (en) 1996-04-03
EP0623586A1 (en) 1994-11-09
CA2121524A1 (en) 1994-11-04
DE59400178D1 (en) 1996-05-09
CH685941A5 (en) 1995-11-15
ES2085808T3 (en) 1996-06-01
ATE136291T1 (en) 1996-04-15

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Legal Events

Date Code Title Description
ATS Application withdrawn