DK0623347T3 - Anvendelse af bisphosphonsyrederivater til fremstilling af et lægemiddel til fremme af knogleheling - Google Patents

Anvendelse af bisphosphonsyrederivater til fremstilling af et lægemiddel til fremme af knogleheling

Info

Publication number
DK0623347T3
DK0623347T3 DK94400719T DK94400719T DK0623347T3 DK 0623347 T3 DK0623347 T3 DK 0623347T3 DK 94400719 T DK94400719 T DK 94400719T DK 94400719 T DK94400719 T DK 94400719T DK 0623347 T3 DK0623347 T3 DK 0623347T3
Authority
DK
Denmark
Prior art keywords
amino
acid derivatives
bisphosphonic acid
promoting bone
medicament
Prior art date
Application number
DK94400719T
Other languages
Danish (da)
English (en)
Inventor
Frederic Lacheretz
Alain Barbier
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9445758&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0623347(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Application granted granted Critical
Publication of DK0623347T3 publication Critical patent/DK0623347T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
DK94400719T 1993-04-05 1994-04-01 Anvendelse af bisphosphonsyrederivater til fremstilling af et lægemiddel til fremme af knogleheling DK0623347T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9303999A FR2703590B1 (fr) 1993-04-05 1993-04-05 Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .

Publications (1)

Publication Number Publication Date
DK0623347T3 true DK0623347T3 (da) 2002-02-11

Family

ID=9445758

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94400719T DK0623347T3 (da) 1993-04-05 1994-04-01 Anvendelse af bisphosphonsyrederivater til fremstilling af et lægemiddel til fremme af knogleheling

Country Status (17)

Country Link
US (1) US5488041A (no)
EP (1) EP0623347B1 (no)
JP (1) JP3062001B2 (no)
CN (1) CN1062735C (no)
AT (1) ATE207752T1 (no)
AU (1) AU680229B2 (no)
CA (1) CA2120538C (no)
DE (1) DE69428827T2 (no)
DK (1) DK0623347T3 (no)
ES (1) ES2166771T3 (no)
FR (1) FR2703590B1 (no)
HU (1) HU220764B1 (no)
IL (1) IL109212A (no)
NO (1) NO305304B1 (no)
NZ (1) NZ260244A (no)
PT (1) PT623347E (no)
ZA (1) ZA942358B (no)

Families Citing this family (39)

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US6406714B1 (en) 1992-12-02 2002-06-18 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids
US5591730A (en) * 1993-10-12 1997-01-07 The Regents Of The University Of California Inhibition of urinary calculi growth
US20010007863A1 (en) 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
TW390813B (en) * 1994-04-29 2000-05-21 Merck & Co Inc Wet granulation formulation for bisphosphonic acids
US5462932A (en) * 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
AU5973496A (en) * 1995-06-06 1996-12-24 Merck & Co., Inc. Bisphosphonate cement composition to prevent aseptic loosening of orthopedic implant devices
EP0753523A1 (en) * 1995-07-10 1997-01-15 Gador S.A. Amino-substituted bisphosphonic acids
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
PL332496A1 (en) * 1996-10-04 1999-09-13 Merck & Co Inc Liquid alendronate preparations
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US6432932B1 (en) 1997-07-22 2002-08-13 Merck & Co., Inc. Method for inhibiting bone resorption
US5994329A (en) * 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
US6015801A (en) * 1997-07-22 2000-01-18 Merck & Co., Inc. Method for inhibiting bone resorption
US8586781B2 (en) 1998-04-02 2013-11-19 Mbc Pharma, Inc. Bone targeted therapeutics and methods of making and using the same
US6750340B2 (en) 1998-04-02 2004-06-15 Mbc Research, Inc. Bisphosphonate conjugates and methods of making and using the same
US7598246B2 (en) * 1998-04-02 2009-10-06 Mbc Pharma, Inc. Bisphosphonate conjugates and methods of making and using the same
US6896871B2 (en) 1998-04-02 2005-05-24 Mbc Research, Inc. Biphosphonate conjugates and methods of making and using the same
GB2336311A (en) * 1998-04-15 1999-10-20 Merck & Co Inc Bisphosphonate Dosing Regimen
FR2784031B1 (fr) * 1998-10-02 2002-02-01 Sanofi Elf Utilisation de derives de l'acide bisphosphonique pour la preparation d'un medicament destine au traitement des boiteries
FR2803520B1 (fr) * 2000-01-12 2002-09-20 Ceva Sante Animale Procede pour augmenter la production d'oeufs et consolider la coquille des oeufs chez les volailles
EP1136069A1 (en) * 2000-03-21 2001-09-26 SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. Pharmaceutical compositions containing clodronates for high local tolerance intramuscular administration
CA2347330C (en) * 2001-05-10 2002-03-12 Pharmaceutical Partners Of Canada Inc. Liquid injectable formulation of disodium pamidronate
AU2002360619B2 (en) * 2001-12-21 2006-10-05 Allergan Pharmaceuticals International Limited Method for the treatment of bone disorders
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
WO2003086415A1 (en) * 2002-04-05 2003-10-23 Merck & Co., Inc. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
CN100551377C (zh) 2002-05-10 2009-10-21 弗·哈夫曼-拉罗切有限公司 用于治疗和预防骨质疏松症的二膦酸
US20040137058A1 (en) * 2002-07-09 2004-07-15 Katdare Ashok V. Effervescent bisphosphonate formulation
US20040138180A1 (en) * 2002-10-03 2004-07-15 Barr Laboratories, Inc. Bisphosphonate composition and process for the preparation thereof
PL212072B1 (pl) * 2002-12-20 2012-08-31 Hoffmann La Roche Tabletka zawierająca jako substancję czynną do 250 mg kwasu ibandronowego oraz sposób jej wytwarzania
ITMI20040218A1 (it) * 2004-02-10 2004-05-10 Abiogen Pharma Spa Uso di neridronato sodico per promuovere la neoformazione ossea
US20050261250A1 (en) * 2004-05-19 2005-11-24 Merck & Co., Inc., Compositions and methods for inhibiting bone resorption
KR100564628B1 (ko) * 2004-06-16 2006-03-28 삼성전자주식회사 스플릿 게이트형 플래쉬 메모리 소자 및 그 제조방법
WO2006018033A1 (en) * 2004-08-20 2006-02-23 Mepha Ag Formulations of bisphosphonates
US8071574B2 (en) * 2005-02-22 2011-12-06 John Dennis Bobyn Implant improving local bone formation
US20070087052A1 (en) * 2005-10-19 2007-04-19 Katdare Ashok V Effervescent bisphosphonate formulation
EP1923049A1 (en) * 2006-11-17 2008-05-21 Besins Healthcare Pharmaceutical compositions comprising a bisphosphonate compound
FR2954320B1 (fr) 2009-12-17 2012-06-15 Cll Pharma Composition pharmaceutique orale suprabiodisponible contenant un acide biphosphonique ou un de ses sels
US8882740B2 (en) * 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone
RU2640582C2 (ru) 2011-08-01 2018-01-10 Мбс Фарма, Инк. Производные витамина в6 нуклеотидов, ациклических нуклеотидов и ациклических нуклеозидных фосфонатов

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194748B (it) * 1981-02-12 1988-09-28 Gentili Ist Spa Composizioni farmaceutiche per il trattamento di osteopatie
FR2531088B1 (fr) * 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
GB8419489D0 (en) * 1984-07-31 1984-09-05 Leo Pharm Prod Ltd Chemical compounds
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
GB8530603D0 (en) * 1985-12-12 1986-01-22 Leo Pharm Prod Ltd Chemical compounds
CA1339805C (en) * 1988-01-20 1998-04-07 Yasuo Isomura (cycloalkylamino)methylenebis(phosphonic acid) and medicines containing the same as an active
FR2629716B1 (fr) * 1988-04-07 1991-07-19 Sanofi Sa Composition pharmaceutique pour administration orale a base d'un derive d'acide diphosphonique
US4922007A (en) * 1989-06-09 1990-05-01 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
US5270365A (en) * 1991-12-17 1993-12-14 Merck & Co., Inc. Prevention and treatment of periodontal disease with alendronate
EP0600834A1 (en) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery

Also Published As

Publication number Publication date
JP3062001B2 (ja) 2000-07-10
ATE207752T1 (de) 2001-11-15
AU680229B2 (en) 1997-07-24
CN1062735C (zh) 2001-03-07
DE69428827D1 (de) 2001-12-06
JPH0748261A (ja) 1995-02-21
FR2703590A1 (fr) 1994-10-14
IL109212A (en) 2001-07-24
EP0623347B1 (fr) 2001-10-31
HU9400967D0 (en) 1994-06-28
DE69428827T2 (de) 2002-07-18
CA2120538A1 (en) 1994-10-06
FR2703590B1 (fr) 1995-06-30
US5488041A (en) 1996-01-30
PT623347E (pt) 2002-03-28
HU220764B1 (hu) 2002-05-28
HUT68310A (en) 1995-06-28
NO305304B1 (no) 1999-05-10
ZA942358B (en) 1995-10-05
CA2120538C (en) 1999-02-23
NZ260244A (en) 1997-06-24
EP0623347A1 (fr) 1994-11-09
ES2166771T3 (es) 2002-05-01
CN1104091A (zh) 1995-06-28
IL109212A0 (en) 1994-07-31
NO941185L (no) 1994-10-06
NO941185D0 (no) 1994-03-30
AU5910294A (en) 1994-10-06

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