ATE207752T1 - Verwendung von bisphosphorsäurederivaten zur herstellung eines medikamentes zur förderung der knochenheilung - Google Patents

Verwendung von bisphosphorsäurederivaten zur herstellung eines medikamentes zur förderung der knochenheilung

Info

Publication number
ATE207752T1
ATE207752T1 AT94400719T AT94400719T ATE207752T1 AT E207752 T1 ATE207752 T1 AT E207752T1 AT 94400719 T AT94400719 T AT 94400719T AT 94400719 T AT94400719 T AT 94400719T AT E207752 T1 ATE207752 T1 AT E207752T1
Authority
AT
Austria
Prior art keywords
amino
acid derivatives
medication
produce
promote bone
Prior art date
Application number
AT94400719T
Other languages
English (en)
Inventor
Alain Barbier
Frederic Lacheretz
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9445758&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE207752(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Application granted granted Critical
Publication of ATE207752T1 publication Critical patent/ATE207752T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
AT94400719T 1993-04-05 1994-04-01 Verwendung von bisphosphorsäurederivaten zur herstellung eines medikamentes zur förderung der knochenheilung ATE207752T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9303999A FR2703590B1 (fr) 1993-04-05 1993-04-05 Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .

Publications (1)

Publication Number Publication Date
ATE207752T1 true ATE207752T1 (de) 2001-11-15

Family

ID=9445758

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94400719T ATE207752T1 (de) 1993-04-05 1994-04-01 Verwendung von bisphosphorsäurederivaten zur herstellung eines medikamentes zur förderung der knochenheilung

Country Status (17)

Country Link
US (1) US5488041A (de)
EP (1) EP0623347B1 (de)
JP (1) JP3062001B2 (de)
CN (1) CN1062735C (de)
AT (1) ATE207752T1 (de)
AU (1) AU680229B2 (de)
CA (1) CA2120538C (de)
DE (1) DE69428827T2 (de)
DK (1) DK0623347T3 (de)
ES (1) ES2166771T3 (de)
FR (1) FR2703590B1 (de)
HU (1) HU220764B1 (de)
IL (1) IL109212A (de)
NO (1) NO305304B1 (de)
NZ (1) NZ260244A (de)
PT (1) PT623347E (de)
ZA (1) ZA942358B (de)

Families Citing this family (39)

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Publication number Priority date Publication date Assignee Title
US6406714B1 (en) 1992-12-02 2002-06-18 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids
US5591730A (en) * 1993-10-12 1997-01-07 The Regents Of The University Of California Inhibition of urinary calculi growth
US20010007863A1 (en) 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
TW390813B (en) * 1994-04-29 2000-05-21 Merck & Co Inc Wet granulation formulation for bisphosphonic acids
US5462932A (en) * 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
WO1996039107A1 (en) * 1995-06-06 1996-12-12 Merck & Co., Inc. Bisphosphonate cement composition to prevent aseptic loosening of orthopedic implant devices
EP0753523A1 (de) * 1995-07-10 1997-01-15 Gador S.A. Amino-substuierte bisphosphonsäure
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
BR9712197A (pt) * 1996-10-04 1999-08-31 Merck & Co Inc Formulação farmacêutica líquida aquosa e processos de preparação da mesma, e, de inibição de reabsorção de osso.
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US5994329A (en) 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
US6432932B1 (en) 1997-07-22 2002-08-13 Merck & Co., Inc. Method for inhibiting bone resorption
US6015801A (en) * 1997-07-22 2000-01-18 Merck & Co., Inc. Method for inhibiting bone resorption
US6750340B2 (en) 1998-04-02 2004-06-15 Mbc Research, Inc. Bisphosphonate conjugates and methods of making and using the same
US8586781B2 (en) 1998-04-02 2013-11-19 Mbc Pharma, Inc. Bone targeted therapeutics and methods of making and using the same
US6896871B2 (en) 1998-04-02 2005-05-24 Mbc Research, Inc. Biphosphonate conjugates and methods of making and using the same
US7598246B2 (en) * 1998-04-02 2009-10-06 Mbc Pharma, Inc. Bisphosphonate conjugates and methods of making and using the same
GB2336311A (en) * 1998-04-15 1999-10-20 Merck & Co Inc Bisphosphonate Dosing Regimen
FR2784031B1 (fr) * 1998-10-02 2002-02-01 Sanofi Elf Utilisation de derives de l'acide bisphosphonique pour la preparation d'un medicament destine au traitement des boiteries
FR2803520B1 (fr) * 2000-01-12 2002-09-20 Ceva Sante Animale Procede pour augmenter la production d'oeufs et consolider la coquille des oeufs chez les volailles
EP1136069A1 (de) * 2000-03-21 2001-09-26 SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. Pharmazeutische Zusammensetzungen enthaltend Clodronate mit hoher lokaler Verträglichkeit bei intramuskulärer Verabreichung
CA2347330C (en) * 2001-05-10 2002-03-12 Pharmaceutical Partners Of Canada Inc. Liquid injectable formulation of disodium pamidronate
SK2532004A3 (en) * 2001-12-21 2004-11-03 Procter & Gamble Method for the treatment of bone disorders
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
AU2003226148A1 (en) * 2002-04-05 2003-10-27 Merck & Co., Inc. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
CA2481142C (en) * 2002-05-10 2012-11-13 F.Hoffmann-La Roche Ag Bisphosphonic acids for the treatment and prevention of osteoporosis
US20040137058A1 (en) * 2002-07-09 2004-07-15 Katdare Ashok V. Effervescent bisphosphonate formulation
US20040138180A1 (en) * 2002-10-03 2004-07-15 Barr Laboratories, Inc. Bisphosphonate composition and process for the preparation thereof
EP1790347B1 (de) * 2002-12-20 2014-12-24 F. Hoffmann-La Roche AG Tablette mit hohem gehalt an ibandronat
ITMI20040218A1 (it) * 2004-02-10 2004-05-10 Abiogen Pharma Spa Uso di neridronato sodico per promuovere la neoformazione ossea
US20050261250A1 (en) * 2004-05-19 2005-11-24 Merck & Co., Inc., Compositions and methods for inhibiting bone resorption
KR100564628B1 (ko) * 2004-06-16 2006-03-28 삼성전자주식회사 스플릿 게이트형 플래쉬 메모리 소자 및 그 제조방법
EP1781258A1 (de) * 2004-08-20 2007-05-09 Mepha AG Formulierungen von biphosphonaten
US8071574B2 (en) * 2005-02-22 2011-12-06 John Dennis Bobyn Implant improving local bone formation
US20070087052A1 (en) * 2005-10-19 2007-04-19 Katdare Ashok V Effervescent bisphosphonate formulation
EP1923049A1 (de) * 2006-11-17 2008-05-21 Besins Healthcare Pharmazeutische Zusammensetzungen mit einer Bisphosphonatverbindung
FR2954320B1 (fr) 2009-12-17 2012-06-15 Cll Pharma Composition pharmaceutique orale suprabiodisponible contenant un acide biphosphonique ou un de ses sels
US8882740B2 (en) * 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone
CA2843885C (en) 2011-08-01 2020-03-10 Mbc Pharma, Inc. Vitamin b6 derivatives of nucleotides, acyclonucleotides and acyclonucleoside phosphonates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194748B (it) * 1981-02-12 1988-09-28 Gentili Ist Spa Composizioni farmaceutiche per il trattamento di osteopatie
FR2531088B1 (fr) * 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
GB8419489D0 (en) * 1984-07-31 1984-09-05 Leo Pharm Prod Ltd Chemical compounds
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
GB8530603D0 (en) * 1985-12-12 1986-01-22 Leo Pharm Prod Ltd Chemical compounds
CA1339805C (en) * 1988-01-20 1998-04-07 Yasuo Isomura (cycloalkylamino)methylenebis(phosphonic acid) and medicines containing the same as an active
FR2629716B1 (fr) * 1988-04-07 1991-07-19 Sanofi Sa Composition pharmaceutique pour administration orale a base d'un derive d'acide diphosphonique
US4922007A (en) * 1989-06-09 1990-05-01 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
HUT68010A (en) 1991-12-17 1995-05-29 Procter & Gamble Pharma The use of bisphonates and parathyroid hormone for the treatment of osteoporosis
US5270365A (en) * 1991-12-17 1993-12-14 Merck & Co., Inc. Prevention and treatment of periodontal disease with alendronate
EP0600834A1 (de) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Verwendung von Methanbiphosphonsäurederivaten zur Herstellung eines Arzneimittels zur Behandlung von Knochenbrüchen
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery

Also Published As

Publication number Publication date
AU680229B2 (en) 1997-07-24
NO941185L (no) 1994-10-06
CN1062735C (zh) 2001-03-07
ES2166771T3 (es) 2002-05-01
HUT68310A (en) 1995-06-28
HU220764B1 (hu) 2002-05-28
PT623347E (pt) 2002-03-28
EP0623347A1 (de) 1994-11-09
JP3062001B2 (ja) 2000-07-10
DE69428827D1 (de) 2001-12-06
IL109212A0 (en) 1994-07-31
IL109212A (en) 2001-07-24
ZA942358B (en) 1995-10-05
AU5910294A (en) 1994-10-06
US5488041A (en) 1996-01-30
FR2703590B1 (fr) 1995-06-30
JPH0748261A (ja) 1995-02-21
NZ260244A (en) 1997-06-24
CA2120538C (en) 1999-02-23
CN1104091A (zh) 1995-06-28
CA2120538A1 (en) 1994-10-06
EP0623347B1 (de) 2001-10-31
FR2703590A1 (fr) 1994-10-14
NO941185D0 (no) 1994-03-30
DE69428827T2 (de) 2002-07-18
DK0623347T3 (da) 2002-02-11
NO305304B1 (no) 1999-05-10
HU9400967D0 (en) 1994-06-28

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