DK0620729T3 - Osmotisk indretning med forsinket aktivering af medikament-afgivningen - Google Patents

Osmotisk indretning med forsinket aktivering af medikament-afgivningen

Info

Publication number
DK0620729T3
DK0620729T3 DK93902985.6T DK93902985T DK0620729T3 DK 0620729 T3 DK0620729 T3 DK 0620729T3 DK 93902985 T DK93902985 T DK 93902985T DK 0620729 T3 DK0620729 T3 DK 0620729T3
Authority
DK
Denmark
Prior art keywords
drug delivery
osmotic device
delayed activation
delivery
time
Prior art date
Application number
DK93902985.6T
Other languages
Danish (da)
English (en)
Inventor
Patrick S-L Wong
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DK0620729T3 publication Critical patent/DK0620729T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DK93902985.6T 1992-01-10 1993-01-08 Osmotisk indretning med forsinket aktivering af medikament-afgivningen DK0620729T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/819,417 US5223265A (en) 1992-01-10 1992-01-10 Osmotic device with delayed activation of drug delivery

Publications (1)

Publication Number Publication Date
DK0620729T3 true DK0620729T3 (da) 1995-12-04

Family

ID=25228098

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93902985.6T DK0620729T3 (da) 1992-01-10 1993-01-08 Osmotisk indretning med forsinket aktivering af medikament-afgivningen

Country Status (16)

Country Link
US (2) US5223265A (es)
EP (1) EP0620729B1 (es)
JP (1) JP3514756B2 (es)
KR (1) KR100246157B1 (es)
AT (1) ATE127338T1 (es)
AU (1) AU659285B2 (es)
CA (1) CA2124829C (es)
DE (1) DE69300451T2 (es)
DK (1) DK0620729T3 (es)
ES (1) ES2076837T3 (es)
FI (1) FI943280A0 (es)
MX (1) MX9300101A (es)
NO (1) NO942525D0 (es)
NZ (1) NZ246796A (es)
WO (1) WO1993013759A1 (es)
ZA (1) ZA93133B (es)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
JPH08507700A (ja) * 1992-12-28 1996-08-20 ボシュ アンド ロム インコーポレイテッド 水性媒体内に活性物質を制御放出する組成物
US5290240A (en) * 1993-02-03 1994-03-01 Pharmetrix Corporation Electrochemical controlled dispensing assembly and method for selective and controlled delivery of a dispensing fluid
US5540665A (en) * 1994-01-31 1996-07-30 Alza Corporation Gas driven dispensing device and gas generating engine therefor
US5651979A (en) * 1995-03-30 1997-07-29 Gel Sciences, Inc. Apparatus and method for delivering a biologically active compound into a biological environment
US5817335A (en) * 1995-05-26 1998-10-06 Alza Corporation Osmotic device with high drug loading and delayed activation of drug delivery
DE69622857T2 (de) * 1995-06-02 2003-06-18 Alza Corp., Mountain View Osmotische vorrichtung mit verzögerten aktivieren der wirkstofffreisetzung und vollständige arzneistofffreisetzung
US5800422A (en) * 1995-06-02 1998-09-01 Alza Corporation Osmotic device with delayed activation of drug delivery and complete drug release
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
KR0124764Y1 (ko) * 1995-09-23 1998-09-15 양주환 의약 및 식품용 하드 공 캅셀
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US6486177B2 (en) * 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US5902605A (en) * 1996-04-18 1999-05-11 Alza Corporation Drug delivery device with minimal residual drug retention
AU3590497A (en) * 1996-07-15 1998-02-09 Alza Corporation Interlocking osmotic device
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
US6977074B2 (en) * 1997-07-10 2005-12-20 Mannkind Corporation Method of inducing a CTL response
US6994851B1 (en) 1997-07-10 2006-02-07 Mannkind Corporation Method of inducing a CTL response
MY125849A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
AU1828599A (en) * 1997-12-29 1999-07-19 Alza Corporation Osmotic delivery system with membrane plug retention mechanism
PT1041974E (pt) * 1997-12-30 2007-01-31 Alza Corp Sistema de entrega de agente benéfico como obturador de membrana
ATE248002T1 (de) 1997-12-31 2003-09-15 Alza Corp System zur überwachung einer osmotischen wirkstoffabgabevorrichtung
DE19835346A1 (de) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
US6551613B1 (en) * 1998-09-08 2003-04-22 Alza Corporation Dosage form comprising therapeutic formulation
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
WO2000059481A1 (en) 1999-04-06 2000-10-12 Pharmaquest Ltd. PHARMACEUTICAL DOSAGE FORM FOR PULSATILE DELIVERY OF d-threo-METHYLPHENIDATE AND A SECOND CNS STIMULANT
CA2402637C (en) 1999-12-21 2007-04-10 Alza Corporation Valve for osmotic devices
US6669954B2 (en) 2000-01-25 2003-12-30 John R. Crison Controlled release of drugs
AU2002219793A1 (en) * 2000-11-29 2002-06-11 Durect Corporation Devices and methods for controlled delivery from a drug delivery device
US6491684B1 (en) * 2001-05-22 2002-12-10 Durect Corporation Fluid delivery device having a water generating electrochemical/chemical pump and associated method
AU2002357935A1 (en) * 2001-12-18 2003-06-30 Alza Corporation Dosage form for providing time-varying patterns of drug delivery
JP2005533084A (ja) * 2002-06-28 2005-11-04 アルザ・コーポレーシヨン 液体の有効成分の製剤を含んでなりかつ膨張可能な浸透圧組成物によりその放出を制御する経口の投薬形態
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US7485322B2 (en) * 2002-12-24 2009-02-03 Lek Pharmaceuticals D.D. Modified release pharmaceutical composition
JP2007501661A (ja) * 2003-08-07 2007-02-01 アルヴィオラス，インコーポレイテッド 治療用医学器具、送達装置及び使用方法
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
CA2571554A1 (en) * 2004-06-28 2006-01-19 Alza Corporation A drug/polymer complex, preferably ciprofloxacin/hpmc, its method of manufacturing using lyophilization and its use in an osmotic device
CA2577583A1 (en) * 2004-08-19 2006-03-02 Alza Corporation Controlled release nanoparticle active agent formulation dosage forms and methods
US7350479B2 (en) * 2004-09-10 2008-04-01 United States Of America As Represented By The Secretary Of The Army System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp
AU2005313887B2 (en) * 2004-12-09 2011-10-27 Celgene Corporation Treatment using D-threo methylphenidate
AU2005321940B2 (en) * 2004-12-29 2012-04-19 Mannkind Corporation Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
DE102005001332A1 (de) * 2005-01-11 2006-07-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zweiteilige Kapsel mit Vorverschluss zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
WO2007011972A2 (en) * 2005-07-19 2007-01-25 Inverseon, Inc. Improved pharmacokinetic profile of beta-adrenergic inverse agonists for the treatment of pulmonary airway diseases
EP1959966B1 (en) 2005-11-28 2020-06-03 Marinus Pharmaceuticals, Inc. Ganaxolone formulations and methods for the making and use thereof
US7762426B2 (en) * 2006-03-16 2010-07-27 The Procter & Gamble Company Seal for dispensing container having dispensing opening
CA2651855C (en) 2006-05-30 2011-08-02 Intarcia Therapeutics, Inc. Two-piece, internal-channel osmotic delivery system flow modulator
ES2422864T3 (es) 2006-08-09 2013-09-16 Intarcia Therapeutics, Inc Sistemas de liberación osmótica y unidades de pistón
JP2010510988A (ja) 2006-11-28 2010-04-08 マリナス ファーマシューティカルズ ナノ粒子製剤とその製造方法およびその利用
PT2157967E (pt) 2007-04-23 2013-04-03 Intarcia Therapeutics Inc Formulações de suspensões de péptidos insulinotrópicos e suas utilizações
CN101827571A (zh) * 2007-10-15 2010-09-08 葛兰素集团有限公司 用于释放一种或多种药物成分的多部分剂型的连接件及所得剂型
EP2209455A1 (en) * 2007-10-15 2010-07-28 Glaxo Group Limited Paneled capsule shells for release of pharmaceutical compositions
WO2009050193A1 (en) * 2007-10-15 2009-04-23 Glaxo Group Limited Method and apparatus for manufacturing filled linkers
EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
KR101823699B1 (ko) 2009-09-28 2018-01-30 인타르시아 세라퓨틱스 인코포레이티드 실질 항정상태 약물 전달의 신속 확립 및/또는 종결
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
RU2622749C9 (ru) * 2011-10-06 2017-08-30 Байо Кэпсьюл Фармасьютикал Энд Ньютришнал Продактс Проприетери Лимитед Способ и устройство для изготовления капсулы
US9456987B2 (en) 2013-04-03 2016-10-04 Binutra, Inc. Capsule with internal diaphragm
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US10925639B2 (en) 2015-06-03 2021-02-23 Intarcia Therapeutics, Inc. Implant placement and removal systems
US11160759B1 (en) 2015-10-09 2021-11-02 Combocap, Inc. Capsule with internal diaphragm for improved bioavailability
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
KR102518846B1 (ko) 2016-08-11 2023-04-05 오비드 테라퓨틱스 인크. 간질 장애의 치료를 위한 방법 및 조성물
KR20190104039A (ko) 2017-01-03 2019-09-05 인타르시아 세라퓨틱스 인코포레이티드 Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
US11266662B2 (en) 2018-12-07 2022-03-08 Marinus Pharmaceuticals, Inc. Ganaxolone for use in prophylaxis and treatment of postpartum depression
MX2022001553A (es) 2019-08-05 2022-04-18 Marinus Pharmaceuticals Inc Ganaxolona para su uso en el tratamiento del estado epileptico.
KR20220134529A (ko) 2019-12-06 2022-10-05 마리누스 파마슈티컬스 인코포레이티드 복합 결절성 경화증의 치료에 사용하기 위한 가낙솔론
WO2024075723A1 (ja) * 2022-10-07 2024-04-11 テルモ株式会社 薬剤投与装置
WO2024202782A1 (ja) * 2023-03-30 2024-10-03 テルモ株式会社 投与装置、及び被投与物の投与状態の判断方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3995631A (en) * 1971-01-13 1976-12-07 Alza Corporation Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient
US4034756A (en) * 1971-01-13 1977-07-12 Alza Corporation Osmotically driven fluid dispenser
US3865108A (en) * 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US4002173A (en) * 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
GB1478759A (en) * 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US4063064A (en) * 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
US4111202A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4207893A (en) * 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4265874A (en) * 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4320759A (en) * 1980-04-28 1982-03-23 Alza Corporation Dispenser with diffuser
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4612008A (en) * 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4777049A (en) * 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
US4601896A (en) * 1984-03-21 1986-07-22 Mark Nugent Pharmaceutical capsule compositions and structures for gastric sensitive materials
US4955881A (en) * 1985-08-16 1990-09-11 Alza Corporation Ruminant dispensing device
US4643731A (en) * 1985-08-16 1987-02-17 Alza Corporation Means for providing instant agent from agent dispensing system
US4874388A (en) * 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5023088A (en) * 1987-06-25 1991-06-11 Alza Corporation Multi-unit delivery system
US4872873A (en) * 1987-12-14 1989-10-10 Merck & Co., Inc. Controlled release bolus device
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US4976966A (en) * 1988-12-29 1990-12-11 Alza Corporation Delayed release osmotically driven fluid dispenser
GB8903564D0 (en) * 1989-02-16 1989-04-05 Rashid Abdul Drug dispensing device
US5178866A (en) * 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
US5017381A (en) * 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system
MX9200331A (es) * 1991-01-30 1992-10-01 Alza Corp Alza Corp Dispositivo osmotico para surtido retardado de agedispositivo osmotico para surtido retardado de agente. nte.

Also Published As

Publication number Publication date
ATE127338T1 (de) 1995-09-15
DE69300451T2 (de) 1996-05-02
ZA93133B (en) 1993-08-16
WO1993013759A1 (en) 1993-07-22
EP0620729A1 (en) 1994-10-26
JPH07504401A (ja) 1995-05-18
DE69300451D1 (de) 1995-10-12
US5312390A (en) 1994-05-17
KR940703654A (ko) 1994-12-12
AU3436893A (en) 1993-08-03
CA2124829A1 (en) 1993-07-22
MX9300101A (es) 1994-01-31
AU659285B2 (en) 1995-05-11
US5223265A (en) 1993-06-29
NZ246796A (en) 1995-10-26
EP0620729B1 (en) 1995-09-06
NO942525L (no) 1994-07-05
KR100246157B1 (ko) 2000-04-01
JP3514756B2 (ja) 2004-03-31
NO942525D0 (no) 1994-07-05
ES2076837T3 (es) 1995-11-01
CA2124829C (en) 2004-03-16
FI943280A (fi) 1994-07-08
FI943280A0 (fi) 1994-07-08

Similar Documents

Publication Publication Date Title
DK0620729T3 (da) Osmotisk indretning med forsinket aktivering af medikament-afgivningen
DK0523172T3 (da) Osmotisk doseringssystem til afgivelse af flydende lægemiddel
DK0569534T3 (da) Osmotisk indretning til forsinket udlevering af et middel
FI934653A (fi) Doseringsformer innehaollande polymerer med olik molekylvikt
PT96337A (pt) Dispositivo distribuidor de longa duracao incluindo uma dose de carregamento
ITRM920361A0 (it) Composizioni farmaceutiche contenenti un composto allilamminico quale principio attivo.
IT8467283A1 (it) Dispositivo osmotico avente duplice attivita' termodinamica per la erogazione a velocita' controllata di una sostanza, particolarmente un farmaco, all'ambiente a cui e' destinata.
FR2674747B1 (fr) Dispositif distributeur de gouttes de petit volume, notamment pour soins ophtalmologiques.
ATE444768T1 (de) Wirkstoffabgabesysteme
ATE208188T1 (de) Osmotische vorrichtung mit hohem gehalt an wirkstoffen und verzögertem aktivieren der wirkstofffreisetzung
ATE221769T1 (de) Osmotische vorrichtung mit verzögerten aktivieren der wirkstofffreisetzung und vollständige arzneistofffreisetzung
DK0469440T3 (da) Faste orale applikationsformer, der som aktivt stof indeholder ifosamid
CA2220301A1 (en) Osmotic device with delayed activation of drug delivery and complete drug release
NO20014406D0 (no) Doseringsaerosoler med isobutan som drivmiddel