DK0613685T3 - Liposomes containing chlorhexidine diacetate or chlorhexide indigluconate - Google Patents

Liposomes containing chlorhexidine diacetate or chlorhexide indigluconate

Info

Publication number
DK0613685T3
DK0613685T3 DK94102340T DK94102340T DK0613685T3 DK 0613685 T3 DK0613685 T3 DK 0613685T3 DK 94102340 T DK94102340 T DK 94102340T DK 94102340 T DK94102340 T DK 94102340T DK 0613685 T3 DK0613685 T3 DK 0613685T3
Authority
DK
Denmark
Prior art keywords
indigluconate
chlorhexide
liposomes containing
chlorhexidine diacetate
containing chlorhexidine
Prior art date
Application number
DK94102340T
Other languages
Danish (da)
Inventor
Moncho Jorge Olive
Garcia Jose Javier Echeverria
Ensenat Pedro Gonzalez
Guenther Maierhofer
Original Assignee
Moncho Jorge Olive
Garcia Jose Javier Echeverria
Ensenat Pedro Gonzalez
Guenther Maierhofer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moncho Jorge Olive, Garcia Jose Javier Echeverria, Ensenat Pedro Gonzalez, Guenther Maierhofer filed Critical Moncho Jorge Olive
Application granted granted Critical
Publication of DK0613685T3 publication Critical patent/DK0613685T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Liposomes which contain encapsulated chlorhexidine diacetate or chlorhexidine digluconate and whose composition comprises, besides bilayer-forming lipids, additionally surfactants are described. Advantages which may be mentioned for liposomal administration compared with the free form of chlorhexidine are higher and longer activity and fewer side effects.
DK94102340T 1993-03-02 1994-02-16 Liposomes containing chlorhexidine diacetate or chlorhexide indigluconate DK0613685T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4306475A DE4306475A1 (en) 1993-03-02 1993-03-02 Liposomes containing chlorhexidine diacetate or chlorhexidine digluconate

Publications (1)

Publication Number Publication Date
DK0613685T3 true DK0613685T3 (en) 1999-07-26

Family

ID=6481737

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94102340T DK0613685T3 (en) 1993-03-02 1994-02-16 Liposomes containing chlorhexidine diacetate or chlorhexide indigluconate

Country Status (5)

Country Link
EP (1) EP0613685B1 (en)
AT (1) ATE173158T1 (en)
DE (2) DE4306475A1 (en)
DK (1) DK0613685T3 (en)
ES (1) ES2124328T3 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863556A (en) * 1993-08-20 1999-01-26 Euro-Celtique, S.A. Preparations for the external application of antiseptic agents and/or agents promoting the healing of wounds
DE9312509U1 (en) * 1993-08-20 1993-10-28 Euro-Celtique S.A., Luxemburg/Luxembourg Preparations for external administration of antiseptic and / or wound healing promoting agents
US5902604A (en) * 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
DE19522693A1 (en) * 1995-06-22 1997-01-02 Dianorm G Maierhofer Gmbh Composition for the production of finely dispersed systems and process for their production
ES2118053B1 (en) * 1997-02-27 1999-03-01 Julia Capmany Font M Luisa PRODUCT FOR THE CLEANING OF SKIN AND SKINS.
DE19813686A1 (en) * 1998-03-27 1999-09-30 Roeko Gmbh & Co Agent for treatment or filling of a tooth root canal containing antibacterial and optionally carriers and fillers
RU2211693C2 (en) * 1998-05-27 2003-09-10 Юроселтик С.А. Preparations for injecting antiphlogistic, especially, antiseptic substances and/or those favoring wound healing into superior respiratory pathways and/or ear
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
ES2235891T3 (en) 1999-05-27 2005-07-16 Euro-Celtique S.A. USE OF ANTISEPTICS IN THE MANUFACTURE OF A PHARMACEUTICAL PREPARATION FOR THE PREVENTION AND TREATMENT OF INFECTIONS AND / OR FUNCTIONAL RESTRUCTURING OF THE FABRIC INSIDE THE HUMAN BODY.
US7297344B1 (en) 1999-05-27 2007-11-20 Euro-Celtique, S.A. Preparations for the promotion of wound healing in the upper respiratory tract and/or ear
EP1180017B8 (en) * 1999-05-27 2010-05-19 Euro-Celtique S.A. Preparations with povidon iodine for wound treatment
US6416745B1 (en) * 2001-05-03 2002-07-09 Block Drug Company, Inc. Dental composition for treating hypersensitive teeth
DE102006015271A1 (en) * 2006-04-01 2007-10-11 Lohmann & Rauscher Gmbh & Co. Kg Biguanide-containing liposomes
EP2361502A1 (en) * 2010-02-05 2011-08-31 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Active antimicrobial compositions, coatings and methods for controlling pathogenic bacteria
GB201200490D0 (en) 2012-01-12 2012-02-22 Univ Bath Wound dressing
FR3071729A1 (en) * 2017-10-04 2019-04-05 Cementic DISINFECTANT DENTAL CEMENTS COMPRISING LIPOSOMES

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0761940B2 (en) * 1986-11-17 1995-07-05 株式会社資生堂 Liposomal formulation for outer skin
WO1992003122A1 (en) * 1990-08-24 1992-03-05 Gregor Cevc Preparation for application of active substances in the form of minimum-sized droplets
DE4111982C2 (en) * 1991-04-12 1998-12-24 Merz & Co Gmbh & Co Stable small particulate liposome preparations, their preparation and use
FR2676362B3 (en) * 1991-05-17 1993-08-13 Oreal PROCESS FOR INCREASING THE ACTIVITY OF AT LEAST ONE ACTIVE IN A COMPOSITION FOR COSMETIC AND / OR DERMOPHARMACEUTICAL USE AND COMPOSITION FOR CARRYING OUT SAID METHOD.

Also Published As

Publication number Publication date
DE4306475A1 (en) 1994-09-08
ES2124328T3 (en) 1999-02-01
EP0613685A1 (en) 1994-09-07
EP0613685B1 (en) 1998-11-11
ATE173158T1 (en) 1998-11-15
DE59407247D1 (en) 1998-12-17

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