DK0606391T3 - Inhibering af karforsnævring under anvendelse af anti-PADGEM-antistoffer - Google Patents

Inhibering af karforsnævring under anvendelse af anti-PADGEM-antistoffer

Info

Publication number
DK0606391T3
DK0606391T3 DK92922039T DK92922039T DK0606391T3 DK 0606391 T3 DK0606391 T3 DK 0606391T3 DK 92922039 T DK92922039 T DK 92922039T DK 92922039 T DK92922039 T DK 92922039T DK 0606391 T3 DK0606391 T3 DK 0606391T3
Authority
DK
Denmark
Prior art keywords
padgem
inhibition
vascular
intravascular
vascular narrowing
Prior art date
Application number
DK92922039T
Other languages
Danish (da)
English (en)
Inventor
Theresa M Palabrica
Bruce E Furie
Barbara C Furie
Roy R Lobb
Christopher D Benjamin
Original Assignee
Biogen Inc
New England Medical Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc, New England Medical Center Inc filed Critical Biogen Inc
Application granted granted Critical
Publication of DK0606391T3 publication Critical patent/DK0606391T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK92922039T 1991-09-30 1992-09-30 Inhibering af karforsnævring under anvendelse af anti-PADGEM-antistoffer DK0606391T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76883491A 1991-09-30 1991-09-30
PCT/US1992/008163 WO1993006863A1 (fr) 1991-09-30 1992-09-30 Inhibition du retrecissement vasculaire par l'utilisation d'anticorps anti-padgem

Publications (1)

Publication Number Publication Date
DK0606391T3 true DK0606391T3 (da) 1999-05-03

Family

ID=25083621

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92922039T DK0606391T3 (da) 1991-09-30 1992-09-30 Inhibering af karforsnævring under anvendelse af anti-PADGEM-antistoffer

Country Status (9)

Country Link
EP (1) EP0606391B1 (fr)
JP (1) JPH07502726A (fr)
AT (1) ATE169227T1 (fr)
AU (1) AU678757B2 (fr)
CA (1) CA2120240A1 (fr)
DE (1) DE69226531T2 (fr)
DK (1) DK0606391T3 (fr)
ES (1) ES2123010T3 (fr)
WO (1) WO1993006863A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770198A (en) * 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
NZ527820A (en) * 1993-11-05 2005-04-29 Centocor Inc Platelet-specific chimeric immunoglobulin and methods of use therefor
AU2305201A (en) * 1993-11-05 2001-05-03 Centocor Inc. Platelet-specific chimeric immunoglobulin and methods of use therefor
EP1714661A3 (fr) * 2000-05-19 2012-03-14 The Center for Blood Research, INC. Procedes pour diagnostiquer et traiter des troubles hemostatiques par modulation de l'activité de la p-selectine
DE60118362T2 (de) 2000-05-19 2007-05-24 The Center for Blood Research, Inc., Boston VERFAHREN ZUR BEHANDLUNG VON HÄMOSTATISCHEN STÖRUNGEN DURCH LöSLICHES P-SELECTIN
ES2403055T3 (es) 2004-04-13 2013-05-13 F. Hoffmann-La Roche Ag Anticuerpos anti-P-selectina
US20110212096A1 (en) 2006-12-01 2011-09-01 Scott Rollins Anti-p-selectin antibodies and methods of their use and identification
US8945565B2 (en) 2006-12-01 2015-02-03 Selexys Pharmaceuticals Corporation Methods of treating inflammatory or thrombotic conditions with anti-P-selectin antibodies
ES2699273T3 (es) 2006-12-01 2019-02-08 Novartis Ag Anticuerpos anti-P-selectina y métodos de uso de los mismos para tratar enfermedades inflamatorias
PE20110302A1 (es) 2008-09-19 2011-05-21 Hoffmann La Roche Formulacion farmaceutica de un anticuerpo contra p-selectina
US20200087403A1 (en) 2017-03-15 2020-03-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Pharmaceutical compositions for the treatment of thrombosis in patients suffering from a myeloproliferative neoplasm
US20200200774A1 (en) 2017-06-20 2020-06-25 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for identifying whether patients with acute decompensated heart failure (adhf) exhibit a hypercoagulable state

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991001380A1 (fr) * 1989-07-25 1991-02-07 Institut National De La Sante Et De La Recherche Medicale Anticorps monoclonaux diriges contre des proteines impliquees dans les fonctions plaquettaires, leur application en tant qu'agent diagnostique et therapeutique
ES2097765T3 (es) * 1989-10-20 1997-04-16 New England Medical Center Inc Un sistema de inhibicion del enlazado de celulas intermediado por padgem.
WO1991007993A1 (fr) * 1989-11-30 1991-06-13 Mathew Vadas Facteurs anti-inflammatoires et anti-adhesifs

Also Published As

Publication number Publication date
ES2123010T3 (es) 1999-01-01
DE69226531D1 (de) 1998-09-10
AU678757B2 (en) 1997-06-12
WO1993006863A1 (fr) 1993-04-15
CA2120240A1 (fr) 1993-03-31
ATE169227T1 (de) 1998-08-15
DE69226531T2 (de) 1999-05-06
JPH07502726A (ja) 1995-03-23
EP0606391A1 (fr) 1994-07-20
AU2869492A (en) 1993-05-03
EP0606391B1 (fr) 1998-08-05

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