DK0564461T3 - Anvendelse af antistoffer mod TNF eller fragmenter afledt deraf og xanthinderivater til kombinationsterapi samt præparater dertil - Google Patents

Anvendelse af antistoffer mod TNF eller fragmenter afledt deraf og xanthinderivater til kombinationsterapi samt præparater dertil

Info

Publication number
DK0564461T3
DK0564461T3 DK91918565.2T DK91918565T DK0564461T3 DK 0564461 T3 DK0564461 T3 DK 0564461T3 DK 91918565 T DK91918565 T DK 91918565T DK 0564461 T3 DK0564461 T3 DK 0564461T3
Authority
DK
Denmark
Prior art keywords
tnf
xanthine
antibody
range
xanthine derivative
Prior art date
Application number
DK91918565.2T
Other languages
English (en)
Inventor
Mark William Bodmer
Hiristo Anagnostopulos
Ulrich Gebert
Heinz Hanel
Michael Limbert
Gerald Anthony Higgs
Original Assignee
Hoechst Ag
Celltech Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Celltech Therapeutics Ltd filed Critical Hoechst Ag
Application granted granted Critical
Publication of DK0564461T3 publication Critical patent/DK0564461T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK91918565.2T 1990-11-01 1991-10-30 Anvendelse af antistoffer mod TNF eller fragmenter afledt deraf og xanthinderivater til kombinationsterapi samt præparater dertil DK0564461T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909023783A GB9023783D0 (en) 1990-11-01 1990-11-01 Pharmaceutical product

Publications (1)

Publication Number Publication Date
DK0564461T3 true DK0564461T3 (da) 1997-01-20

Family

ID=10684716

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91918565.2T DK0564461T3 (da) 1990-11-01 1991-10-30 Anvendelse af antistoffer mod TNF eller fragmenter afledt deraf og xanthinderivater til kombinationsterapi samt præparater dertil

Country Status (15)

Country Link
EP (1) EP0564461B1 (da)
JP (1) JP3468515B2 (da)
KR (1) KR930701970A (da)
AT (1) ATE146971T1 (da)
AU (1) AU653180B2 (da)
CA (1) CA2094154A1 (da)
DE (1) DE69123984T2 (da)
DK (1) DK0564461T3 (da)
ES (1) ES2096662T3 (da)
GB (1) GB9023783D0 (da)
GR (1) GR3022210T3 (da)
HU (1) HUT70267A (da)
NO (1) NO931580D0 (da)
WO (1) WO1992007585A1 (da)
ZA (1) ZA918712B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9109645D0 (en) * 1991-05-03 1991-06-26 Celltech Ltd Recombinant antibodies
WO1994008619A1 (en) * 1992-10-08 1994-04-28 The Kennedy Institute Of Rheumatology Treatment of autoimmune and inflammatory disorders
US6270766B1 (en) 1992-10-08 2001-08-07 The Kennedy Institute Of Rheumatology Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
US6770279B1 (en) 1992-10-08 2004-08-03 The Kennedy Institute Of Rheumatology TNFα antagonists and cyclosporin in therapy of rheumatoid arthritis
DK0701571T3 (da) * 1993-06-03 1997-09-15 Therapeutic Antibodies Inc Antistoffragmenter til terapi
WO1995013075A1 (en) * 1993-11-12 1995-05-18 Cell Therapeutics, Inc. Method for preventing tissue injury from hypoxia
DE4411660A1 (de) * 1994-04-05 1995-10-12 Hoechst Ag Verwendung von Xanthinderivaten zur Reduktion der pathologischen Hyperreagibilität eosinophiler Granulozyten, neue Xanthinverbindungen und Verfahren zu deren Herstellung
JP2001513754A (ja) * 1996-12-06 2001-09-04 アムジェン インコーポレイテッド Tnf媒介疾患を処置するためのtnf結合タンパク質を使用する組み合わせ治療
EP1352656A3 (en) * 1996-12-06 2004-02-04 Amgen Inc. Combination therapy using a TNF binding protein for treating TNF-mediated diseases
US6294350B1 (en) * 1997-06-05 2001-09-25 Dalhousie University Methods for treating fibroproliferative diseases
US6395273B1 (en) * 1998-06-10 2002-05-28 Promega Corporation Prevention and treatment of inflammatory bowel disease

Also Published As

Publication number Publication date
HU9301093D0 (en) 1993-07-28
AU653180B2 (en) 1994-09-22
ATE146971T1 (de) 1997-01-15
NO931580D0 (no) 1993-04-30
ES2096662T3 (es) 1997-03-16
DE69123984D1 (de) 1997-02-13
EP0564461A1 (en) 1993-10-13
EP0564461B1 (en) 1997-01-02
KR930701970A (ko) 1993-09-08
DE69123984T2 (de) 1997-05-22
AU8758391A (en) 1992-05-26
JPH06502629A (ja) 1994-03-24
HUT70267A (en) 1995-09-28
CA2094154A1 (en) 1992-05-02
JP3468515B2 (ja) 2003-11-17
ZA918712B (en) 1992-09-30
GB9023783D0 (en) 1990-12-12
GR3022210T3 (en) 1997-04-30
WO1992007585A1 (en) 1992-05-14

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