DK0557301T3 - 5-Fluor-2,4,6-pyrimidintriamin-forbindelser til hindring af håraffald - Google Patents
5-Fluor-2,4,6-pyrimidintriamin-forbindelser til hindring af håraffaldInfo
- Publication number
- DK0557301T3 DK0557301T3 DK91917952.3T DK91917952T DK0557301T3 DK 0557301 T3 DK0557301 T3 DK 0557301T3 DK 91917952 T DK91917952 T DK 91917952T DK 0557301 T3 DK0557301 T3 DK 0557301T3
- Authority
- DK
- Denmark
- Prior art keywords
- fluoro
- hair loss
- minoxidil
- prevent hair
- triamine compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61269590A | 1990-11-14 | 1990-11-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0557301T3 true DK0557301T3 (da) | 1995-07-24 |
Family
ID=24454264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK91917952.3T DK0557301T3 (da) | 1990-11-14 | 1991-09-20 | 5-Fluor-2,4,6-pyrimidintriamin-forbindelser til hindring af håraffald |
Country Status (10)
Country | Link |
---|---|
US (1) | US5373012A (da) |
EP (1) | EP0557301B1 (da) |
JP (1) | JPH06501947A (da) |
AT (1) | ATE120190T1 (da) |
AU (1) | AU651630B2 (da) |
CA (1) | CA2092811A1 (da) |
DE (1) | DE69108402T2 (da) |
DK (1) | DK0557301T3 (da) |
ES (1) | ES2070513T3 (da) |
WO (1) | WO1992008705A1 (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7914814B2 (en) | 1997-09-17 | 2011-03-29 | Strategic Science & Technologies, Llc | Topical delivery of arginine of cause beneficial effects |
US7629384B2 (en) | 1997-09-17 | 2009-12-08 | Strategic Science & Technologies, Llc | Topical delivery of L-arginine to cause beneficial effects |
US9226909B2 (en) | 2004-04-19 | 2016-01-05 | Strategic Science & Technologies, Llc | Beneficial effects of increasing local blood flow |
WO2005102307A2 (en) | 2004-04-19 | 2005-11-03 | Strategic Science & Technologies, Llc | Beneficial effects of increasing local blood flow |
BRPI0925099A2 (pt) | 2009-06-24 | 2018-10-16 | Strategic Science & Tech Llc | composição tópica contendo ibuprofeno |
EP2445493A1 (en) | 2009-06-24 | 2012-05-02 | Strategic Science & Technologies, LLC | Topical composition containing naproxen |
US11684624B2 (en) | 2009-06-24 | 2023-06-27 | Strategic Science & Technologies, Llc | Treatment of erectile dysfunction and other indications |
CN103429247A (zh) | 2010-12-29 | 2013-12-04 | 战略科学与技术有限责任公司 | 勃起功能障碍和其它适应症的治疗 |
WO2012092523A1 (en) | 2010-12-29 | 2012-07-05 | Strategic Science & Technologies, Llc | Systems and methods for treatment of allergies and other indications |
CZ305457B6 (cs) | 2011-02-28 | 2015-09-30 | Ústav organické chemie a biochemie, Akademie věd ČR v. v. i. | Pyrimidinové sloučeniny inhibující tvorbu oxidu dusnatého a prostaglandinu E2, způsob výroby a použití |
HU230149B1 (hu) * | 2012-11-21 | 2015-09-28 | Richter Gedeon Nyrt. | Új eljárás triklór-pirimidin-amin származékok előállítására |
CA3209849A1 (en) * | 2014-10-29 | 2016-05-06 | Samson Clinical Pty Ltd | Use of oral minoxidil to treat alopecia areata |
CN109485608B (zh) * | 2018-12-24 | 2020-09-22 | 大连大学 | 一种4,6-二氯-5-氟-2-氨基嘧啶工业化生产方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3461461A (en) * | 1965-11-01 | 1969-08-12 | Upjohn Co | 6-amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidines |
US3464987A (en) * | 1966-02-21 | 1969-09-02 | Upjohn Co | 1,2-dihydro-1-hydroxy-2-imino-6-(lower alkyl)pyrimidines |
US3644364A (en) * | 1970-03-31 | 1972-02-22 | Upjohn Co | Compounds and process |
US4139619A (en) * | 1976-05-24 | 1979-02-13 | The Upjohn Company | 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth |
US4596812A (en) * | 1976-05-24 | 1986-06-24 | The Upjohn Company | Methods and solutions for treating male pattern alopecia |
US4287338A (en) * | 1980-03-10 | 1981-09-01 | The Upjohn Company | Sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts |
LU86695A1 (fr) * | 1986-12-01 | 1988-07-14 | Oreal | Nouveaux derives de piperazinyl-1 pyrimidine,leur preparation et leur application en therapeutique et cosmetique |
DE59108699D1 (de) * | 1990-08-10 | 1997-06-12 | Ciba Geigy Ag | Naphthylalkylaminopyrimidin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Schädlingsbekämpfungsmittel |
-
1991
- 1991-09-20 EP EP91917952A patent/EP0557301B1/en not_active Expired - Lifetime
- 1991-09-20 JP JP3516732A patent/JPH06501947A/ja active Pending
- 1991-09-20 CA CA002092811A patent/CA2092811A1/en not_active Abandoned
- 1991-09-20 DE DE69108402T patent/DE69108402T2/de not_active Expired - Fee Related
- 1991-09-20 ES ES91917952T patent/ES2070513T3/es not_active Expired - Lifetime
- 1991-09-20 AT AT91917952T patent/ATE120190T1/de active
- 1991-09-20 WO PCT/US1991/006728 patent/WO1992008705A1/en active IP Right Grant
- 1991-09-20 DK DK91917952.3T patent/DK0557301T3/da active
- 1991-09-20 AU AU87206/91A patent/AU651630B2/en not_active Ceased
-
1993
- 1993-05-10 US US08/059,552 patent/US5373012A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5373012A (en) | 1994-12-13 |
EP0557301B1 (en) | 1995-03-22 |
ATE120190T1 (de) | 1995-04-15 |
DE69108402D1 (de) | 1995-04-27 |
CA2092811A1 (en) | 1992-05-15 |
ES2070513T3 (es) | 1995-06-01 |
AU651630B2 (en) | 1994-07-28 |
AU8720691A (en) | 1992-06-11 |
DE69108402T2 (de) | 1995-10-05 |
EP0557301A1 (en) | 1993-09-01 |
WO1992008705A1 (en) | 1992-05-29 |
JPH06501947A (ja) | 1994-03-03 |
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