DK0548024T3 - Aminosulfonsyrederivater samt fremgangsmåder til deres fremstilling - Google Patents

Aminosulfonsyrederivater samt fremgangsmåder til deres fremstilling

Info

Publication number
DK0548024T3
DK0548024T3 DK92810989.1T DK92810989T DK0548024T3 DK 0548024 T3 DK0548024 T3 DK 0548024T3 DK 92810989 T DK92810989 T DK 92810989T DK 0548024 T3 DK0548024 T3 DK 0548024T3
Authority
DK
Denmark
Prior art keywords
acid derivatives
gla
preparation
methods
well
Prior art date
Application number
DK92810989.1T
Other languages
Danish (da)
English (en)
Inventor
Gerhard Dr Baschang
Albert Dr Hartmann
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of DK0548024T3 publication Critical patent/DK0548024T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK92810989.1T 1991-12-19 1992-12-11 Aminosulfonsyrederivater samt fremgangsmåder til deres fremstilling DK0548024T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH377691 1991-12-19

Publications (1)

Publication Number Publication Date
DK0548024T3 true DK0548024T3 (da) 1997-01-27

Family

ID=4263244

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92810989.1T DK0548024T3 (da) 1991-12-19 1992-12-11 Aminosulfonsyrederivater samt fremgangsmåder til deres fremstilling

Country Status (15)

Country Link
US (1) US5342977A (fr)
EP (1) EP0548024B1 (fr)
JP (1) JP3383335B2 (fr)
AT (1) ATE147404T1 (fr)
AU (1) AU661355B2 (fr)
CA (1) CA2085715A1 (fr)
DE (1) DE59207848D1 (fr)
DK (1) DK0548024T3 (fr)
ES (1) ES2096064T3 (fr)
GR (1) GR3022244T3 (fr)
IL (1) IL104121A (fr)
MX (1) MX9207455A (fr)
NZ (1) NZ245507A (fr)
SG (1) SG47406A1 (fr)
ZA (1) ZA929831B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU666789B2 (en) * 1992-12-28 1996-02-22 Takeda Chemical Industries Ltd. 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
US20040208875A1 (en) * 1995-03-15 2004-10-21 Queen's University At Kingston Method for treating amyloidosis
EP0641776A3 (fr) * 1993-09-08 1997-05-02 Takeda Chemical Industries Ltd Dérivés de thioglycérol.
WO1999035162A1 (fr) * 1998-01-07 1999-07-15 Jenner Biotherapies, Inc. Immunomodulateurs therapeutiques encapsules dans des liposomes
US20020022657A1 (en) * 1998-02-11 2002-02-21 Francine Gervais Methods for modulating neuronal cell death
WO2000064420A2 (fr) * 1999-04-28 2000-11-02 Queen's University At Kingston Compositions et procedes pour traiter l'amylose
GB9915074D0 (en) * 1999-06-28 1999-08-25 Cortecs Plc Ligand-binding composition
US7082569B2 (en) 2001-01-17 2006-07-25 Outlooksoft Corporation Systems and methods providing dynamic spreadsheet functionality
US7414076B2 (en) * 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) * 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
WO2006059252A2 (fr) * 2004-11-12 2006-06-08 Neurochem (International) Limited Procedes et compositions fluorees pour le traitement de maladies associees aux amyloides
JP2008520647A (ja) * 2004-11-16 2008-06-19 ニューロケム (インターナショナル) リミテッド Cnsおよびアミロイド関連疾患治療のための化合物
CA2900876A1 (fr) 2004-12-22 2006-08-17 Bhi Limited Partnership Methodes et compositions de traitement de maladies liees a l'amyloide
TW200716088A (en) * 2005-04-15 2007-05-01 Neurochem Int Ltd Formulations and methods for treating amyloidosis
AU2006342958A1 (en) * 2005-12-22 2007-11-08 Bellus Health (International) Limited Treatment of renal disorders, diabetic nephropathy and dyslipidemias
WO2009019534A2 (fr) 2006-10-12 2009-02-12 Bellus Health (International) Limited Procédés, composés, compositions et véhicules permettant de délivrer l'acide 3-amino-1-propane sulfonique
EP2120905A1 (fr) * 2006-12-22 2009-11-25 BELLUS Health (International) Limited Procédés, composés et compositions permettant de traiter des troubles métaboliques et le diabète
WO2011119759A1 (fr) * 2010-03-23 2011-09-29 Irm Llc Composés (lipopeptides à base de cystéine) et compositions en tant qu'agonistes des tlr2 utilisés pour traiter des infections, inflammations, maladies respiratoires entre autres
ES2785108T3 (es) * 2011-03-24 2020-10-05 Glaxosmithkline Biologicals Sa Nanoemulsiones adyuvantes con fosfolípidos
CN105152986B (zh) * 2015-09-09 2017-08-25 武汉华纳联合药业有限公司 半胱氨酸‑高牛磺酸二肽及其衍生物及其医药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2860893D1 (en) * 1977-06-20 1981-11-05 Ciba Geigy Ag Lipopeptides, process for their preparation and pharmaceutical compositions containing them
EP0014815A3 (fr) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Dérivés peptidiques, procédé pour leur préparation et intermédiaires, et compositions pharmaceutiques contenant un de ces composés
DE3485094D1 (de) * 1983-01-25 1991-10-31 Ciba Geigy Ag Neue peptidderivate.

Also Published As

Publication number Publication date
EP0548024B1 (fr) 1997-01-08
ATE147404T1 (de) 1997-01-15
IL104121A0 (en) 1993-05-13
NZ245507A (en) 1995-04-27
MX9207455A (es) 1993-12-01
GR3022244T3 (en) 1997-04-30
JPH05255239A (ja) 1993-10-05
IL104121A (en) 1998-01-04
AU3018392A (en) 1993-06-24
JP3383335B2 (ja) 2003-03-04
ES2096064T3 (es) 1997-03-01
DE59207848D1 (de) 1997-02-20
CA2085715A1 (fr) 1993-06-20
US5342977A (en) 1994-08-30
ZA929831B (en) 1993-06-21
EP0548024A2 (fr) 1993-06-23
AU661355B2 (en) 1995-07-20
SG47406A1 (en) 1998-04-17
EP0548024A3 (fr) 1994-03-23

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