DK0543713T3 - Hidtil ukendte ethanolaminbenzoatderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem - Google Patents

Hidtil ukendte ethanolaminbenzoatderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem

Info

Publication number
DK0543713T3
DK0543713T3 DK92403073.7T DK92403073T DK0543713T3 DK 0543713 T3 DK0543713 T3 DK 0543713T3 DK 92403073 T DK92403073 T DK 92403073T DK 0543713 T3 DK0543713 T3 DK 0543713T3
Authority
DK
Denmark
Prior art keywords
processes
preparation
benzoate derivatives
pharmaceutical agents
new
Prior art date
Application number
DK92403073.7T
Other languages
English (en)
Inventor
Pierre Hugon
Francoise Lacour
Michel Wierzbicki
Jacques Duhault
Michelle Boulanger
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0543713T3 publication Critical patent/DK0543713T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK92403073.7T 1991-11-22 1992-11-16 Hidtil ukendte ethanolaminbenzoatderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem DK0543713T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9114357A FR2684101B1 (fr) 1991-11-22 1991-11-22 Nouveaux derives de benzoate d'ethanolamine, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number Publication Date
DK0543713T3 true DK0543713T3 (da) 1995-07-24

Family

ID=9419177

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92403073.7T DK0543713T3 (da) 1991-11-22 1992-11-16 Hidtil ukendte ethanolaminbenzoatderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem

Country Status (13)

Country Link
US (1) US5266591A (da)
EP (1) EP0543713B1 (da)
JP (1) JPH0694447B2 (da)
AT (1) ATE118759T1 (da)
AU (1) AU649896B2 (da)
CA (1) CA2083475C (da)
DE (1) DE69201480T2 (da)
DK (1) DK0543713T3 (da)
ES (1) ES2072118T3 (da)
FR (1) FR2684101B1 (da)
GR (1) GR3015794T3 (da)
NZ (1) NZ245201A (da)
ZA (1) ZA928995B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2677647B1 (fr) * 1991-06-14 1993-08-20 Adir Nouveaux derives de benzoate d'ethanolamine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
WO1995011880A1 (en) * 1993-10-27 1995-05-04 Merck Sharp & Dohme Limited Substituted amides as tachykinin antagonists
US20080255093A1 (en) * 1999-06-14 2008-10-16 Tam Peter Y Compositions and methods for treating obesity and related disorders
US7553818B2 (en) * 1999-06-14 2009-06-30 Vivus, Inc. Combination therapy for effecting weight loss and treating obesity
US7674776B2 (en) * 1999-06-14 2010-03-09 Vivus, Inc. Combination therapy for effecting weight loss and treating obesity
US7056890B2 (en) * 1999-06-14 2006-06-06 Vivus, Inc. Combination therapy for effecting weight loss and treating obesity
US20080103179A1 (en) * 2006-10-27 2008-05-01 Tam Peter Y Combination Therapy
US7659256B2 (en) * 1999-06-14 2010-02-09 Vivus, Inc. Combination therapy for effecting weight loss and treating obesity
ES2542891T3 (es) * 1999-06-14 2015-08-12 Vivus, Inc. Terapia de combinación para el tratamiento de apnea del sueño asociada con la obesidad
US8580298B2 (en) * 2008-06-09 2013-11-12 Vivus, Inc. Low dose topiramate/phentermine composition and methods of use thereof
US20090304789A1 (en) 2008-06-09 2009-12-10 Thomas Najarian Novel topiramate compositions and an escalating dosing strategy for treating obesity and related disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1175516A (en) * 1966-04-15 1969-12-23 Science Union & Cie New Phenyl-Aminopropane Derivatives and Preparations Containing them
DE2629752A1 (de) * 1976-07-02 1978-01-05 Boehringer Mannheim Gmbh Neue carbonsaeurederivate und verfahren zu ihrer herstellung
US4237165A (en) * 1976-06-04 1980-12-02 Science Union Et Cie Treatment of carbohydrate metabolism disorders

Also Published As

Publication number Publication date
GR3015794T3 (en) 1995-07-31
EP0543713B1 (fr) 1995-02-22
US5266591A (en) 1993-11-30
CA2083475C (fr) 1998-09-08
NZ245201A (en) 1995-07-26
ATE118759T1 (de) 1995-03-15
JPH0694447B2 (ja) 1994-11-24
AU649896B2 (en) 1994-06-02
CA2083475A1 (fr) 1993-05-23
FR2684101A1 (fr) 1993-05-28
ZA928995B (en) 1993-05-25
JPH05221943A (ja) 1993-08-31
AU2854892A (en) 1993-05-27
FR2684101B1 (fr) 1993-12-31
ES2072118T3 (es) 1995-07-01
EP0543713A1 (fr) 1993-05-26
DE69201480D1 (de) 1995-03-30
DE69201480T2 (de) 1995-10-05

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