DK0542897T3 - Fremstilling af monoklonale antistoffer mod humant Vbeta-T-cellereceptorelement ved anvendelse af rekombinante DNA-vektorer - Google Patents

Fremstilling af monoklonale antistoffer mod humant Vbeta-T-cellereceptorelement ved anvendelse af rekombinante DNA-vektorer

Info

Publication number
DK0542897T3
DK0542897T3 DK91915852.7T DK91915852T DK0542897T3 DK 0542897 T3 DK0542897 T3 DK 0542897T3 DK 91915852 T DK91915852 T DK 91915852T DK 0542897 T3 DK0542897 T3 DK 0542897T3
Authority
DK
Denmark
Prior art keywords
human
monoclonal antibodies
recombinant dna
vbeta
dna vectors
Prior art date
Application number
DK91915852.7T
Other languages
Danish (da)
English (en)
Inventor
John Kappler
Philitpa Marrack
Yongwon Choi
Original Assignee
Nat Jewish Ct Immun & Respirat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Jewish Ct Immun & Respirat filed Critical Nat Jewish Ct Immun & Respirat
Application granted granted Critical
Publication of DK0542897T3 publication Critical patent/DK0542897T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK91915852.7T 1990-08-09 1991-08-08 Fremstilling af monoklonale antistoffer mod humant Vbeta-T-cellereceptorelement ved anvendelse af rekombinante DNA-vektorer DK0542897T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56543990A 1990-08-09 1990-08-09

Publications (1)

Publication Number Publication Date
DK0542897T3 true DK0542897T3 (da) 1997-02-17

Family

ID=24258606

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91915852.7T DK0542897T3 (da) 1990-08-09 1991-08-08 Fremstilling af monoklonale antistoffer mod humant Vbeta-T-cellereceptorelement ved anvendelse af rekombinante DNA-vektorer

Country Status (12)

Country Link
US (1) US5616472A (de)
EP (1) EP0542897B1 (de)
JP (1) JPH06502529A (de)
KR (1) KR930701620A (de)
AT (1) ATE148499T1 (de)
AU (1) AU652959B2 (de)
CA (1) CA2088905A1 (de)
DE (1) DE69124518T2 (de)
DK (1) DK0542897T3 (de)
ES (1) ES2098368T3 (de)
GR (1) GR3023102T3 (de)
WO (1) WO1992002629A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766947A (en) * 1988-12-14 1998-06-16 Astra Ab Monoclonal antibodies reactive with an epitope of a Vβ3.1 variable region of a T cell receptor
US5552300A (en) * 1994-01-13 1996-09-03 T Cell Sciences, Inc. T cell antigen receptor V region proteins and methods of preparation thereof
CA2305630C (en) * 1997-10-02 2012-11-06 Sunol Molecular Corporation Soluble single-chain t-cell receptor proteins
US6534633B1 (en) 1998-10-21 2003-03-18 Altor Bioscience Corporation Polyspecific binding molecules and uses thereof
US7927793B2 (en) * 2002-11-18 2011-04-19 The United States Of America As Represented By The Department Of Health And Human Services Cell lines and host nucleic acid sequences related to infectious disease
US11885807B2 (en) 2014-03-05 2024-01-30 Autolus Limited Method for depleting malignant T-cells
SG11201606583VA (en) * 2014-03-05 2016-09-29 Ucl Business Plc Chimeric antigen receptor (car) with antigen binding domains to the t cell receptor beta constant region
EA201792661A1 (ru) * 2015-06-01 2018-05-31 Медиджин Иммьюнотерапиз Гмбх Способ получения антител против т-клеточного рецептора
WO2016193299A1 (en) 2015-06-01 2016-12-08 Medigene Immunotherapies Gmbh T cell receptor library
MX2018007841A (es) 2015-12-23 2018-11-09 Medigene Immunotherapies Gmbh Composicion de celula dendritica.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189147A (en) * 1984-06-13 1993-02-23 Massachusetts Institute Of Technology Meterodimeric T lymphocyte receptor antibody
US5223426A (en) * 1988-12-15 1993-06-29 T Cell Sciences, Inc. Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor

Also Published As

Publication number Publication date
WO1992002629A1 (en) 1992-02-20
US5616472A (en) 1997-04-01
ATE148499T1 (de) 1997-02-15
EP0542897B1 (de) 1997-01-29
DE69124518D1 (de) 1997-03-13
AU652959B2 (en) 1994-09-15
ES2098368T3 (es) 1997-05-01
EP0542897A4 (en) 1993-08-18
AU8500691A (en) 1992-03-02
DE69124518T2 (de) 1997-05-15
JPH06502529A (ja) 1994-03-24
EP0542897A1 (de) 1993-05-26
CA2088905A1 (en) 1992-02-10
GR3023102T3 (en) 1997-07-30
KR930701620A (ko) 1993-06-12

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