DK0538810T3 - Anvendelse af interleukin-6 til fremstilling af et farmaceutisk præparat til behandling af lymfocytisk leukæmi og B-celle-l - Google Patents

Anvendelse af interleukin-6 til fremstilling af et farmaceutisk præparat til behandling af lymfocytisk leukæmi og B-celle-l

Info

Publication number
DK0538810T3
DK0538810T3 DK92117953T DK92117953T DK0538810T3 DK 0538810 T3 DK0538810 T3 DK 0538810T3 DK 92117953 T DK92117953 T DK 92117953T DK 92117953 T DK92117953 T DK 92117953T DK 0538810 T3 DK0538810 T3 DK 0538810T3
Authority
DK
Denmark
Prior art keywords
treatment
lymphocytic leukemia
cell
interleukin
preparation
Prior art date
Application number
DK92117953T
Other languages
English (en)
Inventor
Michel Bet Brazil Revel
David Wallach
Dan Aderka
Yasmin Maor
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Application granted granted Critical
Publication of DK0538810T3 publication Critical patent/DK0538810T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/204IL-6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK92117953T 1991-10-20 1992-10-20 Anvendelse af interleukin-6 til fremstilling af et farmaceutisk præparat til behandling af lymfocytisk leukæmi og B-celle-l DK0538810T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL9980391A IL99803A (en) 1991-10-20 1991-10-20 Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas

Publications (1)

Publication Number Publication Date
DK0538810T3 true DK0538810T3 (da) 1998-12-21

Family

ID=11062985

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92117953T DK0538810T3 (da) 1991-10-20 1992-10-20 Anvendelse af interleukin-6 til fremstilling af et farmaceutisk præparat til behandling af lymfocytisk leukæmi og B-celle-l

Country Status (12)

Country Link
US (1) US5462731A (da)
EP (1) EP0538810B1 (da)
JP (1) JP2823453B2 (da)
AT (1) ATE164077T1 (da)
AU (1) AU660493B2 (da)
CA (1) CA2080504C (da)
DE (1) DE69224786T2 (da)
DK (1) DK0538810T3 (da)
ES (1) ES2114903T3 (da)
GR (1) GR3026423T3 (da)
IL (1) IL99803A (da)
ZA (1) ZA927965B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021282A1 (en) * 1993-03-19 1994-09-29 Immunex Corporation Pharmaceutical compositions comprising a ligand complexed with a soluble receptor
US5641657A (en) * 1994-05-19 1997-06-24 Human Genome Sciences, Inc. DNA encoding an interleukin-6 splice variant
US6028050A (en) * 1996-11-27 2000-02-22 Tosoh Corporation Method for increasing platelets by administering soluble interleukin-6 receptor
IL122818A0 (en) 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
EP1317273B1 (en) * 2000-09-14 2006-05-03 Ares Trading S.A. Use of il-6r/il-6 chimera in huntington's disease
DE10107737A1 (de) * 2001-02-16 2002-09-05 S Rose John Christian Albrecht Verwendung eines Konjugats aus IL-6 und einem IL-6 Rezeptor zur Tumortherapie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990001943A2 (en) * 1988-08-26 1990-03-08 Schering Corporation Treatment of myeloid leukemias by inducing terminal differentiation with interleukin-6
AU639428B2 (en) * 1988-12-01 1993-07-29 Imclone Systems, Inc. Synthetic interleukin-6
JP2805224B2 (ja) * 1989-01-13 1998-09-30 味の素株式会社 血小板減少症治療剤
US5087448A (en) * 1989-02-02 1992-02-11 The Board Of Regents Of The University Of Oklahoma Enhancing growth of megakaryocytes in mammals using interleuking 6
US5216128A (en) * 1989-06-01 1993-06-01 Yeda Research And Development Co., Ltd. IFN-β2/IL-6 receptor its preparation and pharmaceutical compositions containing it

Also Published As

Publication number Publication date
US5462731A (en) 1995-10-31
ATE164077T1 (de) 1998-04-15
DE69224786D1 (de) 1998-04-23
IL99803A (en) 1997-02-18
GR3026423T3 (en) 1998-06-30
ES2114903T3 (es) 1998-06-16
IL99803A0 (en) 1992-08-18
EP0538810A2 (en) 1993-04-28
JPH0725785A (ja) 1995-01-27
AU660493B2 (en) 1995-06-29
AU2636592A (en) 1993-04-22
DE69224786T2 (de) 1998-07-09
JP2823453B2 (ja) 1998-11-11
CA2080504A1 (en) 1993-04-21
CA2080504C (en) 2006-10-03
ZA927965B (en) 1993-05-04
EP0538810B1 (en) 1998-03-18
EP0538810A3 (en) 1993-08-04

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