DK0534344T3 - Substituerede 3-amino-2,3,4,5-tetrahydro-1-aryl-oxy-3-benzazepiner, fremgangsmåde til deres fremstilling og deres anvendelse som modulatorer af neurotransmitterfunktionen - Google Patents

Substituerede 3-amino-2,3,4,5-tetrahydro-1-aryl-oxy-3-benzazepiner, fremgangsmåde til deres fremstilling og deres anvendelse som modulatorer af neurotransmitterfunktionen

Info

Publication number
DK0534344T3
DK0534344T3 DK92116111.3T DK92116111T DK0534344T3 DK 0534344 T3 DK0534344 T3 DK 0534344T3 DK 92116111 T DK92116111 T DK 92116111T DK 0534344 T3 DK0534344 T3 DK 0534344T3
Authority
DK
Denmark
Prior art keywords
modulators
hydrogen
benzazepines
tetrahydro
oxy
Prior art date
Application number
DK92116111.3T
Other languages
English (en)
Inventor
Richard Charles Effland
Joseph Thomas Klein
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of DK0534344T3 publication Critical patent/DK0534344T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK92116111.3T 1991-09-23 1992-09-21 Substituerede 3-amino-2,3,4,5-tetrahydro-1-aryl-oxy-3-benzazepiner, fremgangsmåde til deres fremstilling og deres anvendelse som modulatorer af neurotransmitterfunktionen DK0534344T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/763,711 US5202319A (en) 1991-09-23 1991-09-23 Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines

Publications (1)

Publication Number Publication Date
DK0534344T3 true DK0534344T3 (da) 1995-07-17

Family

ID=25068602

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92116111.3T DK0534344T3 (da) 1991-09-23 1992-09-21 Substituerede 3-amino-2,3,4,5-tetrahydro-1-aryl-oxy-3-benzazepiner, fremgangsmåde til deres fremstilling og deres anvendelse som modulatorer af neurotransmitterfunktionen

Country Status (8)

Country Link
US (1) US5202319A (da)
EP (1) EP0534344B1 (da)
JP (1) JP2665434B2 (da)
AT (1) ATE118484T1 (da)
DE (1) DE69201424T2 (da)
DK (1) DK0534344T3 (da)
ES (1) ES2068662T3 (da)
GR (1) GR3015494T3 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100710547B1 (ko) * 2002-01-02 2007-04-24 에스케이 주식회사 (ｓ)-3-아미노-2,3,4,5-테트라히드로-2-옥소-1Ｈ-벤자제핀-1-아세트산 및 이의 에스테르 화합물의 제조방법
KR100710548B1 (ko) * 2002-12-26 2007-04-24 에스케이 주식회사 (ｓ)-3-아미노-2,3,4,5-테트라히드로-2-옥소-1Ｈ-1-벤자제핀-1-아세트산 및 이의 에스테르 화합물의 제조방법
EP2146720A4 (en) 2007-05-10 2012-01-18 Amr Technology Inc ARYLOXY- AND HETEROARYLOXY-SUBSTITUTED TETRAHYDROBENZAZEPINE AND THEIR USE FOR THE RECOURSE-INHIBITION OF NOREPINEPHRIN, DOPAMINE AND SEROTONINE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
US4988690A (en) * 1982-06-14 1991-01-29 Hoechst-Roussel Pharmaceuticals Inc. 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant use thereof
US4794181A (en) * 1982-06-14 1988-12-27 Hoechst-Roussel Pharmaceuticals, Inc. 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines
ATE118002T1 (de) * 1989-08-02 1995-02-15 Hoechst Roussel Pharma 2,3-dihydro-1-(pyridinylamino)-indole, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.

Also Published As

Publication number Publication date
JP2665434B2 (ja) 1997-10-22
GR3015494T3 (en) 1995-06-30
ATE118484T1 (de) 1995-03-15
US5202319A (en) 1993-04-13
JPH05301859A (ja) 1993-11-16
ES2068662T3 (es) 1995-04-16
DE69201424D1 (de) 1995-03-23
DE69201424T2 (de) 1995-07-13
EP0534344B1 (en) 1995-02-15
EP0534344A1 (en) 1993-03-31

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