DK0523406T3 - Anvendelse af tri-(n-butyl)-phosphat ved lavt pH i opløsninger af biologisk aktive proteiner til forøget virucid virkning - Google Patents

Anvendelse af tri-(n-butyl)-phosphat ved lavt pH i opløsninger af biologisk aktive proteiner til forøget virucid virkning

Info

Publication number
DK0523406T3
DK0523406T3 DK92110522T DK92110522T DK0523406T3 DK 0523406 T3 DK0523406 T3 DK 0523406T3 DK 92110522 T DK92110522 T DK 92110522T DK 92110522 T DK92110522 T DK 92110522T DK 0523406 T3 DK0523406 T3 DK 0523406T3
Authority
DK
Denmark
Prior art keywords
tri
butyl
phosphate
solutions
low
Prior art date
Application number
DK92110522T
Other languages
English (en)
Inventor
Milton B Dobkin
George B Dove
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24917171&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0523406(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0523406T3 publication Critical patent/DK0523406T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261—Methods of inactivation or attenuation
    • C12N2760/20263—Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK92110522T 1991-07-05 1992-06-23 Anvendelse af tri-(n-butyl)-phosphat ved lavt pH i opløsninger af biologisk aktive proteiner til forøget virucid virkning DK0523406T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72608691A 1991-07-05 1991-07-05

Publications (1)

Publication Number Publication Date
DK0523406T3 true DK0523406T3 (da) 1999-08-16

Family

ID=24917171

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92110522T DK0523406T3 (da) 1991-07-05 1992-06-23 Anvendelse af tri-(n-butyl)-phosphat ved lavt pH i opløsninger af biologisk aktive proteiner til forøget virucid virkning

Country Status (8)

Country Link
EP (1) EP0523406B1 (da)
JP (1) JPH05184361A (da)
AT (1) ATE174383T1 (da)
CA (1) CA2072797C (da)
DE (1) DE69227805T2 (da)
DK (1) DK0523406T3 (da)
ES (1) ES2124235T3 (da)
GR (1) GR3029319T3 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06166634A (ja) * 1992-12-01 1994-06-14 Green Cross Corp:The プラスミノーゲン含有組成物の製造方法
US6034073A (en) * 1995-04-24 2000-03-07 Novavax, Inc. Solvent detergent emulsions having antiviral activity
US6686191B1 (en) * 1995-09-22 2004-02-03 Bayer Healthcare Llc Preparation of virally inactivated intravenously injectable immune serum globulin
US6225289B1 (en) * 1998-12-10 2001-05-01 Genvec, Inc. Methods and compositions for preserving adenoviral vectors
CN1302009C (zh) * 2005-09-05 2007-02-28 武汉海特生物制药股份有限公司 用有机溶剂病毒灭活法制备鼠神经生长因子的工艺
KR100791502B1 (ko) * 2006-09-29 2008-01-03 한스바이오메드 주식회사 바이러스 불활화된 무세포 인체 이식재 생산방법
JP5505853B2 (ja) 2007-02-13 2014-05-28 味の素株式会社 微酸性アルギニンを添加剤とするウイルス不活化法
CN108342368A (zh) * 2018-01-25 2018-07-31 武汉珈创生物技术股份有限公司 一种低pH孵育病毒灭活的验证方法
CN108535491B (zh) * 2018-03-22 2019-11-08 北京九强生物技术股份有限公司 一种肌钙蛋白i的胶乳增强免疫比浊检测试剂盒

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962421A (en) * 1973-06-18 1976-06-08 American Home Products Corporation Method for the disruption of lipid-containing viruses
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
DE3730533A1 (de) * 1987-09-11 1989-03-30 Biotest Pharma Gmbh Verfahren zur sterilisation von plasma oder plasmafraktionen
EP0378208B2 (en) * 1989-01-13 2003-01-15 Mitsubishi Pharma Corporation Production method for protein-containing composition
US5071650A (en) * 1990-06-04 1991-12-10 Miles Inc. Use of intermediate length alcohols as virucidal agents in solutions of biologically active proteins
US5110910A (en) * 1991-03-25 1992-05-05 Miles Inc. Virucidal euglobulin precipitation

Also Published As

Publication number Publication date
EP0523406B1 (en) 1998-12-09
DE69227805D1 (de) 1999-01-21
EP0523406A1 (en) 1993-01-20
CA2072797A1 (en) 1993-01-06
DE69227805T2 (de) 1999-04-29
ES2124235T3 (es) 1999-02-01
CA2072797C (en) 1998-10-06
ATE174383T1 (de) 1998-12-15
JPH05184361A (ja) 1993-07-27
GR3029319T3 (en) 1999-05-28

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