DK0457215T3 - 3-deamino-4-desoxy-4-amino-8-fluoranthracycliner samt fremgangsmåder til fremstilling deraf - Google Patents
3-deamino-4-desoxy-4-amino-8-fluoranthracycliner samt fremgangsmåder til fremstilling derafInfo
- Publication number
- DK0457215T3 DK0457215T3 DK91107628.9T DK91107628T DK0457215T3 DK 0457215 T3 DK0457215 T3 DK 0457215T3 DK 91107628 T DK91107628 T DK 91107628T DK 0457215 T3 DK0457215 T3 DK 0457215T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- fluoroanthracyclines
- deamino
- deoxy
- amino
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/244—Anthraquinone radicals, e.g. sennosides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20300A IT1241927B (it) | 1990-05-14 | 1990-05-14 | 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0457215T3 true DK0457215T3 (da) | 1996-06-10 |
Family
ID=11165542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91107628.9T DK0457215T3 (da) | 1990-05-14 | 1991-05-10 | 3-deamino-4-desoxy-4-amino-8-fluoranthracycliner samt fremgangsmåder til fremstilling deraf |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5807835A (cs) |
| EP (1) | EP0457215B1 (cs) |
| JP (1) | JPH04226972A (cs) |
| KR (1) | KR910020025A (cs) |
| CN (1) | CN1031192C (cs) |
| AT (1) | ATE133177T1 (cs) |
| AU (1) | AU638574B2 (cs) |
| BR (1) | BR9101973A (cs) |
| CA (1) | CA2042463A1 (cs) |
| CS (1) | CS135891A3 (cs) |
| DE (1) | DE69116423T2 (cs) |
| DK (1) | DK0457215T3 (cs) |
| ES (1) | ES2084724T3 (cs) |
| FI (1) | FI912269A7 (cs) |
| GR (1) | GR3018716T3 (cs) |
| HU (1) | HU209458B (cs) |
| IE (1) | IE911634A1 (cs) |
| IL (1) | IL98117A0 (cs) |
| IT (1) | IT1241927B (cs) |
| MA (1) | MA22153A1 (cs) |
| MX (1) | MX25747A (cs) |
| NO (1) | NO174963C (cs) |
| PL (1) | PL290236A1 (cs) |
| PT (1) | PT97663B (cs) |
| RO (1) | RO108792B1 (cs) |
| RU (1) | RU2095365C1 (cs) |
| TN (1) | TNSN91036A1 (cs) |
| TW (1) | TW228524B (cs) |
| YU (1) | YU83691A (cs) |
| ZA (1) | ZA913644B (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1262565B (it) * | 1993-09-30 | 1996-07-04 | Menarini Farma Ind | Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono. |
| US6143864A (en) * | 1994-06-28 | 2000-11-07 | Merck & Co., Inc. | Peptides |
| IT1271689B (it) * | 1994-08-04 | 1997-06-04 | Menarini Farma Ind | 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono |
| US8357785B2 (en) * | 2008-01-08 | 2013-01-22 | Solux Corporation | Method of aralkylation of 4′-hydroxyl group of anthracylins |
| CN104098628B (zh) * | 2014-07-31 | 2017-07-18 | 大连大学 | 一类n‑三氟乙酰柔红霉素的硒代衍生物，其制备方法及应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663445A (en) * | 1985-03-20 | 1987-05-05 | The Ohio State Research Foundation | 1-fluoro, 4-fluoro, and 1,4-difluoro-2'-halo anthracycline antibiotics |
| GB8803076D0 (en) * | 1988-02-10 | 1988-03-09 | Erba Carlo Spa | 3'-deamino-4'-deoxy-4'-amino anthracyclines |
| GB8902709D0 (en) * | 1989-02-07 | 1989-03-30 | Erba Carlo Spa | New 4'-epi-4'-amino anthracyclines |
-
1990
- 1990-05-14 IT IT20300A patent/IT1241927B/it active IP Right Grant
-
1991
- 1991-05-08 NO NO911798A patent/NO174963C/no unknown
- 1991-05-08 CS CS911358A patent/CS135891A3/cs unknown
- 1991-05-10 AT AT91107628T patent/ATE133177T1/de active
- 1991-05-10 DK DK91107628.9T patent/DK0457215T3/da active
- 1991-05-10 MX MX25747A patent/MX25747A/es unknown
- 1991-05-10 EP EP91107628A patent/EP0457215B1/en not_active Expired - Lifetime
- 1991-05-10 DE DE69116423T patent/DE69116423T2/de not_active Expired - Fee Related
- 1991-05-10 FI FI912269A patent/FI912269A7/fi not_active Application Discontinuation
- 1991-05-10 ES ES91107628T patent/ES2084724T3/es not_active Expired - Lifetime
- 1991-05-13 PL PL29023691A patent/PL290236A1/xx unknown
- 1991-05-13 IE IE163491A patent/IE911634A1/en unknown
- 1991-05-13 RU SU914895527A patent/RU2095365C1/ru active
- 1991-05-13 CA CA002042463A patent/CA2042463A1/en not_active Abandoned
- 1991-05-13 IL IL98117A patent/IL98117A0/xx unknown
- 1991-05-13 AU AU76493/91A patent/AU638574B2/en not_active Ceased
- 1991-05-13 TW TW080103704A patent/TW228524B/zh active
- 1991-05-13 YU YU83691A patent/YU83691A/sh unknown
- 1991-05-13 MA MA22423A patent/MA22153A1/fr unknown
- 1991-05-13 HU HU911595A patent/HU209458B/hu not_active IP Right Cessation
- 1991-05-14 KR KR1019910007747A patent/KR910020025A/ko not_active Withdrawn
- 1991-05-14 BR BR919101973A patent/BR9101973A/pt not_active Application Discontinuation
- 1991-05-14 ZA ZA913644A patent/ZA913644B/xx unknown
- 1991-05-14 TN TNTNSN91036A patent/TNSN91036A1/fr unknown
- 1991-05-14 US US07/699,898 patent/US5807835A/en not_active Expired - Fee Related
- 1991-05-14 RO RO147541A patent/RO108792B1/ro unknown
- 1991-05-14 JP JP3136954A patent/JPH04226972A/ja active Pending
- 1991-05-14 PT PT97663A patent/PT97663B/pt not_active IP Right Cessation
- 1991-05-14 CN CN91103091A patent/CN1031192C/zh not_active Expired - Fee Related
-
1996
- 1996-01-18 GR GR950403698T patent/GR3018716T3/el unknown
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