DK0456107T3 - Fremgangsmåde til enzymatisk reduktion af oxo-forbindelser, især acetophenon, og dertil egnet enzym - Google Patents
Fremgangsmåde til enzymatisk reduktion af oxo-forbindelser, især acetophenon, og dertil egnet enzymInfo
- Publication number
- DK0456107T3 DK0456107T3 DK91107067.0T DK91107067T DK0456107T3 DK 0456107 T3 DK0456107 T3 DK 0456107T3 DK 91107067 T DK91107067 T DK 91107067T DK 0456107 T3 DK0456107 T3 DK 0456107T3
- Authority
- DK
- Denmark
- Prior art keywords
- suitable enzymes
- enzymatic reduction
- oxo compounds
- acetophenone
- especially acetophenone
- Prior art date
Links
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 title 2
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 230000002255 enzymatic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4014573A DE4014573C1 (enExample) | 1990-05-07 | 1990-05-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0456107T3 true DK0456107T3 (da) | 1996-03-25 |
Family
ID=6405860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91107067.0T DK0456107T3 (da) | 1990-05-07 | 1991-05-02 | Fremgangsmåde til enzymatisk reduktion af oxo-forbindelser, især acetophenon, og dertil egnet enzym |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5200335A (enExample) |
| EP (1) | EP0456107B1 (enExample) |
| JP (1) | JP2767164B2 (enExample) |
| CA (1) | CA2041837C (enExample) |
| DE (2) | DE4014573C1 (enExample) |
| DK (1) | DK0456107T3 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3574682B2 (ja) * | 1993-09-24 | 2004-10-06 | ダイセル化学工業株式会社 | 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法 |
| DE19610984A1 (de) * | 1996-03-21 | 1997-09-25 | Boehringer Mannheim Gmbh | Alkohol-Dehydrogenase und deren Verwendung zur enzymatischen Herstellung chiraler Hydroxyverbindungen |
| EP1067195B1 (de) * | 1999-07-09 | 2006-09-20 | Forschungszentrum Jülich Gmbh | Verfahren zur Reduktion von Ketogruppen enthaltende Verbindungen |
| WO2001004336A1 (de) * | 1999-07-09 | 2001-01-18 | Forschungszentrum Jülich GmbH | Verfahren zur reduktion von keto-carbonsäuren und deren estern |
| DE19937825B4 (de) * | 1999-07-09 | 2005-08-11 | Forschungszentrum Jülich GmbH | Verfahren zur Reduktion von Hydroxyketo-Carbonsäuren und deren Estern |
| DE10002975A1 (de) * | 2000-01-24 | 2001-07-26 | Degussa | Verwendung von molekulargewichtsvergrößerten Katalysatoren in einem Verfahren zur asymmetrischen kontinuierlichen Hydrierung, neue molekulargewichtsvergrößerte Liganden und Katalysatoren |
| DE10119274A1 (de) | 2001-04-20 | 2002-10-31 | Juelich Enzyme Products Gmbh | Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen |
| FR2826650A1 (fr) * | 2001-07-02 | 2003-01-03 | Rhodia Chimie Sa | Procede de reduction enantioselectif d'une cetone aromatique prochirale comprenant au moins un groupe trifluoromethyle sur le cycle aromatique |
| DE102004007029A1 (de) * | 2004-02-12 | 2005-09-08 | Consortium für elektrochemische Industrie GmbH | Verfahren zur enantioselektiven Reduktion von Ketoverbindungen durch Enzyme |
| AT502395B1 (de) | 2005-07-27 | 2007-03-15 | Iep Gmbh | Oxidoreduktasen zur stereoselektiven reduktion von ketoverbindungen |
| AT502185B1 (de) * | 2005-09-23 | 2007-02-15 | Iep Gmbh | Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen |
| AT503486B1 (de) * | 2006-04-11 | 2008-05-15 | Iep Gmbh | Verfahren zur enantioselektiven reduktion von steroiden |
| US7795004B2 (en) * | 2006-04-21 | 2010-09-14 | Basf Se | Process for the racemization of optically active secondary alcohols with the use of two alcohol dehydrogenases |
| WO2008042876A2 (en) | 2006-10-02 | 2008-04-10 | Codexis, Inc. | Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor |
| AT504542B1 (de) | 2006-12-07 | 2008-09-15 | Iep Gmbh | Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten |
| EP2115130B1 (en) | 2007-02-08 | 2011-08-03 | Codexis, Inc. | Ketoreductases and uses thereof |
| JP2010536385A (ja) * | 2007-08-24 | 2010-12-02 | コデクシス， インコーポレイテッド | （ｒ）−３−ヒドロキシチオランの立体選択的生成のための改善されたケトレダクターゼポリペプチド |
| EP2198018B1 (en) | 2007-09-13 | 2013-11-20 | Codexis, Inc. | Ketoreductase polypeptides for the reduction of acetophenones |
| TWI601825B (zh) * | 2007-09-27 | 2017-10-11 | Ｉｅｐ有限公司 | 對映異構選擇性酶催化還原中間產物之方法 |
| EP2203557B1 (en) * | 2007-09-28 | 2012-02-29 | Codexis, Inc. | Ketoreductase polypeptides and uses thereof |
| HUE027683T2 (en) | 2007-10-01 | 2016-10-28 | Codexis Inc | Ketoreductase polypeptides for the production of azetidinone |
| EP2329013B1 (en) | 2008-08-27 | 2015-10-28 | Codexis, Inc. | Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
| WO2010025287A2 (en) | 2008-08-27 | 2010-03-04 | Codexis, Inc. | Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
| US8273554B2 (en) | 2008-08-29 | 2012-09-25 | Codexis, Inc. | Ketoreductase polypeptides for the stereoselective production of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one |
| DE102008054918A1 (de) | 2008-12-18 | 2010-07-01 | Evonik Degussa Gmbh | Verfahren zur enzymatischen Umsetzung von Alkanen |
| EP2226386A1 (de) | 2009-03-05 | 2010-09-08 | IEP GmbH | Verfahren zur stereoselektiven enzymatischen Reduktion von Ketoverbindungen |
| ES2575560T3 (es) | 2009-08-19 | 2016-06-29 | Codexis, Inc. | Polipéptidos cetorreductasa para preparar fenilefrina |
| HUE026367T2 (en) | 2010-05-04 | 2016-06-28 | Codexis Inc | Biocatalysts for ezetimibe synthesis |
| US9096825B2 (en) | 2010-05-27 | 2015-08-04 | Pharmazell Gmbh | 7 α-hydroxysteroid dehydrogenase knockout mutants and use therefor |
| DE102013104418B4 (de) | 2013-04-30 | 2018-09-27 | Cambrex Iep Gmbh | Biokatalytisches Verfahren für die Herstellung von (R)-3-Chinuclidinol |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60128289A (ja) | 1983-12-12 | 1985-07-09 | Orient Watch Co Ltd | 複合めつき方法 |
| JPS61285993A (ja) | 1985-06-14 | 1986-12-16 | Idemitsu Kosan Co Ltd | フェナシルアルコ−ル類の製造方法 |
-
1990
- 1990-05-07 DE DE4014573A patent/DE4014573C1/de not_active Expired - Lifetime
-
1991
- 1991-05-02 DE DE59107265T patent/DE59107265D1/de not_active Expired - Lifetime
- 1991-05-02 DK DK91107067.0T patent/DK0456107T3/da active
- 1991-05-02 EP EP91107067A patent/EP0456107B1/de not_active Expired - Lifetime
- 1991-05-06 US US07/694,988 patent/US5200335A/en not_active Expired - Lifetime
- 1991-05-07 CA CA002041837A patent/CA2041837C/en not_active Expired - Lifetime
- 1991-05-07 JP JP3101658A patent/JP2767164B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2041837A1 (en) | 1991-11-08 |
| EP0456107B1 (de) | 1996-01-17 |
| JPH04330278A (ja) | 1992-11-18 |
| JP2767164B2 (ja) | 1998-06-18 |
| EP0456107A2 (de) | 1991-11-13 |
| US5200335A (en) | 1993-04-06 |
| CA2041837C (en) | 2002-06-18 |
| DE59107265D1 (de) | 1996-02-29 |
| EP0456107A3 (en) | 1992-03-25 |
| DE4014573C1 (enExample) | 1991-10-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0456107T3 (da) | Fremgangsmåde til enzymatisk reduktion af oxo-forbindelser, især acetophenon, og dertil egnet enzym | |
| NO850011L (no) | Fremgangsmaate til foring av roerledniner o.l., og foring til utfoerelse av fremgangsmaaten | |
| FI843837A7 (fi) | Entsyymi-inhibiittorit. | |
| DK358885A (da) | Enzymatisk detergentadditiv, detergent og vaskeproces | |
| KR890701022A (ko) | 에치아이브의 선택적 저해방법 | |
| FI875043A7 (fi) | Menetelmä bioteknisten prosessien suorittamiseksi | |
| FI844684A7 (fi) | Menetelmä sellulolyyttisten entsyymien valmistamiseksi. | |
| DK0565168T3 (da) | Fremgangsmåde til fremstilling af oprenset enzym | |
| DK0780466T4 (da) | Enzymholdigt granulat, fremgangsmåde til dets fremstilling og sammensætninger, der indeholder det | |
| DK120284A (da) | Fremgangsmaade til fermentering af en enzymproducerende mikroorganisme, der kan producere protease og amylase | |
| IT1209526B (it) | Metodo per il trattamento enzimatico di polpa pre-spremuta. | |
| DK160997C (da) | Immobiliseret, enzymatisk aktiv substans og fremgangsmaade til fremstilling af samme | |
| DE3784099D1 (de) | Enzym und verfahren zu seiner herstellung. | |
| IT1208519B (it) | Procedimento di purificazione di un enzima. | |
| DE3485210D1 (de) | Immobilisierte enzymzusammensetzungen. | |
| DK0421477T3 (da) | Enzymatisk fremgangsmåde til fremstilling af L-serin | |
| FI914049A7 (fi) | Menetelmä entsyymien erottamiseksi entsyymipitoisista liuoksista | |
| DK0631733T3 (da) | Enzymatisk middel til forbedring af mørningen af kød | |
| FI840557A7 (fi) | Immobilisoitujen entsyymien tuottaminen. | |
| NO166716C (no) | Peptidderivater og anvendelse derav som substrater for kvantitativ bestemmelse av enzymer. | |
| DE3880290D1 (de) | Enzym und verfahren zu seiner herstellung. | |
| FI953728L (fi) | Parannettu menetelmä kefakloorin eristämiseksi entsymaattisen asyloinnin jälkeen | |
| NO890402L (no) | Human-immundefisient virus-spesifikt proteolytisk enzym og fremgangsmaate for dets syntese og renaturering. | |
| DK450088A (da) | Enzymatisk middel til vask, affedtning og vandrekonditionering | |
| ATE85645T1 (de) | Enzym und verfahren zu seiner herstellung. |