DK0432254T3 - Nucleinsyre, som koder for humant testikulært angiotensinomdannende enzym (ACE), og dens anvendelser, især til påvisning in vitro af dette enzym i organismen - Google Patents
Nucleinsyre, som koder for humant testikulært angiotensinomdannende enzym (ACE), og dens anvendelser, især til påvisning in vitro af dette enzym i organismenInfo
- Publication number
- DK0432254T3 DK0432254T3 DK90910749T DK90910749T DK0432254T3 DK 0432254 T3 DK0432254 T3 DK 0432254T3 DK 90910749 T DK90910749 T DK 90910749T DK 90910749 T DK90910749 T DK 90910749T DK 0432254 T3 DK0432254 T3 DK 0432254T3
- Authority
- DK
- Denmark
- Prior art keywords
- ace
- enzyme
- nucleic acid
- organism
- applications
- Prior art date
Links
- 230000002381 testicular Effects 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 238000000338 in vitro Methods 0.000 title abstract 2
- UUUHXMGGBIUAPW-UHFFFAOYSA-N 1-[1-[2-[[5-amino-2-[[1-[5-(diaminomethylideneamino)-2-[[1-[3-(1h-indol-3-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbon Chemical compound C1CCC(C(=O)N2C(CCC2)C(O)=O)N1C(=O)C(C(C)CC)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C1CCC(=O)N1 UUUHXMGGBIUAPW-UHFFFAOYSA-N 0.000 title 2
- 102000004270 Peptidyl-Dipeptidase A Human genes 0.000 title 2
- 108090000882 Peptidyl-Dipeptidase A Proteins 0.000 title 2
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 238000010367 cloning Methods 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 238000012163 sequencing technique Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8909062A FR2649412B1 (fr) | 1989-07-05 | 1989-07-05 | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) testiculaire humaine, et ses applications, notamment pour le depistage in vitro de cette enzyme dans l'organisme |
| PCT/FR1990/000513 WO1991000354A1 (fr) | 1989-07-05 | 1990-07-05 | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) testiculaire humaine, et ses applications, notamment pour le depistage in vitro de cette enzyme dans l'organisme |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0432254T3 true DK0432254T3 (da) | 2003-08-11 |
Family
ID=9383508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90910749T DK0432254T3 (da) | 1989-07-05 | 1990-07-05 | Nucleinsyre, som koder for humant testikulært angiotensinomdannende enzym (ACE), og dens anvendelser, især til påvisning in vitro af dette enzym i organismen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5801040A (da) |
| EP (1) | EP0432254B1 (da) |
| JP (1) | JPH04500612A (da) |
| AT (1) | ATE238423T1 (da) |
| CA (1) | CA2035888C (da) |
| DE (1) | DE69034060T2 (da) |
| DK (1) | DK0432254T3 (da) |
| ES (1) | ES2195992T3 (da) |
| FR (1) | FR2649412B1 (da) |
| WO (1) | WO1991000354A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2678285A1 (fr) * | 1991-06-27 | 1992-12-31 | Inst Nat Sante Rech Med | Moyens et procedes pour l'etude du polymorphisme genetique de l'enzyme de conversion de l'angiotensine 1. |
| WO1999015643A2 (en) * | 1997-09-25 | 1999-04-01 | University Of Florida | ANTISENSE OLIGONUCLEOTIDE COMPOSITIONS TARGETED TO ANGIOTENSI N CONVERTING ENZYME mRNA AND METHODS OF USE |
| US6989363B1 (en) * | 1997-12-11 | 2006-01-24 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor |
| US6194556B1 (en) | 1997-12-11 | 2001-02-27 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor |
| US6610497B1 (en) * | 1997-12-11 | 2003-08-26 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor |
| US6525185B1 (en) * | 1998-05-07 | 2003-02-25 | Affymetrix, Inc. | Polymorphisms associated with hypertension |
| US6280994B1 (en) * | 1998-11-25 | 2001-08-28 | Zymogenetics, Inc. | Zace 1: a human metalloenzyme |
| AU4691900A (en) * | 1999-05-13 | 2000-12-05 | Zymogenetics Inc. | Zace2: a human metalloenzyme |
| GB0221169D0 (en) * | 2002-09-12 | 2002-10-23 | Univ Bath | Crystal |
| US7407933B2 (en) | 2002-10-29 | 2008-08-05 | Gen Kondoh | Drug containing angiotensin convertase |
| GB0600406D0 (en) | 2006-01-10 | 2006-02-15 | Univ Bath | Crystal |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4276378A (en) * | 1977-11-25 | 1981-06-30 | Ryan James W | High sensitivity assays for angiotensin converting enzyme |
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
-
1989
- 1989-07-05 FR FR8909062A patent/FR2649412B1/fr not_active Expired - Fee Related
-
1990
- 1990-07-05 WO PCT/FR1990/000513 patent/WO1991000354A1/fr active IP Right Grant
- 1990-07-05 JP JP2510307A patent/JPH04500612A/ja active Pending
- 1990-07-05 ES ES90910749T patent/ES2195992T3/es not_active Expired - Lifetime
- 1990-07-05 DK DK90910749T patent/DK0432254T3/da active
- 1990-07-05 EP EP90910749A patent/EP0432254B1/fr not_active Expired - Lifetime
- 1990-07-05 DE DE69034060T patent/DE69034060T2/de not_active Expired - Fee Related
- 1990-07-05 CA CA002035888A patent/CA2035888C/fr not_active Expired - Lifetime
- 1990-07-05 AT AT90910749T patent/ATE238423T1/de not_active IP Right Cessation
-
1995
- 1995-06-07 US US08/481,626 patent/US5801040A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2195992T3 (es) | 2003-12-16 |
| EP0432254B1 (fr) | 2003-04-23 |
| DE69034060T2 (de) | 2004-02-26 |
| WO1991000354A1 (fr) | 1991-01-10 |
| FR2649412B1 (fr) | 1995-10-20 |
| ATE238423T1 (de) | 2003-05-15 |
| JPH04500612A (ja) | 1992-02-06 |
| FR2649412A1 (fr) | 1991-01-11 |
| US5801040A (en) | 1998-09-01 |
| EP0432254A1 (fr) | 1991-06-19 |
| DE69034060D1 (de) | 2003-05-28 |
| CA2035888C (fr) | 2006-11-28 |
| CA2035888A1 (fr) | 1991-01-06 |
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