DK0397031T3 - Hidtil ukendte phenylalkansyreestere - Google Patents

Hidtil ukendte phenylalkansyreestere

Info

Publication number
DK0397031T3
DK0397031T3 DK90108375.8T DK90108375T DK0397031T3 DK 0397031 T3 DK0397031 T3 DK 0397031T3 DK 90108375 T DK90108375 T DK 90108375T DK 0397031 T3 DK0397031 T3 DK 0397031T3
Authority
DK
Denmark
Prior art keywords
nitrogen
alkyl
hydrogen
taken together
attached
Prior art date
Application number
DK90108375.8T
Other languages
English (en)
Inventor
Sadahiko Iguchi
Masanori Kawamura
Tsumoru Miyamoto
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Application granted granted Critical
Publication of DK0397031T3 publication Critical patent/DK0397031T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK90108375.8T 1989-05-12 1990-05-03 Hidtil ukendte phenylalkansyreestere DK0397031T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11987389 1989-05-12

Publications (1)

Publication Number Publication Date
DK0397031T3 true DK0397031T3 (da) 1994-10-31

Family

ID=14772367

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90108375.8T DK0397031T3 (da) 1989-05-12 1990-05-03 Hidtil ukendte phenylalkansyreestere

Country Status (9)

Country Link
US (1) US5013734A (da)
EP (1) EP0397031B1 (da)
JP (2) JPH0730068B2 (da)
KR (1) KR970003457B1 (da)
AT (1) ATE108788T1 (da)
CA (1) CA2015730C (da)
DE (1) DE69010757T2 (da)
DK (1) DK0397031T3 (da)
ES (1) ES2060853T3 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ335566A (en) 1995-10-10 2003-01-31 Univ Melbourne 3-amino-propoxyphenyl derivatives (I) and use in treating cardiac conditions as a beta blocker
WO2005014042A1 (ja) 2003-08-08 2005-02-17 Ono Pharmaceutical Co., Ltd. 短時間型β遮断薬を有効成分とする心拍数減少剤
ITMI20110343A1 (it) * 2011-03-04 2012-09-05 Procos Spa Processo per la sintesi enantioselettiva di landiolol
ES2532851T3 (es) 2012-07-20 2015-04-01 Procos S.P.A. Proceso para la síntesis enantioselectiva de landiolol
CN104003973B (zh) * 2014-06-05 2016-02-24 重庆植恩药业有限公司 一种兰地洛尔草酸盐的制备方法
CN106608863A (zh) * 2015-10-23 2017-05-03 北京创立科创医药技术开发有限公司 一种盐酸兰地洛尔的制备方法
CN106248825B (zh) * 2016-07-21 2017-10-10 山东省分析测试中心 盐酸兰地洛尔原料药物中起始物料a的检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8004087L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ...
ZA827646B (en) * 1981-11-12 1983-08-31 American Hospital Supply Corp Esters of aryloxypropanolamine derivatives
US4548941A (en) * 1984-07-30 1985-10-22 Merck & Co., Inc. 1,5-Methano-1H-4-benzazonine dicarboxylates, process for preparing and use as calcium blockers
GB2169892B (en) * 1985-01-23 1988-02-03 Ferrer Int Piperazine derivatives

Also Published As

Publication number Publication date
ES2060853T3 (es) 1994-12-01
CA2015730C (en) 1997-10-07
EP0397031A1 (en) 1990-11-14
DE69010757D1 (de) 1994-08-25
EP0397031B1 (en) 1994-07-20
DE69010757T2 (de) 1994-12-15
JPH0372475A (ja) 1991-03-27
US5013734A (en) 1991-05-07
CA2015730A1 (en) 1990-11-12
ATE108788T1 (de) 1994-08-15
KR900018082A (ko) 1990-12-20
JPH0730068B2 (ja) 1995-04-05
JPH0673044A (ja) 1994-03-15
KR970003457B1 (ko) 1997-03-18
JP2539734B2 (ja) 1996-10-02

Similar Documents

Publication Publication Date Title
DE3773660D1 (de) Morpholinoethylester von mycophenolsaeure und ihre derivate, ihre herstellung und verwendung in pharmazeutische zusammensetzungen.
KR101136434B1 (ko) 향상된 항염증성, 항혈전성 및 항혈소판 활성을 가진콜레스테롤을 낮추는 물질로서의 플루바스타틴,프라바스타틴, 세리바스타틴, 아토르바스타틴 및로수바스타틴의 니트록시유도체들
NO174296C (no) Analogifremgangsmåte til fremstilling av terapeutisk aktive 1-indolylalkyl-4-(substituert-pyridinyl)piperaziner
FR2697524B1 (fr) Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
CA2065644A1 (en) Pyrazolopyridine compound and processes for preparation thereof
DE69701298D1 (de) Hydroxypyridin-Derivate, ihre Herstellung und ihre pharmazeutische Verwendung
FI940414A0 (fi) Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö
DK0430201T3 (da)
DK0397031T3 (da) Hidtil ukendte phenylalkansyreestere
ATE67193T1 (de) 6-phenyl-pyridazin-verbindungen.
GB8809481D0 (en) Chemical compounds
MX9202975A (es) Nuevos compuestos biciclicos y sus sales farmaceuticamente aceptables y procedimiento para su preparacion.
NO172939C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive estere av estramustin
NO942568D0 (no) 1-aryloksy-3-alkylamino-2-propanolitratestere, deres anvendelse og tilsvarende farmasöytiske blanding
GB1530768A (en) 2-substituted-4-amino-6,7-dimethoxyquinazolines
IL96762A0 (en) Pyridyl cyclopropane derivatives,process for their preparation and fungicidal compositions containing them
EA200100816A1 (ru) 2-аминопиридины, содержащие конденсированные кольца в качестве заместителей
TW372967B (en) 1,4 benzoxazine derivative, pharmaceutical composition containing the same and use thereof
IT1205640B (it) Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
EA199900836A1 (ru) Противосудорожные производные изохинолилбензамида
US4833162A (en) Substituted benzeneacetonitriles and their use as calcium channel blockers
IT1212722B (it) Derivato dell'acido benzoico.
JPS55105620A (en) Calcium antagonist
ATE58730T1 (de) Benzoxathiin-derivate, verfahren zu deren herstellung und pharmazeutische zusammenstellungen.
JPS55105619A (en) Calcium antagonist