DK0394035T3 - Gener, der koder for et protein med human MACIF-aktivitet, ekspressionsvektorer indeholdende disse gener, transformantceller og proteiner med human MACIF-aktivitet - Google Patents

Gener, der koder for et protein med human MACIF-aktivitet, ekspressionsvektorer indeholdende disse gener, transformantceller og proteiner med human MACIF-aktivitet

Info

Publication number
DK0394035T3
DK0394035T3 DK90304203.4T DK90304203T DK0394035T3 DK 0394035 T3 DK0394035 T3 DK 0394035T3 DK 90304203 T DK90304203 T DK 90304203T DK 0394035 T3 DK0394035 T3 DK 0394035T3
Authority
DK
Denmark
Prior art keywords
genes
human macif
macif activity
protein
activity
Prior art date
Application number
DK90304203.4T
Other languages
English (en)
Inventor
Motowo Tomita
Yuji Sugita
Toshiyuki Takemoto
Kiyoshi Furuichi
Makoto Takayama
Ko Yusakawa
Shinya Yano
Noboru Yamaji
Katsuhisa Ito
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Application granted granted Critical
Publication of DK0394035T3 publication Critical patent/DK0394035T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK90304203.4T 1989-04-21 1990-04-19 Gener, der koder for et protein med human MACIF-aktivitet, ekspressionsvektorer indeholdende disse gener, transformantceller og proteiner med human MACIF-aktivitet DK0394035T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP10308889 1989-04-21
JP17993389 1989-07-12
JP23098389 1989-09-06
JP23824689 1989-09-13
JP24781889 1989-09-21
JP28119789 1989-10-27

Publications (1)

Publication Number Publication Date
DK0394035T3 true DK0394035T3 (da) 1996-05-13

Family

ID=27552152

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90304203.4T DK0394035T3 (da) 1989-04-21 1990-04-19 Gener, der koder for et protein med human MACIF-aktivitet, ekspressionsvektorer indeholdende disse gener, transformantceller og proteiner med human MACIF-aktivitet

Country Status (12)

Country Link
US (1) US5532339A (da)
EP (2) EP0394035B1 (da)
JP (1) JP2828148B2 (da)
KR (1) KR0150000B1 (da)
AT (2) ATE202570T1 (da)
AU (1) AU640643B2 (da)
CA (1) CA2014948C (da)
DE (2) DE69024693T2 (da)
DK (1) DK0394035T3 (da)
ES (1) ES2084658T3 (da)
GR (1) GR3019347T3 (da)
IE (2) IE960874L (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795736A (en) * 1989-04-21 1998-08-18 Yamanouchi Pharmaceutical Co., Ltd. Genes coding for a protein having human MACIF activity, expression vectors containing said genes, transformant cells and proteins having human macif activity
US5573940A (en) * 1989-06-12 1996-11-12 Oklahoma Medical Research Foundation Cells expressing high levels of CD59
AU6015696A (en) * 1995-06-16 1997-01-15 Yamanouchi Pharmaceutical Co., Ltd. Modified polypeptide, dna encoding the same, transformant, and medicinal composition containing the polypeptide
US7166568B1 (en) 1998-02-09 2007-01-23 Oklahoma Medical Research Foundation Compositions and methods to inhibit formation of the C5b-9 complex of complement
WO2001010908A1 (en) * 1999-08-04 2001-02-15 Amgen Inc. Ntr3, a member of the tnf-receptor supergene family
US6835545B2 (en) 2000-05-08 2004-12-28 President And Fellows Of Harvard College Methods, products and treatments for diabetes
US7439330B2 (en) 2000-05-08 2008-10-21 President And Fellows Of Harvard College Anti-glycated CD59 antibodies and uses thereof
CN1325889A (zh) * 2000-05-26 2001-12-12 上海博德基因开发有限公司 一种新的多肽——人Kazal型抑制因子11和编码这种多肽的多核苷酸
US7833725B2 (en) 2005-01-06 2010-11-16 President And Fellows Of Harvard College Mass spectrometric methods and products
AU2015202046B2 (en) * 2008-02-15 2017-06-29 Tufts University A humanized model of membrane attack complex (mac) formation on murine retina and compositions, kits and methods for treatment of macular degeneration
CA2843684A1 (en) * 2010-08-13 2012-02-16 Tufts University Compositions, kits and methods for treatment of macular degeneration using soluble membrane-independent cd59 protein
US9068006B2 (en) 2010-08-25 2015-06-30 President And Fellows Of Harvard College Glycated CD59 peptides, their preparation, and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109113A (en) * 1986-05-02 1992-04-28 Genentech, Inc. Membrane anchor fusion polypeptides
US5179198A (en) * 1988-07-11 1993-01-12 Hidechika Okada Glycoprotein and gene coding therefor
US4935494A (en) * 1988-11-15 1990-06-19 City Of Hope C-terminal peptide and protein sequencing

Also Published As

Publication number Publication date
CA2014948A1 (en) 1990-10-21
EP0394035B1 (en) 1996-01-10
DE69024693D1 (de) 1996-02-22
EP0672683A1 (en) 1995-09-20
KR900016465A (ko) 1990-11-13
EP0672683B1 (en) 2001-06-27
DE69033756T2 (de) 2002-04-18
IE901426L (en) 1990-10-21
IE960874L (en) 1990-10-21
JP2828148B2 (ja) 1998-11-25
EP0394035A2 (en) 1990-10-24
ATE202570T1 (de) 2001-07-15
EP0394035A3 (en) 1991-08-21
CA2014948C (en) 2000-12-12
US5532339A (en) 1996-07-02
KR0150000B1 (ko) 1998-08-17
GR3019347T3 (en) 1996-06-30
JPH03201985A (ja) 1991-09-03
IE74168B1 (en) 1997-07-02
AU5372690A (en) 1990-11-08
AU640643B2 (en) 1993-09-02
ES2084658T3 (es) 1996-05-16
DE69033756D1 (de) 2001-08-02
DE69024693T2 (de) 1996-07-11
ATE132900T1 (de) 1996-01-15

Similar Documents

Publication Publication Date Title
DK217889D0 (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase
DE68912268T2 (de) Elastomere polypeptide als vaskulare prothesematerialien.
DE3880139T2 (de) Polypeptide mit fibronektinbindender aktivität.
DE3686397T2 (de) Kovalent gebundene polypeptid enthaltende zellmodulatoren.
DE69833667D1 (de) Polynukleotid kodierend für ein polypeptid mit heparanase-aktivität und dessen expression in transduzierten zellen
DE68906293D1 (de) Zufuhr von kohlendioxid.
DE3888921T2 (de) Polypeptide.
DK0394035T3 (da) Gener, der koder for et protein med human MACIF-aktivitet, ekspressionsvektorer indeholdende disse gener, transformantceller og proteiner med human MACIF-aktivitet
NO910982D0 (no) Uratoksydase-aktivt protein, rekombinant gen som koder for det, ekspresjonsvektor, mikroorganismer og transformerteceller.
DE68908633T2 (de) Polypeptide mit zellenverstreuender Aktivität.
GB8901892D0 (en) Nucloetide sequence encoding plant ribosome inactivating protein
DK224985D0 (da) Peptider, og midler indeholdende peptiderne
DK306990D0 (da) Vektor indeholden dna, der koder for human monoaminoxidase type a samt bakterieceller transformeret med en saadan vektor
DK606088D0 (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase
IL92938A0 (en) Polypeptide having human monocyte chemotactic factor activity and dna encoding it
DK502988D0 (da) Polypeptider med interferon- eller interferon-gamma-lignende aktivitet, fremgangsmaade til fremstilling deraf, vektorer, der koder disse polypeptider og farmaceutiske praeparater indeholdende saadanne
DE3882611T2 (de) Menschliches Interleukin-4, Expressionsvektoren dafür und diese enthaltende Transformanten.
DE3886517T2 (de) Menschlicher Prourokinase ähnliches Polypeptid.
DK400786A (da) Udtrykkelsesvektorer til anvendelse i e. coli
NO890174D0 (no) Rekombinante interleukin-1alfa-polypeptider.
NO961086D0 (no) Nye proteiner/polypeptider og kotransfeksjonsplasmider og levende rekombinante bærere for disse
DK130290D0 (da) Lymfokiner, dna-sekvenser, som koder for disse lymfokiner og farmaceutiske midler indeholdende disse lymfokiner
NO178704C (no) DNA-sekvens som koder for protein med IRF-1-aktivitet, ekspresjonsvektor inneholdende denne, anvendelse av IRF-1 for å öke ekspresjon, vertscelle transformert med ekspresjonsvektoren, og protein med IRF-1-aktivitet
ATE92110T1 (de) Menschliches interleukin-4, expressionsvektoren dafuer und diese enthaltende transformanten.
ATE98990T1 (de) Menschlicher prourokinase aehnliches polypeptid.