DE9413599U1 - Agent for topical skin treatment - Google Patents
Agent for topical skin treatmentInfo
- Publication number
- DE9413599U1 DE9413599U1 DE9413599U DE9413599U DE9413599U1 DE 9413599 U1 DE9413599 U1 DE 9413599U1 DE 9413599 U DE9413599 U DE 9413599U DE 9413599 U DE9413599 U DE 9413599U DE 9413599 U1 DE9413599 U1 DE 9413599U1
- Authority
- DE
- Germany
- Prior art keywords
- weight
- total composition
- skin treatment
- agent according
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
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- A—HUMAN NECESSITIES
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- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/9783—Angiosperms [Magnoliophyta]
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Description
A-18/94(j Mittel zur topischen Hautbehandlung A-18/94(j Topical skin treatment products
Die vorliegende Erfindung betrifft ein Mittel zur topischen Hautbehandlung, das der Hautalterung, insbesondere der Faltenbildung, entgegenwirkt.The present invention relates to a topical skin treatment agent that counteracts skin aging, in particular the formation of wrinkles.
Hautbehandlungsmittel, die diese Zielsetzung aufweisen, sind bereits seit Jahrzehnten bekannt. Für diesen Zweck wurden die verschiedensten Substanzen und deren Kombinationen vorgeschlagen. Auch Pflanzenextrakte nehmen dabei einen breiten Raum ein.Skin treatment products that have this objective have been known for decades. A wide variety of substances and their combinations have been proposed for this purpose. Plant extracts also play a large role.
Auch Ginkgo-Extrakt ist zum Einsatz in Hautpflegemitteln bereits vorgeschlagen worden, allein oder im Gemisch mit anderen Wirkstoffen, beispielsweise Polyphenol-Derivaten, wie in der WO-A 94/14414 beschrieben.Ginkgo extract has also been proposed for use in skin care products, alone or in a mixture with other active ingredients, for example polyphenol derivatives, as described in WO-A 94/14414.
Alle diese Zusammensetzungen haben jedoch nicht vermocht, die Aufgabe, die Alterung der Haut, insbesondere die Verminderung des Auftretens von Hautfalten, wirksam zu bekämpfen, zu lösen. Es bestand daher ein Bedürfnis, ein derartiges Mittel zur Verfügung zu stellen.However, all these compositions have not been able to effectively solve the problem of combating skin aging, in particular reducing the appearance of wrinkles. There was therefore a need to make such a remedy available.
Erfindungsgemäß wurde nunmehr festgestellt, daß eine Kombination aus Ginkgo-Extrakt und Glycin geeignet ist, diese Aufgabe in befriedigender Weise zu lösen.According to the invention, it has now been found that a combination of ginkgo extract and glycine is suitable for solving this problem in a satisfactory manner.
Gegenstand der Erfindung ist demgemäß ein Mittel zur topischen Hautbehandlung, das dadurch gekennzeichnet ist, daß es in einem geeigneten Trägermaterial eine Kombination aus einem Ginkgo-Extrakt und Glycin enthält.The invention accordingly relates to an agent for topical skin treatment, which is characterized in that it contains a combination of a ginkgo extract and glycine in a suitable carrier material.
Bei dem erfindungsgemäß eingesetzten Ginkgo-Extrakt handelt es sich vorzugsweise um einen solchen, der durch Extraktion von Ginkgo-Blättern, insbesondere Ginkgo biloba, mit Lösungsmitteln, beispielsweise einem Wasser/Propylenglykol- bzw. 1,3-Butylenglykol-Gemisch, gewonnen wird.The ginkgo extract used according to the invention is preferably one that is obtained by extracting ginkgo leaves, in particular ginkgo biloba, with solvents, for example a water/propylene glycol or 1,3-butylene glycol mixture.
Geeignete Ginkgo-Extrakte sind literaturbekannt, beispielsweise auch aus der erwähnten WO-A 94/14414, und im Handel erhältlich, beispielsweise von der Firma Cosmetochem GmbH unter dem Namen "Herbasol® Extract Ginkgo", oder auch, in konzentrierter Form, der "Flavonoid Complex SC" des gleichen Unternehmens.Suitable ginkgo extracts are known from the literature, for example from the aforementioned WO-A 94/14414, and are commercially available, for example from the company Cosmetochem GmbH under the name "Herbasol® Extract Ginkgo", or also, in concentrated form, the "Flavonoid Complex SC" from the same company.
Der Anteil an Ginkgo-Extrakt in den erfindungsgemäßen Zusammensetzungen ist selbstverständlich von dessen Konzentrationsgrad abhängig und daher über weite Bereiche variabel, er liegt zweckmäßigerweise bei etwa 0,01 bis etwa 5 Gew.-%, vorzugsweise etwa 0,05 bis etwa 2,5 Gew.-% der Gesamtzusammensetzung, wobei von einem Trockenrückstand von etwa 2 bis etwa 15, insbesondere von 3 bis etwa 12 ausgegangen werden kann. Die wirksamen Bestandteile des Ginkgo-Extrakts sind dabei mutmaßlich die darin enthaltenen Flavonoide.The proportion of ginkgo extract in the compositions according to the invention is of course dependent on its concentration level and therefore varies over a wide range; it is suitably about 0.01 to about 5% by weight, preferably about 0.05 to about 2.5% by weight of the total composition, whereby a dry residue of about 2 to about 15, in particular from 3 to about 12, can be assumed. The active components of the ginkgo extract are presumably the flavonoids it contains.
Der zweite essentielle Bestandteil der erfindungsgemäßen Kombination ist Glycin7 vorzugsweise ebenfalls in einer Menge von etwa 0,01 bis 5 Gew.-%, insbesondere 0,05 bis 2,5 Gew.-%, vorzugsweise bis zu etwa 1 Gew.-% der Gesamtzusammensetzung.The second essential component of the combination according to the invention is glycine 7 , preferably also in an amount of about 0.01 to 5% by weight, in particular 0.05 to 2.5% by weight, preferably up to about 1% by weight of the total composition.
Die erfindungsgemäßen Hautbehandlungsmittel können, neben den beiden essentiellen Bestandteilen Ginkgo-Extrakt und Glycin, noch weitere in solchen Mitteln an sich bekannte Wirkstoffe enthalten.The skin treatment agents according to the invention can, in addition to the two essential components ginkgo extract and glycine, also contain other active ingredients known per se in such agents.
Als solche seien insbesondere ölhaltige Nanosomen, vorzugsweise in einer Menge von etwa 0,1 bis etwa 5 Gew.-%, insbesondere 0,25 bis etwa 2,5 Gew.-%, berechnet auf die Gesamtzusammensetzung, genannt. Diese Nanosomen bzw. Nanopartikel bestehen aus einer Hülle aus Lipiden, beispielsweise Sphingolipiden, Phospholipiden oder Ceramiden, und weisen, wie ihr Name bereits andeutet, Teilchengrößen im Nanometerbereich, insbesondere zwischen etwa 50 und etwa 600 nm, vorzugsweise zwischen etwa 100 und 300 nm, auf. Die Lipidphase beträgt dabei etwa 5 bis 35, vorzugsweise 10 bis 30 %, der Anteil an Phospholipiden, insbesondere Lecithin, liegt zwischen etwa 2 und 15, vorzugsweise 5 bis 10 %.Oil-containing nanosomes are particularly mentioned as such, preferably in an amount of about 0.1 to about 5% by weight, in particular 0.25 to about 2.5% by weight, calculated on the total composition. These nanosomes or nanoparticles consist of a shell of lipids, for example sphingolipids, phospholipids or ceramides, and, as their name suggests, have particle sizes in the nanometer range, in particular between about 50 and about 600 nm, preferably between about 100 and 300 nm. The lipid phase is about 5 to 35, preferably 10 to 30%, the proportion of phospholipids, in particular lecithin, is between about 2 and 15, preferably 5 to 10%.
Eine Gruppe von Nanosomen, die sich zum erfindungsgemäßen Einsatz besonders eignen, sind unter der Bezeichnung "Ultraspheres" von der Firma Lipoid KG im Handel; es wird hierzu auch auf die Übersicht von R.A.Brunke und E.Charlet in "Seifen, Öle, Fette, Wachse", Band 117 (1991), S. 514 bis 517, sowie die eigene DE-C 43 02 132 verwiesen.A group of nanosomes that are particularly suitable for use according to the invention are sold under the name "Ultraspheres" by the company Lipoid KG; reference is also made to the overview by R.A. Brunke and E. Charlet in "Seifen, Öle, Fette, Wachse", Volume 117 (1991), pp. 514 to 517, as well as the company's own DE-C 43 02 132.
I · ♦ ·I · ♦ ·
Ein weiterer bevorzugter Bestandteil der erfindungsgemäßen Hautbehandlungsinittel sind Mono-, Di- oder Trihydroxycarbonsäuren bzw. deren wasserlösliche Salze, vorzugsweise in einer Menge von etwa 0,05 bis 5 Gew.-%, insbesondere 0,1 bis 2,5 Gew.-%, bevorzugt 0,25 bis 1 Gew.-%, berechnet auf die Gesamtzusammensetzung des Mittels.Another preferred component of the skin treatment agents according to the invention are mono-, di- or trihydroxycarboxylic acids or their water-soluble salts, preferably in an amount of about 0.05 to 5% by weight, in particular 0.1 to 2.5% by weight, preferably 0.25 to 1% by weight, calculated on the total composition of the agent.
Solche Carbonsäuren sind beispielsweise Milchsäure, Glykolsäure, Äpfelsäure, Weinsäure, Mandelsäure, Citronensäure, o.a. Fruchtsäuren.Such carboxylic acids are, for example, lactic acid, glycolic acid, malic acid, tartaric acid, mandelic acid, citric acid, and other fruit acids.
Diese Hydroxycarbonsäuren, insbesondere die a-Hydroxycarbonsäuren, können auch in an sich bekannter Weise mit Makromolekülen wie Polysacchariden oder Proteinen verbunden sein; entsprechende Produkte sind beispielsweise unter den Namen "Glycacid®" und "Protacid®" im Handel.These hydroxycarboxylic acids, in particular the a-hydroxycarboxylic acids, can also be linked in a known manner to macromolecules such as polysaccharides or proteins; corresponding products are sold, for example, under the names "Glycacid®" and "Protacid®".
Geeignete Polysaccharide sind hierbei beispielsweise Algenextrakt, Chondroitinsulfat, Laminarin, Inulin oder Xanthan, die mit Weinsäure und/oder Äpfelsäure verknüpft sind.Suitable polysaccharides include algae extract, chondroitin sulfate, laminarin, inulin or xanthan, which are linked to tartaric acid and/or malic acid.
Geeignete Proteine sind beispielsweise Casein, Lactalbumin, Seidenprotein, Mandelprotein, Haferprotein, Weizenprotein, Kornprotein, Erbsenprotein oder Sojaprotein, die mit Apfelsäure, Weinsäure und/oder Citronensäure verknüpft sind. Ein besonders bevorzugtes Protein ist ein Soja-/Maisprotein-Reaktionsprodukt mit Apfelsäure.Suitable proteins include casein, lactalbumin, silk protein, almond protein, oat protein, wheat protein, grain protein, pea protein or soy protein linked to malic acid, tartaric acid and/or citric acid. A particularly preferred protein is a soy/corn protein reaction product with malic acid.
Ein weiterer bevorzugt im Rahmen der erfindungsgeinäßen Zusammensetzungen mitverwendeter Bestandteil ist Panthenol, vorzugsweise in einer Menge von 0,05 bis 2,5, insbesondere 0,1 bis 1 Gew.-% der Gesamtzusammensetzung.Another component preferably used in the compositions according to the invention is panthenol, preferably in an amount of 0.05 to 2.5, in particular 0.1 to 1% by weight of the total composition.
Die erfindungsgemäßen Hautbehandlungsmittel können, neben den genannten essentiellen und bevorzugt mitverwendeten Bestandteilen, selbstverständlich weitere in solchen Mitteln übliche wirk- und Hilfsstoffe enthalten. Zur Vermeidung von Wiederholungen wird hierzu auf die Monographie von K.Schrader, "Grundlagen und Rezepturen der Kosmetika", 2. Aufl. (1989, Hüthig Buchverlag, Heidelberg), S. 387 bis 534, hingewiesen, wo im Rahmen zahlreicher Rezepturen sowohl die verschiedensten Wirk- und Hilfsstoffe als auch die für Hautbehandlungsmittel zum Einsatz gelangenden Grundlagen beschrieben sind. Solche sind insbesondere wäßrige und wäßrig-alkoholische Lösungen, wasserin-öl- und Öl-in-Wasser-Emulsionen und Mischformen zwischen beiden sowie Mikroemulsionen, Gele, etc.The skin treatment agents according to the invention can, in addition to the essential and preferably used components mentioned, of course contain other active ingredients and auxiliary substances that are usually used in such agents. To avoid repetition, reference is made to the monograph by K. Schrader, "Grundlagen und Rezepturen der Kosmetika", 2nd edition (1989, Hüthig Buchverlag, Heidelberg), pp. 387 to 534, where, in the context of numerous recipes, the most diverse active ingredients and auxiliary substances as well as the bases used for skin treatment agents are described. These are in particular aqueous and aqueous-alcoholic solutions, water-in-oil and oil-in-water emulsions and mixed forms between the two, as well as microemulsions, gels, etc.
Auch eine Konfektionierung als Schaumaerosol ist erwünschtenfalls möglich.Packaging as a foam aerosol is also possible if desired.
Die Erfindung wird in den folgenden Ausführungsbeispielen näher illustriert und die Wirksamkeit der erfindungsgemäßen Hautbehandlungsmittel nachgewiesen,The invention is illustrated in more detail in the following examples and the effectiveness of the skin treatment agents according to the invention is demonstrated.
Beispiel 1example 1
Verdickte LösungThickened solution
Glycin 0,05 (Gew.-%)Glycine 0.05 (wt%)
Ginkgo-Extract 2,00 (Herbasol® Extract Ginkgo)Ginkgo Extract 2.00 (Herbasol® Extract Ginkgo)
Nanosomen 1,00Nanosomes 1.00
{ültraspheres, enthaltend 20%
Macadamia-Nußöl){ultraspheres, containing 20%
Macadamia nut oil)
Carboxymethylchitin 2,00Carboxymethylchitin 2.00
Panthenol 0,20Panthenol 0.20
Milchsäure O745Lactic acid O 7 45
Natriumlactat 1,50Sodium Lactate 1.50
Polyglycerylmethacrylat 0,75Polyglyceryl methacrylate 0.75
Dimethicone Copolyol 6,00Dimethicone Copolyol 6.00
Lecithin 1,00Lecithin 1.00
Glycerin 20,00Glycerine 20.00
1,3-Butandiol 2,001,3-Butanediol 2.00
Parabene/Phenoxyethanol 0,40 {Konservierungsmittel)Parabens/Phenoxyethanol 0.40 {Preservatives)
Polysorbate 60 0,50Polysorbates 60 0.50
Xanthan Gum 0,50Xanthan Gum 0.50
Dyestuff, UV-Absorber q. s.Dyestuff, UV absorber q. s.
Wasser § 100,00Water § 100.00
■ &tgr;■ &tgr;
Diese Zusammensetzung gemäß Beispiel 1 wurde in einem in vitro-Vergleichsversuch auf ihre Hydroxyl-Radikalfängerwirkung, die ein Maß für die hautschützende Fähigkeit einer Zusammensetzung darstellt (vgl. hierzu E. Mignini et al., "International Journal of Cosmetic Science" ]&Lgr;(1989), S. 21 - 26; D.Friese et al., "Parfümerie und Kosmetik" 72(1991), S. 569 - 574; und B. Levrat, »Seifen, öle, Fette, Wachse" (1992), S. 148 - 155) im System Hyaluronsäure/Xanthin/Xanthinoxidase mit einer ansonsten identischen Vergleichszusammensetzung, die keinen Ginkgo-Extrakt enthielt, verglichen.This composition according to Example 1 was compared in an in vitro comparative test for its hydroxyl radical scavenging effect, which is a measure of the skin-protecting ability of a composition (cf. E. Mignini et al., "International Journal of Cosmetic Science"]�Lgr;(1989), pp. 21 - 26; D.Friese et al., "Parfümerie und Kosmetik" 72(1991), pp. 569 - 574; and B. Levrat, "Seifen, öle, Fette, Wachse" (1992), pp. 148 - 155) in the hyaluronic acid/xanthine/xanthine oxidase system with an otherwise identical comparative composition that did not contain any ginkgo extract.
Ergebnis:Result:
Beispiel 1Composition according to
example 1
setzungComparison summary
setting
Dies zeigt den besonders bei längerer Einwirkung überlegenen Effekt der erfindungsgemäßen, Ginkgo-Extrakt enthaltenden Zusammensetzung.This shows the superior effect of the composition according to the invention containing ginkgo extract, especially after prolonged exposure.
Der in Beispiel 1 beschriebenen Zusammensetzung wurden, unter entsprechender Herabsetzung des Wassergehaltes, noch 2 Gew.-% eines Soja-/Maisprotein-Äpfelsäure(22 : 78)-Kondensats zugesetzt, wodurch insbesondere ein zusätzlicher hautreinigender Effekt erreicht wird.2% by weight of a soy/corn protein-malic acid (22:78) condensate was added to the composition described in Example 1, with a corresponding reduction in the water content, whereby an additional skin-cleansing effect was achieved.
* · * * &Aacgr; *· ·
* · * * &Aacgr;
I · · ·
·· • * *
I · · ·
··
• · »*• · »*
* » « ·#··#··* » « ·#··#··
·« ·· *·« ·· *
(Herbasol® Extract Ginkgo)Ginkgo extract
(Herbasol® Extract Ginkgo)
(Ultraspheres)Nanosomes
(Ultraspheres)
(22 : 78)-KondensatSoy/corn protein-malic acid
(22 : 78) condensate
i St. is .
Beispiel 4Example 4
Öl-in-Wasser-EmulsionOil-in-water emulsion
Ginkgo-Extrakt 2,50 (Gew.-%) (Herbasol® Extract Ginkgo)Ginkgo extract 2.50 (wt.%) (Herbasol® Extract Ginkgo)
Glycin 0,25Glycine 0.25
Panthenol 0,25Panthenol 0.25
Nano somen 1,00 (Ultraspheres, enthaltend 20 %
Macadamia-Nußö1)Nano somen 1.00 (Ultraspheres, containing 20 %
Macadamia nut oil1)
Lecithin 1/00Lecithin 1/00
Capryltriglycerid 8,00Caprylic triglyceride 8.00
Konservierungsmittel 0,70Preservative 0.70
Bienenwachs 1,50Beeswax 1,50
Petrolatum 3,00Petrolatum 3.00
Hydriertes Polyisobuten 2,00Hydrogenated polyisobutene 2.00
Soja-/Maisprotein-Äpfelsäure 1,00 (22 : 78)-KondensatSoy/corn protein malic acid 1.00 (22 : 78) condensate
Dimethicone 0,50Dimethicone 0.50
Mineralöl 6,00Mineral oil 6.00
Cetylstearylalkohol 2,00Cetylstearyl alcohol 2.00
Polysorbate 60 1,00Polysorbates 60 1.00
Glycerylstearat 6,00Glyceryl stearate 6.00
1,2-Propylenglykol 2,001,2-Propylene glycol 2.00
Glycerin 2,50Glycerine 2.50
Parfumöl g.s. Wasser § 100,00Perfume oil g.s. water § 100,00
&Agr;-18^94 10α-18^94 10
(Herbasol® Extract Ginkgo)Ginkgo extract
(Herbasol® Extract Ginkgo)
(Ultraspheres, enthaltend 20 %
Macadaraia-Nußöl)Nanosomes
(Ultraspheres, containing 20 %
Macadamia nut oil)
KondensatMalic acid-soy/corn protein-
condensate
···■*«· · » »
* · · * · · · · · · · ·
···■*«· · » »
* · · * · ·
Claims (7)
Reaktionsprodukte mit Proteinen und/oder Polysacchariden enthält.Mono-, di- or trihydroxycarboxylic acids in the form of their
contains reaction products with proteins and/or polysaccharides.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE9413599U DE9413599U1 (en) | 1994-08-24 | 1994-08-24 | Agent for topical skin treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE9413599U DE9413599U1 (en) | 1994-08-24 | 1994-08-24 | Agent for topical skin treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE9413599U1 true DE9413599U1 (en) | 1995-12-21 |
Family
ID=6912744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE9413599U Expired - Lifetime DE9413599U1 (en) | 1994-08-24 | 1994-08-24 | Agent for topical skin treatment |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE9413599U1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2755012A1 (en) * | 1996-10-31 | 1998-04-30 | Slow Age Creations | Cosmetic compositions to reduce pre-menstrual mammary tension |
-
1994
- 1994-08-24 DE DE9413599U patent/DE9413599U1/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2755012A1 (en) * | 1996-10-31 | 1998-04-30 | Slow Age Creations | Cosmetic compositions to reduce pre-menstrual mammary tension |
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