DE940370C - Process for the production of ointment-like preparations - Google Patents

Process for the production of ointment-like preparations

Info

Publication number
DE940370C
DE940370C DEK3786D DEK0003786D DE940370C DE 940370 C DE940370 C DE 940370C DE K3786 D DEK3786 D DE K3786D DE K0003786 D DEK0003786 D DE K0003786D DE 940370 C DE940370 C DE 940370C
Authority
DE
Germany
Prior art keywords
preparations
ointment
formamide
parts
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEK3786D
Other languages
German (de)
Inventor
Hans P Dr Kaufmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DEK3786D priority Critical patent/DE940370C/en
Application granted granted Critical
Publication of DE940370C publication Critical patent/DE940370C/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)

Description

Verfahren zur Herstellung von salbenartigen Zubereitungen Zusatz zum Patent 937 971 Im Patent 937 97I wird ein Verfahren zur Herstellung von Salben oder ähnlichen Zubereitungen beschrieben, bei dem Formamid zur Anwendung kommt. Letzteres zeigt ein besonderes Lösungsvermögen für manche Stoffe und verhindert die Austrocknung von Salben. Als Grundlagen für derartige Zubereitungen sind Stärke, Traganth und anorganische voluminöse Füllstoffe genannt.Process for the production of ointment-like preparations Patent 937,971 In the patent 937 97I a process for the preparation of ointments or Similar preparations are described in which formamide is used. The latter shows a special dissolving power for some substances and prevents dehydration of ointments. The bases for such preparations are starch, tragacanth and called inorganic voluminous fillers.

Es wurde nun gefunden, daß man mit Vorteil auch Zelluloseabkömmlinge, z. B. Zelluloseäther oder Zelluloseglykolsäuren, desgleichen Zelluloseabbauprodukte, wie z. B. Hemizellulose und Formamid benutzen kann. Diese Stoffe liefern zwar auch mit Wasser fettfreie Salbengrundlagen. Diesen fehlen aber die durch das Formamid bedingten Eigenschaften. Sie trocknen leicht aus und erzeugen zudem auf der Haut einen Film, der manche Anwendungsmöglichkeiten ausschließt. Nun tritt, wie festgestellt wurde, eine derartige Quellung der genannten Stoffe auch in Formamid ein. Es entstehen gallertartige, gut schmierfähige Salbengrundlagen. It has now been found that cellulose derivatives, z. B. cellulose ethers or cellulose glycolic acids, as well as cellulose breakdown products, such as B. Hemicellulose and Formamide can use. These substances also deliver fat-free ointment bases with water. However, these are missing from the formamide conditional properties. They dry out easily and also produce on the skin a film that excludes some possible applications. Now occurs as stated such a swelling of the substances mentioned also in formamide. It arise gelatinous, easy-to-lubricate ointment bases.

Auf der Haut trocknen sie, in dünner Schicht eingerieben, ohne Hinterlassung eines Films ein. Lösliche und unlösliche Stoffe lassen sich zu salben-oder pastenartigen Zubereitungen ohne Schwierigkeiten einarbeiten, sofern sie nicht stärker alkalisch reagieren. Andere Salbengrundlagen, z. B. Stärke, Pflanzenschleime usw. können gegebenenfalls gleich- falls verwandt werden. So gewonnene Zubereitungen sind für technische, vorzugsweise aber für pharmazeutische Zwecke gut geeignet.They dry on the skin, rubbed in a thin layer, without leaving anything behind of a movie. Soluble and insoluble substances can be ointment-like or paste-like Incorporate preparations without difficulty, provided they are not more alkaline react. Other ointment bases, e.g. B. starch, plant mucilage, etc. can optionally same- if used. Preparations obtained in this way are for technical, but preferably well suited for pharmaceutical purposes.

Beispiel 1 7 Teile Zelluloseäther werden in go Teilen Formamid unter gelindem Erwärmen angequollen und 5 Teile Sulfur praec. eingerieben. Example 1 7 parts of cellulose ether are added to parts of formamide swollen by gentle heating and 5 parts sulfur praec. rubbed in.

Beispiel 2 5 Teile des Natriumsalzes einer Zelluloseglykolsäure läßt man in Formamid quellen, worauf man IO Teile Zinkoxyd einreibt. Example 2 Leaves 5 parts of the sodium salt of a cellulose glycolic acid swell in formamide, after which 10 parts of zinc oxide are rubbed in.

Beispiel 3 5 Teile Hemizellulose quellen in 95 Teilen Formamid zu einer gallertartigen, durchsichtigen Salbengrundlage, in der man 5 Teile Salicylsäure löst. Example 3 5 parts of hemicellulose swell in 95 parts of formamide a gelatinous, transparent ointment base in which 5 parts of salicylic acid solves.

Claims (1)

PATENTANSPRUCH: Weitere Ausbildung des Verfahrens nach Patent 937 971, dadurch gekennzeichnet, daß man als Grundlage Zellulosederivate oder Zelluloseabbauprodukte benutzt, die in Formamid zur Quellung gebracht werden. PATENT CLAIM: Further development of the process according to patent 937 971, characterized in that cellulose derivatives or cellulose degradation products are used as the basis used, which are made to swell in formamide.
DEK3786D 1942-05-27 1942-05-27 Process for the production of ointment-like preparations Expired DE940370C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEK3786D DE940370C (en) 1942-05-27 1942-05-27 Process for the production of ointment-like preparations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEK3786D DE940370C (en) 1942-05-27 1942-05-27 Process for the production of ointment-like preparations

Publications (1)

Publication Number Publication Date
DE940370C true DE940370C (en) 1956-03-15

Family

ID=7210043

Family Applications (1)

Application Number Title Priority Date Filing Date
DEK3786D Expired DE940370C (en) 1942-05-27 1942-05-27 Process for the production of ointment-like preparations

Country Status (1)

Country Link
DE (1) DE940370C (en)

Similar Documents

Publication Publication Date Title
US2137169A (en) Medicinal dressing material
DE807395C (en) Process for the impregnation of fibers with synthetic, chain-shaped polyamides
DE212017000348U1 (en) Hydroxypropyl guar gum
DE940370C (en) Process for the production of ointment-like preparations
DE1569114A1 (en) Process for the preparation of water-soluble transparent films from dextrin and polyvinyl alcohol
DE872784C (en) Process for improving the crease resistance of textiles made of cellulose
DE332203C (en) Process for the production of cellulose compounds
DE662035C (en) Process for the production of laxatives
DE872812C (en) Soap
DE765403C (en) Process for the production of brandy jellies
DE739944C (en) Wallpaper paste made from swelling starch
DE683568C (en) Process for the production of water-insoluble, alkali-soluble aralkyl derivatives of cellulose, starch and similar carbohydrates
DE521721C (en) Process for the preparation of alkyl cellulose esters
DE479143C (en) Process for improving the properties of cold-swelling calcium halide starch preparations
DE667999C (en) Process for fortifying rubber milk
AT94837B (en) Process for the production of cellulose derivatives.
AT92889B (en) Process for the production of long-lasting, rapidly soluble silver protein preparations.
DE605016C (en) Process for the production of glues from carbohydrates
DE475214C (en) Process for the preparation of alkyl derivatives of cellulose and other carbohydrates
DE493585C (en) Production of new alkali-soluble, water-insoluble cellulose derivatives
DE930954C (en) Process for the production of easily water-soluble cellulose ether in powder form
DE537324C (en) Process for the production of durable aqueous solutions of silver sodium thiosulphate (2 Na S O íñ Ag S O íñ2H O) for therapeutic purposes
DE725658C (en) Process for the production of cellulose ethers, the aqueous solutions of which are resistant to boiling
DE554926C (en) Dry swelling starch preparations
AT117668B (en) Process for making films from viscose.