DE929426C - Process for the preparation of therapeutically valuable aminosalicylic acid derivatives - Google Patents

Process for the preparation of therapeutically valuable aminosalicylic acid derivatives

Info

Publication number
DE929426C
DE929426C DEC7507A DEC0007507A DE929426C DE 929426 C DE929426 C DE 929426C DE C7507 A DEC7507 A DE C7507A DE C0007507 A DEC0007507 A DE C0007507A DE 929426 C DE929426 C DE 929426C
Authority
DE
Germany
Prior art keywords
acid derivatives
preparation
therapeutically valuable
aminosalicylic acid
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEC7507A
Other languages
German (de)
Inventor
Paul Dr Ochwat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cassella Farbwerke Mainkur AG
Original Assignee
Cassella Farbwerke Mainkur AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Farbwerke Mainkur AG filed Critical Cassella Farbwerke Mainkur AG
Priority to DEC7507A priority Critical patent/DE929426C/en
Application granted granted Critical
Publication of DE929426C publication Critical patent/DE929426C/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

Verfahren zur Herstellung therapeutisch wertvoller Aminosalicylsäurederivate Es wurde gefunden, daß man therapeutisch wertvolle Aniinosalicvlsäurederivate erhält, wenn man 2, 3-Dichlornaplithochinon oder seine Derivate mit einer Aniinosalicvlsiitire umsetzt. Die erhaltenen Verbindungen zeichnen sich insbesondere durch tuherctilostatische Wirkung aus. Beispiel In 45o Teilen destilliertem Wasser «-erden 33 Teile 2, 3-dichlor-i, .4-naplitliochiilon-3-sulfonsaures Natrium mit 189 Teilen p-aininosalicvlsaures Natrium bei Zimmertemperatur mehrere Stunden verrührt. Dann wird auf go° erhitzt und die erhaltene Lösung filtriert. Aus dem Filtrat scheidet sich das Kondensationsprodukt beim Erhalten ab. Es wird abfiltriert und mit wenig destilliertem Wasser gewaschen. Zur Reinigung kann es aus destilliertem Wasser umkristallisiert «-erden. Aus den Filtraten können durch Aussahen weitere Mengen gewonnen werden.Process for the preparation of therapeutically valuable aminosalicylic acid derivatives It has been found that therapeutically valuable amino salicylic acid derivatives are obtained, if one has 2, 3-dichloronaplithoquinone or its derivatives with an anionic salt implements. The compounds obtained are particularly notable for their thermostatic properties Effect. Example In 45o parts of distilled water "earths 33 parts of 2, 3-dichloro-i, .4-Naplitliochiilon-3-sulfonic acid sodium with 189 parts of p-aininosalicvlsaures Stirred sodium for several hours at room temperature. Then it is heated to go ° and the resulting solution is filtered. The condensation product separates out of the filtrate when receiving from. It is filtered off and washed with a little distilled water. For cleaning it can be recrystallized from distilled water. From the Filtrates can be obtained by looking at additional quantities.

Getrocknet stellt das Produkt ein tiefdunkelbraunes, in Wasser leichtlösliches Pulver dar.When dried, the product is deep dark brown, easily soluble in water Powder.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung therapeutisch wertvoller Aminosalicylsäurederivate, dadurch gekennzeichnet, daß man 2, 3-Diclilornaplitliochinon oder seine Derivate mit einer Aminosalici-lsäure umsetzt.PATENT CLAIM: Process for the production of therapeutically valuable Aminosalicylic acid derivatives, characterized in that 2, 3-diclilornaplitlioquinone or its derivatives are reacted with an aminosalicic acid.
DEC7507A 1953-05-01 1953-05-01 Process for the preparation of therapeutically valuable aminosalicylic acid derivatives Expired DE929426C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEC7507A DE929426C (en) 1953-05-01 1953-05-01 Process for the preparation of therapeutically valuable aminosalicylic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEC7507A DE929426C (en) 1953-05-01 1953-05-01 Process for the preparation of therapeutically valuable aminosalicylic acid derivatives

Publications (1)

Publication Number Publication Date
DE929426C true DE929426C (en) 1955-06-27

Family

ID=7014145

Family Applications (1)

Application Number Title Priority Date Filing Date
DEC7507A Expired DE929426C (en) 1953-05-01 1953-05-01 Process for the preparation of therapeutically valuable aminosalicylic acid derivatives

Country Status (1)

Country Link
DE (1) DE929426C (en)

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