DE735010C - Process for the production of nitrogen-containing condensation products - Google Patents

Description

Method of manufacture; -of nitrogen-containing condensation products The present invention relates to a method. for the production of nitrogenous Condensation products, which consists in the fact that one hight molecular protein degradation pr oducts which, in a manner known per se, are alkaline, acidic or enzymatic Ways from ° proteins such as glue, casein, gelatin, skin and leather waste are available are, with low molecular weight aliphatic halocarboxylic acids, appropriate Snit co-halocarboxylic acids, implemented in an alkaline medium.

You already have high molecular weight fatty acid chlorides or halo! enfatty acid chlorides reacted with proteins or their derivatives and highly surface-active, soapy, products obtained.

In addition, halogenated hydrocarbons have been condensed with protein bodies. It has also been proposed to use esters and amides of α-halogen fatty acids with protein degradation products to condense u: iid has reached cleaning agents that are also in an acidic medium are stable and retain their surface-active properties there. Main has Halocarboxylic acids and Halagencarbansäurechloride with native protein for the purpose of production converted by antigens for serum therapy, and by treating proteins The swelling and coagulation of protein bodies has been investigated using halocarboxylic acids.

Furthermore, one has to prepare iminodicarboxylic acids from confgurative Purposes already-optically active-aminocarboxylic acids reacted with chloroacetic acid and the resulting iminodicarboxylic acids examined for their optical activity.

It is not evident from all of these procedures that new valuable ones can be obtained Compounds can be obtained if one further carboxyl groups in the protein breakdown products by> combining them with low molecular weight aliphatic halocarboxylic acids, expediently reacted with ou-halocaxboxylic acids, osin alkaline medium. The on this way obtained products are neither surface active nor can they are used as antigens. Rather, it was surprising that through the increase the carboxyl groups, which are known per se as lime-soap-forming groups, substances can be obtained that the formation of poorly soluble metal salts of soaps or soap-like Connections such as B. of 'Türläschrotölen, Fettalkoholsulfonaten u., D .- "1., prevent or dissolve already formed poorly soluble metal salts. example i io parts of casein breakdown products obtained by treating casein with concentrated Hydrochloric acid obtained at boiling temperature are in alkaline solution stirred with 10 parts of f-chloropropionic acid at ordinary temperature, with on it care is taken that the alkalinity is retained until the end of the reaction. the Solution can be used as such. But you can also use one of the usual ones Subject to drying procedures; dry products are obtained in this way, which contain more or less large amounts of ineffective accompanying substances. To dry products to win who are free of this, one can proceed in such a way that one finds the solutions, in which the condensation is carried out, first acidifies the thereby excreted acidic condensation products are separated off, neutralized and then the resulting Subjecting solutions to a drying process. -Example z io parts by hydrolysis Dry antinoic acid mixture obtained from leather waste is mixed with 20 parts of chloroacetic acid stirred in alkaline solution at ordinary temperature, being careful is that the alkalinity is retained until the end of the reaction. The solution can be used as such or a known one. Subjected to drying processes and d <1nn can be used as the dry product.

Claims (1)

KATI: NTAN $ t'IZUCFI: Process for the production of nitrogenous Condensation products, characterized in that higher molecular weight protein degradation products were used with low molecular weight aliphatic halocarboxylic acids, expediently (,) - halocarboxylic acids, in an alkaline medium.