DE69940254D1 - Verfahren zur herstellung von produkte die inaktivierte hefen oder schimmel und aktive antikörper vom typ vhh enthalten - Google Patents

Verfahren zur herstellung von produkte die inaktivierte hefen oder schimmel und aktive antikörper vom typ vhh enthalten

Info

Publication number
DE69940254D1
DE69940254D1 DE69940254T DE69940254T DE69940254D1 DE 69940254 D1 DE69940254 D1 DE 69940254D1 DE 69940254 T DE69940254 T DE 69940254T DE 69940254 T DE69940254 T DE 69940254T DE 69940254 D1 DE69940254 D1 DE 69940254D1
Authority
DE
Germany
Prior art keywords
products
molding
active antibodies
producing products
inactivated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69940254T
Other languages
English (en)
Inventor
Daniel Convents
Leon G J Frenken
Michael Marie Harmsen
Der Linden Richard H J Van
Theodorus C Verrips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BAC IP BV
Original Assignee
BAC IP BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BAC IP BV filed Critical BAC IP BV
Application granted granted Critical
Publication of DE69940254D1 publication Critical patent/DE69940254D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/195Proteins from microorganisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0047Detergents in the form of bars or tablets
    • C11D17/006Detergents in the form of bars or tablets containing mainly surfactants, but no builders, e.g. syndet bar
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole
DE69940254T 1998-03-12 1999-03-12 Verfahren zur herstellung von produkte die inaktivierte hefen oder schimmel und aktive antikörper vom typ vhh enthalten Expired - Lifetime DE69940254D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98104479 1998-03-12
EP99200439A EP0954978B1 (de) 1998-03-12 1999-02-16 Produkten die inaktivierte Hefen oder Schimmel enthalten, die auf ihrer Aussenoberfläche aktive Antikörper haben
PCT/EP1999/001678 WO1999046300A1 (en) 1998-03-12 1999-03-12 Products comprising inactivated yeasts or moulds and active vhh-type antibodies

Publications (1)

Publication Number Publication Date
DE69940254D1 true DE69940254D1 (de) 2009-02-26

Family

ID=26149079

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69940254T Expired - Lifetime DE69940254D1 (de) 1998-03-12 1999-03-12 Verfahren zur herstellung von produkte die inaktivierte hefen oder schimmel und aktive antikörper vom typ vhh enthalten

Country Status (9)

Country Link
US (2) US8951755B1 (de)
EP (2) EP0954978B1 (de)
AT (1) ATE420113T1 (de)
AU (1) AU2729599A (de)
DE (1) DE69940254D1 (de)
DK (1) DK1062245T3 (de)
ES (1) ES2321044T3 (de)
PT (1) PT1062245E (de)
WO (1) WO1999046300A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100434441C (zh) 1999-04-22 2008-11-19 荷兰联合利华有限公司 利用单价抗原-结合蛋白抑制病毒感染
ATE428733T1 (de) 2000-03-14 2009-05-15 Unilever Nv Variabele domänen der schweren kette eines antikörpers gegen menschliche ernährungslipasen und deren verwendungen
CA2429544C (en) 2000-11-17 2010-10-19 University Of Rochester In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
EP1381345B1 (de) * 2001-03-23 2008-07-09 Advanced Bionutrition Corporation Abgabe von mitteln zur krankheitskontrolle in aquakultur unter verwendung von bioaktive proteine enthaltender hefe
CA2457636C (en) 2001-08-10 2012-01-03 Aberdeen University Antigen binding domains
FR2846667B1 (fr) * 2002-11-06 2004-12-31 Pasteur Institut Fragments variables d'anticorps de camelides a chaine unique diriges contre le peptide beta-amyloide 1-42 et leurs applications pour le diagnostic et le traitement des maladies neuroagregatives
US9320792B2 (en) 2002-11-08 2016-04-26 Ablynx N.V. Pulmonary administration of immunoglobulin single variable domains and constructs thereof
EP1900753B1 (de) 2002-11-08 2017-08-09 Ablynx N.V. Verfahren zur Verabreichung therapeutischer Polypeptide und Polypeptide dafür
EP2267032A3 (de) 2002-11-08 2011-11-09 Ablynx N.V. Verfahren zur Verabreichung therapeutischer Polypeptide und Polypeptide dafür
US20060034845A1 (en) 2002-11-08 2006-02-16 Karen Silence Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
WO2005075515A2 (en) * 2004-02-06 2005-08-18 Unilever N.V. Immunoglobulins and method for their modification
KR101151957B1 (ko) 2004-07-22 2012-06-01 로저 킹돈 크레이그 결합 분자
CN102336832A (zh) * 2004-11-25 2012-02-01 荷兰联合利华有限公司 重链和结构域抗体
WO2006121803A1 (en) 2005-05-05 2006-11-16 Sensient Flavors Inc. Production of beta-glucans and mannans
ZA200800978B (en) * 2005-08-19 2009-08-26 Unilever Plc Food products comprising probiotic micro-organisms and antibodies
US8110112B2 (en) * 2007-05-30 2012-02-07 Innova Prep LLC Liquid to liquid biological particle concentrator
MX2011004558A (es) 2008-10-29 2011-06-01 Wyeth Llc Procedimientos para la purificacion de moleculas de union a antigeno de un unico dominio.
MX345226B (es) 2008-10-29 2017-01-20 Ablynx Nv Formulaciones de moleculas de union a antigeno de dominio sencillo.
US10993420B2 (en) 2013-03-15 2021-05-04 Erasmus University Medical Center Production of heavy chain only antibodies in transgenic mammals
BR112017020275A8 (pt) 2015-03-31 2023-01-31 Sorriso Pharmaceuticals Inc Polipeptídeos
CN114466864A (zh) 2019-06-21 2022-05-10 索瑞索制药公司 多肽
MX2021015763A (es) 2019-06-21 2022-04-18 Sorriso Pharmaceuticals Inc Polipeptidos.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4600706A (en) 1983-11-17 1986-07-15 Carter A F Anti-fungal feed compositions containing natamycin
US4877615A (en) 1988-09-23 1989-10-31 Microlife Technics, Inc. Antifungal product
EP0487159A1 (de) 1990-11-23 1992-05-27 Unilever N.V. Für die Transformation von lebensmittelnsicheren Wirtszellen geeigneter Vektor, seine Verwendung für solche Transformationen und Verwendung der transformierten Zellen in Biotransformationsprozessen
US5326561A (en) 1992-12-15 1994-07-05 Cornell Research Foundation, Inc. Antifungal synergistic combination of enzyme fungicide and non-enzymatic fungicide and use thereof
PT682710E (pt) 1993-02-10 2004-03-31 Unilever Nv Processo de isolamento utilizando proteinas imobilizadas com capacidades de ligacao especificas
DK0698097T3 (da) * 1993-04-29 2001-10-08 Unilever Nv Produktion af antistoffer eller (funktionaliserede) fragmenter deraf afledt af Camelidae-immunoglobuliner med tung kæde
AU7123494A (en) * 1993-06-09 1995-01-03 Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno Process for producing fusion proteins comprising scfv fragments by a transformed mould
US6068862A (en) 1993-06-30 2000-05-30 Taiyo Kagaku Co., Ltd. Tea-derived feed additive and animal feed containing the same
US5585098A (en) * 1993-11-23 1996-12-17 Ovimmune, Inc. Oral administration of chicken yolk immunoglobulins to lower somatic cell count in the milk of lactating ruminants
US6165776A (en) * 1994-03-30 2000-12-26 The United States Of America As Represented By The Secretary Of Commerce Selective and differential medium for isolation of Listeria Monocytogenes
CN1127352C (zh) 1994-08-05 2003-11-12 威斯康星校友研究基金会 用于改善饲料效率的肠促胰酶肽抗体
EP0739981A1 (de) * 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable Fragmente von Immunglobulinen-Verwendung zur therapeutischen oder veterinären Zwecken
US6120732A (en) 1997-06-23 2000-09-19 University Of Georgia Research Foundation, Inc. Microbial inactivation by high-pressure throttling
IT1294368B1 (it) 1997-08-29 1999-03-24 Dox Al Italia Spa Microorganismi inattivati contenenti enzimi digestivi, processo per la loro preparazione e loro uso in campo alimentare
US6033705A (en) * 1998-07-08 2000-03-07 Isaacs; Charles E. Method for treating foodstuffs to reduce or prevent microbial activity

Also Published As

Publication number Publication date
EP0954978B1 (de) 2011-11-30
AU2729599A (en) 1999-09-27
US9080157B2 (en) 2015-07-14
US8951755B1 (en) 2015-02-10
EP1062245A1 (de) 2000-12-27
ATE420113T1 (de) 2009-01-15
US20120309054A1 (en) 2012-12-06
WO1999046300A1 (en) 1999-09-16
ES2321044T3 (es) 2009-06-01
PT1062245E (pt) 2009-04-27
DK1062245T3 (da) 2009-02-16
EP0954978A1 (de) 1999-11-10
EP1062245B1 (de) 2009-01-07

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Legal Events

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