DE69939911D1 - Optisch-aktive DNS-Sonde mit Phosphonsäurediester-Verbindung - Google Patents

Optisch-aktive DNS-Sonde mit Phosphonsäurediester-Verbindung

Info

Publication number
DE69939911D1
DE69939911D1 DE69939911T DE69939911T DE69939911D1 DE 69939911 D1 DE69939911 D1 DE 69939911D1 DE 69939911 T DE69939911 T DE 69939911T DE 69939911 T DE69939911 T DE 69939911T DE 69939911 D1 DE69939911 D1 DE 69939911D1
Authority
DE
Germany
Prior art keywords
optically active
dna probe
diester compound
active dna
phosphonic diester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69939911T
Other languages
English (en)
Inventor
Ryuichi Horie
Takahiko Ishiguro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tosoh Corp
Original Assignee
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12329898A external-priority patent/JP4305966B2/ja
Priority claimed from JP10212569A external-priority patent/JP2000044586A/ja
Application filed by Tosoh Corp filed Critical Tosoh Corp
Application granted granted Critical
Publication of DE69939911D1 publication Critical patent/DE69939911D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69939911T 1998-05-06 1999-05-06 Optisch-aktive DNS-Sonde mit Phosphonsäurediester-Verbindung Expired - Lifetime DE69939911D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12329898A JP4305966B2 (ja) 1998-05-06 1998-05-06 光学活性なホスホン酸ジエステル結合を持つｄｎａプローブ
JP10212569A JP2000044586A (ja) 1998-07-28 1998-07-28 トリアルキルシリル基

Publications (1)

Publication Number Publication Date
DE69939911D1 true DE69939911D1 (de) 2008-12-24

Family

ID=26460266

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69939911T Expired - Lifetime DE69939911D1 (de) 1998-05-06 1999-05-06 Optisch-aktive DNS-Sonde mit Phosphonsäurediester-Verbindung
DE69919778T Expired - Lifetime DE69919778T2 (de) 1998-05-06 1999-05-06 Optisch aktive DNS-Sonde mit Phosphonsäurediester-Bindung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69919778T Expired - Lifetime DE69919778T2 (de) 1998-05-06 1999-05-06 Optisch aktive DNS-Sonde mit Phosphonsäurediester-Bindung

Country Status (4)

Country Link
US (1) US6211354B1 (de)
EP (2) EP0959077B1 (de)
DE (2) DE69939911D1 (de)
HK (1) HK1059787A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4438110B2 (ja) * 1998-07-01 2010-03-24 東ソー株式会社 標的核酸の定量方法
EP1035214B1 (de) 1999-03-05 2005-12-21 Tosoh Corporation Eine am 3'-Ende modifizierte Nukleinsäuresonde, geeignet zur Hybridisierung und Detektion über Fluoreszenz
JP2003116543A (ja) * 2001-10-10 2003-04-22 Tosoh Corp 薬効と毒性の評価法
FR3092115B1 (fr) 2019-01-30 2021-11-12 Cisbio Bioassays analogues de GTP fluorescents et utilisation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS614353A (ja) 1984-06-19 1986-01-10 Nec Corp 電話交換機の付帯装置
JPS6144353A (ja) 1984-08-07 1986-03-04 Yuki Gosei Yakuhin Kogyo Kk 蛍光標識化されたポリヌクレオチドとその製法
US5852188A (en) * 1990-01-11 1998-12-22 Isis Pharmaceuticals, Inc. Oligonucleotides having chiral phosphorus linkages
US5212295A (en) * 1990-01-11 1993-05-18 Isis Pharmaceuticals Monomers for preparation of oligonucleotides having chiral phosphorus linkages
NZ239250A (en) 1990-08-09 1993-12-23 Genta Inc Chirally pure non-nucleotide reagents for use in preparing
US5512668A (en) * 1991-03-06 1996-04-30 Polish Academy Of Sciences Solid phase oligonucleotide synthesis using phospholane intermediates
US5359052A (en) * 1991-08-05 1994-10-25 Polish Academy Of Sciences Chalcophospholanes useful in the synthesis of oligonucleoside phosphorothioates, phosphorodithioates and related selenates
US5599796A (en) * 1993-12-02 1997-02-04 Emory University Treatment of urogenital cancer with boron neutron capture therapy
JP3189000B2 (ja) 1994-12-01 2001-07-16 東ソー株式会社 特定核酸配列の検出方法
WO1997009340A1 (en) 1995-09-01 1997-03-13 Polska Akademia Nauk Centrum Badan Molekularnych I Makromolekularnych Compositions and methods for the synthesis of organophosphorus derivatives
US5856465A (en) * 1996-05-24 1999-01-05 Polska Akademia Nauk Centrum Badan Molekularnych I Makromolekularnych Compositions and methods for the synthesis of chirally pure organophosphorus nucleoside derivatives

Also Published As

Publication number Publication date
EP1340766A1 (de) 2003-09-03
HK1059787A1 (en) 2004-07-16
DE69919778D1 (de) 2004-10-07
EP1340766B1 (de) 2008-11-12
DE69919778T2 (de) 2005-09-22
US6211354B1 (en) 2001-04-03
EP0959077A1 (de) 1999-11-24
EP0959077B1 (de) 2004-09-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition