DE69933283D1 - Photoaktivierbare nukleinsäure-derivate - Google Patents
Photoaktivierbare nukleinsäure-derivateInfo
- Publication number
- DE69933283D1 DE69933283D1 DE69933283T DE69933283T DE69933283D1 DE 69933283 D1 DE69933283 D1 DE 69933283D1 DE 69933283 T DE69933283 T DE 69933283T DE 69933283 T DE69933283 T DE 69933283T DE 69933283 D1 DE69933283 D1 DE 69933283D1
- Authority
- DE
- Germany
- Prior art keywords
- photoactivable
- nucleic acid
- acid derivatives
- derivatives
- nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/04—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0047—Enzymes, e.g. urokinase, streptokinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8121—Serpins
- G01N2333/8128—Antithrombin III
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/974—Thrombin
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/028,806 US6506895B2 (en) | 1997-08-15 | 1998-02-24 | Photoactivatable nucleic acids |
PCT/US1999/003862 WO1999043688A1 (en) | 1998-02-24 | 1999-02-23 | Photoactivatable nucleic acid derivatives |
US28806 | 2001-10-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69933283D1 true DE69933283D1 (de) | 2006-11-02 |
DE69933283T2 DE69933283T2 (de) | 2007-04-26 |
Family
ID=21845539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69933283T Expired - Fee Related DE69933283T2 (de) | 1998-02-24 | 1999-02-23 | Photoaktivierbare nukleinsäure-derivate |
Country Status (7)
Country | Link |
---|---|
US (1) | US6506895B2 (de) |
EP (1) | EP1064292B1 (de) |
JP (1) | JP2002504695A (de) |
AU (1) | AU758328B2 (de) |
CA (1) | CA2321098A1 (de) |
DE (1) | DE69933283T2 (de) |
WO (1) | WO1999043688A1 (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL124322A (en) * | 1998-05-04 | 2002-05-23 | Technion Res & Dev Foundation | Detection of an entity in a sample |
US20030096265A1 (en) * | 1999-06-25 | 2003-05-22 | Motorola, Inc. | Phosphoramidites for coupling oligonucleotides to [2 + 2] photoreactive groups |
US6921638B2 (en) | 1999-06-25 | 2005-07-26 | Amersham Biosciences Ab | Hydrogel-based microarray signal amplification methods and devices therefor |
IL147286A0 (en) * | 1999-07-07 | 2002-08-14 | Exiqon As | Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates |
US6531591B1 (en) | 1999-07-07 | 2003-03-11 | Exiqon A/S | Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates |
EP1130121A3 (de) * | 2000-01-26 | 2003-04-16 | Nisshinbo Industries Inc. | Immobilisierte Nukleinsäuren und Methoden zum Nchhweis von Nukleinsäuren |
US20030077636A1 (en) * | 2000-03-31 | 2003-04-24 | Andreas Bosio | Use of particles which have signal-emitting characteristics and at least one group with an affinity for maked nucleic acids |
DE10103954B4 (de) | 2001-01-30 | 2005-10-06 | Advalytix Ag | Verfahren zur Analyse von Makromolekülen |
US7501157B2 (en) | 2001-06-26 | 2009-03-10 | Accelr8 Technology Corporation | Hydroxyl functional surface coating |
US6844028B2 (en) | 2001-06-26 | 2005-01-18 | Accelr8 Technology Corporation | Functional surface coating |
US7297553B2 (en) * | 2002-05-28 | 2007-11-20 | Nanosphere, Inc. | Method for attachment of silylated molecules to glass surfaces |
WO2003006676A2 (en) * | 2001-07-13 | 2003-01-23 | Nanosphere, Inc. | Method for immobilizing molecules onto surfaces |
US6444318B1 (en) | 2001-07-17 | 2002-09-03 | Surmodics, Inc. | Self assembling monolayer compositions |
US7348055B2 (en) | 2001-12-21 | 2008-03-25 | Surmodics, Inc. | Reagent and method for providing coatings on surfaces |
EP1486561B1 (de) * | 2001-12-26 | 2013-12-04 | Canon Kabushiki Kaisha | Sondenmedium |
US7166478B2 (en) * | 2002-03-12 | 2007-01-23 | Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses |
DE10233303A1 (de) * | 2002-07-22 | 2004-02-12 | Micronas Holding Gmbh | Sensoroberfläche mit verbessertem Signal/Rausch-Verhältnis |
DE10237704A1 (de) * | 2002-08-09 | 2004-03-11 | Chemogenix Gmbh | Verfahren und Vorrichtung zum intermolekularen Transfer von Aktivierungsenergie zur Bindungsspaltung durch den Raum |
JP3901120B2 (ja) | 2003-04-09 | 2007-04-04 | 独立行政法人理化学研究所 | 固相担体への低分子化合物の固定方法 |
US20050202447A1 (en) * | 2004-03-11 | 2005-09-15 | Surmodics, Inc. | Array print buffers |
CN1947013A (zh) * | 2004-04-23 | 2007-04-11 | 松下电器产业株式会社 | 基因检测方法和基因检测装置 |
US20070048759A1 (en) * | 2005-06-10 | 2007-03-01 | Dan Luo | Detection of target molecules with labeled nucleic acid detection molecules |
US8486621B2 (en) * | 2005-08-11 | 2013-07-16 | Cornell Research Foundation, Inc. | Nucleic acid-based matrixes |
US20070148246A1 (en) * | 2005-08-11 | 2007-06-28 | Dan Luo | Nucleic Acid-Based Matrixes |
US8277928B2 (en) * | 2005-11-08 | 2012-10-02 | Surmodics, Inc. | Ultra-thin photo-polymer coatings and uses thereof |
WO2008118167A1 (en) * | 2006-03-24 | 2008-10-02 | The Regents Of The University Of Michigan | Method for forming molecular sequences on surfaces |
WO2008056837A1 (en) * | 2006-11-07 | 2008-05-15 | Korea Research Institute Of Bioscience And Biotechnology | Method for fabricating a biomaterial array using photoreaction |
EP2324045A4 (de) * | 2008-08-05 | 2013-04-03 | Univ Cornell | Photovernetzte nukleinsäurehydrogele |
US10058634B2 (en) | 2009-04-28 | 2018-08-28 | Surmodics, Inc. | Devices and methods for delivery of bioactive agents |
US20110105990A1 (en) * | 2009-11-04 | 2011-05-05 | Silvestrini Thomas A | Zonal drug delivery device and method |
US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
US20120258892A1 (en) * | 2011-04-08 | 2012-10-11 | Yan Wang | Methods, Compositions, and Kits for Making Targeted Nucleic Acid Libraries |
US9861727B2 (en) | 2011-05-20 | 2018-01-09 | Surmodics, Inc. | Delivery of hydrophobic active agent particles |
US11246963B2 (en) | 2012-11-05 | 2022-02-15 | Surmodics, Inc. | Compositions and methods for delivery of hydrophobic active agents |
EP3250249B1 (de) * | 2015-01-29 | 2021-12-08 | SurModics, Inc. | Freisetzung von hydrophoben wirkstoffteilchen |
CN105037237B (zh) * | 2015-06-12 | 2017-10-03 | 苏州昊帆生物科技有限公司 | 合成n‑马来酰亚胺基烷基酸及其琥珀酰亚胺酯的方法 |
US10898446B2 (en) | 2016-12-20 | 2021-01-26 | Surmodics, Inc. | Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5512329A (en) | 1982-09-29 | 1996-04-30 | Bsi Corporation | Substrate surface preparation |
US4722906A (en) | 1982-09-29 | 1988-02-02 | Bio-Metric Systems, Inc. | Binding reagents and methods |
US4973493A (en) | 1982-09-29 | 1990-11-27 | Bio-Metric Systems, Inc. | Method of improving the biocompatibility of solid surfaces |
US5217492A (en) | 1982-09-29 | 1993-06-08 | Bio-Metric Systems, Inc. | Biomolecule attachment to hydrophobic surfaces |
US4629623A (en) | 1984-06-11 | 1986-12-16 | Biomatrix, Inc. | Hyaluronate-poly (ethylene oxide) compositions and cosmetic formulations thereof |
US5263992A (en) | 1986-10-17 | 1993-11-23 | Bio-Metric Systems, Inc. | Biocompatible device with covalently bonded biocompatible agent |
US4979959A (en) | 1986-10-17 | 1990-12-25 | Bio-Metric Systems, Inc. | Biocompatible coating for solid surfaces |
FR2655048A1 (fr) | 1989-11-27 | 1991-05-31 | Inst Nat Sante Rech Med | Procede d'obtention de copolymeres bioactifs par greffage de motifs vinyliques et copolymeres greffes resultants. |
WO1991016425A1 (de) * | 1990-04-12 | 1991-10-31 | Hans Sigrist | Verfahren zur lichtinduzierten immobilisierung von biomolekülen an chemisch 'inerten' oberflächen |
ATE244065T1 (de) | 1990-12-06 | 2003-07-15 | Affymetrix Inc | Verfahren und reagenzien für immobilisierten polymersynthese in sehr grossem masstab |
EP0610441A4 (de) | 1991-10-29 | 1996-01-10 | Clover Cons Ltd | Vernetzbare polysacchariden, polykationen und lipiden verwendbar zum einkapseln und abgabe von arzneimitteln. |
ATE192487T1 (de) | 1992-02-13 | 2000-05-15 | Surmodics Inc | Immobilisierung eines chemischen spezies in einer vernetzten matrix |
US5414075A (en) | 1992-11-06 | 1995-05-09 | Bsi Corporation | Restrained multifunctional reagent for surface modification |
CA2154444A1 (en) | 1993-01-21 | 1994-08-04 | John F. W. Keana | Chemical functionalization of surfaces |
US5552199A (en) | 1994-09-02 | 1996-09-03 | Minnesota Mining And Manufacturing Company | Melt-processable electroconductive fluoroplastic |
US5616902A (en) | 1994-09-12 | 1997-04-01 | Lottery Enterprises Inc. | Bill pay system and method |
US5688642A (en) | 1994-12-01 | 1997-11-18 | The United States Of America As Represented By The Secretary Of The Navy | Selective attachment of nucleic acid molecules to patterned self-assembled surfaces |
US5527282A (en) | 1994-12-09 | 1996-06-18 | Segal; Jerome | Vascular dilatation device and method |
DE19518247A1 (de) | 1995-05-18 | 1996-11-21 | Stoess & Co Gelatine | Wasserresistentes Barrierematerial |
US5676597A (en) | 1995-07-27 | 1997-10-14 | Building Materials Corporation Of America | Vented hip, ridge and rake composite shingle |
DE19533682A1 (de) * | 1995-09-12 | 1997-03-13 | Biotronik Mess & Therapieg | Verfahren zum Anlagern und Immobilisieren von Heparin auf anorganischen Substratoberflächen von kardiovaskulären Implantanten |
US5714360A (en) * | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
AU3568897A (en) * | 1996-06-07 | 1998-01-05 | Eos Biotechnology, Inc. | Immobilised linear oligonucleotide arrays |
US5986136A (en) * | 1997-04-15 | 1999-11-16 | President And Fellows Of Harvard College | Photolabeling reagent |
US6121027A (en) * | 1997-08-15 | 2000-09-19 | Surmodics, Inc. | Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups |
-
1998
- 1998-02-24 US US09/028,806 patent/US6506895B2/en not_active Expired - Fee Related
-
1999
- 1999-02-23 EP EP99909547A patent/EP1064292B1/de not_active Expired - Lifetime
- 1999-02-23 CA CA002321098A patent/CA2321098A1/en not_active Abandoned
- 1999-02-23 WO PCT/US1999/003862 patent/WO1999043688A1/en active IP Right Grant
- 1999-02-23 AU AU28729/99A patent/AU758328B2/en not_active Ceased
- 1999-02-23 JP JP2000533440A patent/JP2002504695A/ja active Pending
- 1999-02-23 DE DE69933283T patent/DE69933283T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU758328B2 (en) | 2003-03-20 |
US20020086989A1 (en) | 2002-07-04 |
EP1064292B1 (de) | 2006-09-20 |
CA2321098A1 (en) | 1999-09-02 |
DE69933283T2 (de) | 2007-04-26 |
EP1064292A1 (de) | 2001-01-03 |
US6506895B2 (en) | 2003-01-14 |
WO1999043688A1 (en) | 1999-09-02 |
JP2002504695A (ja) | 2002-02-12 |
AU2872999A (en) | 1999-09-15 |
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