DE69932901D1 - Verfahren zur Isolierung und Rückgewinnung von Zellen - Google Patents
Verfahren zur Isolierung und Rückgewinnung von ZellenInfo
- Publication number
- DE69932901D1 DE69932901D1 DE69932901T DE69932901T DE69932901D1 DE 69932901 D1 DE69932901 D1 DE 69932901D1 DE 69932901 T DE69932901 T DE 69932901T DE 69932901 T DE69932901 T DE 69932901T DE 69932901 D1 DE69932901 D1 DE 69932901D1
- Authority
- DE
- Germany
- Prior art keywords
- filtering device
- isolating
- line
- recovering
- priming liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000001914 filtration Methods 0.000 abstract 6
- 239000007788 liquid Substances 0.000 abstract 4
- 230000037452 priming Effects 0.000 abstract 3
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/12—Composite membranes; Ultra-thin membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0236—Multiple bag systems for separating or storing blood components with sampling means, e.g. sample bag or sampling port
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
- A61M1/3644—Mode of operation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7554—General characteristics of the apparatus with filters with means for unclogging or regenerating filters
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Water Supply & Treatment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27936498 | 1998-09-14 | ||
JP27936498A JP3517359B2 (ja) | 1998-09-14 | 1998-09-14 | 細胞分離・回収装置および細胞の分離・回収方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69932901D1 true DE69932901D1 (de) | 2006-10-05 |
DE69932901T2 DE69932901T2 (de) | 2007-03-01 |
Family
ID=17610139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69932901T Expired - Lifetime DE69932901T2 (de) | 1998-09-14 | 1999-09-13 | Verfahren zur Isolierung und Rückgewinnung von Zellen |
Country Status (5)
Country | Link |
---|---|
US (1) | US6312950B1 (de) |
EP (1) | EP0987034B1 (de) |
JP (1) | JP3517359B2 (de) |
AT (1) | ATE337035T1 (de) |
DE (1) | DE69932901T2 (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306350B1 (en) * | 1999-05-19 | 2001-10-23 | Itt Manufacturing Enterprises, Inc. | Water sampling method and apparatus with analyte integration |
WO2001051170A1 (en) * | 2000-01-14 | 2001-07-19 | Mykrolis Corporation | System and method for liquid filtration based on a neutral filter material |
WO2002005059A2 (en) * | 2000-07-07 | 2002-01-17 | Baxter International Inc. | Medical system, method and apparatus employing mems |
US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
WO2002046373A1 (en) | 2000-12-06 | 2002-06-13 | Hariri Robert J | Method of collecting placental stem cells |
EP2336299A1 (de) * | 2001-02-14 | 2011-06-22 | Anthrogenesis Corporation | Post-partum Säugetier-Plazenta, deren Verwendung und daraus gewonnene Stammzellen |
FR2825261B1 (fr) * | 2001-06-01 | 2003-09-12 | Maco Pharma Sa | Ligne de prelevement du sang placentaire comprenant une poche de rincage |
US6623959B2 (en) | 2001-06-13 | 2003-09-23 | Ethicon, Inc. | Devices and methods for cell harvesting |
US7156803B2 (en) | 2002-08-19 | 2007-01-02 | Depuy Spine, Inc. | Devices for controlling fluid flow through a medium |
EP1571910A4 (de) | 2002-11-26 | 2009-10-28 | Anthrogenesis Corp | Zytotherapeutika, zytotherapeutischeeinheiten und behandlungsverfahren, bei denen diese verwendet werden |
JP4158095B2 (ja) * | 2003-01-15 | 2008-10-01 | 株式会社クニムネ | 尿検体の採取・保存器具 |
US7601268B2 (en) * | 2003-05-27 | 2009-10-13 | Haemonetics Corporation | Continuous blood filtration and method of use |
JP2007017151A (ja) * | 2003-09-30 | 2007-01-25 | Dai Ichi Pure Chem Co Ltd | フィルターホルダーとそれを装着した検査用フィルターユニット |
WO2007047468A2 (en) | 2005-10-13 | 2007-04-26 | Anthrogenesis Corporation | Immunomodulation using placental stem cells |
ZA200804718B (en) | 2005-12-29 | 2010-04-28 | Anthrogenesis Corp | Co-culture of placental stem cells and stem cells from a second source |
NZ595786A (en) | 2005-12-29 | 2013-05-31 | Anthrogenesis Corp | Placental stem cell populations |
EP2630959A1 (de) | 2007-02-12 | 2013-08-28 | Anthrogenesis Corporation | Behandlung von Infektionskrankheiten mithilfe von Plazenta-Stammzellen |
AU2008223632B2 (en) | 2007-03-02 | 2012-11-01 | Smith & Nephew Plc | Apparatus and method for solid/liquid separation by filtration |
US9200253B1 (en) | 2007-08-06 | 2015-12-01 | Anthrogenesis Corporation | Method of producing erythrocytes |
KR20230065354A (ko) | 2007-09-28 | 2023-05-11 | 셀룰래리티 인코포레이티드 | 인간 태반 관류액 및 인간 태반-유래 중간체 천연 킬러 세포를 사용한 종양 억제 방법 |
WO2009122999A1 (ja) | 2008-03-31 | 2009-10-08 | シスメックス株式会社 | 試料調製装置及び試料調製方法、並びに、細胞分析装置及び細胞分析方法 |
JP5003614B2 (ja) * | 2008-07-03 | 2012-08-15 | 株式会社日立プラントテクノロジー | 生体細胞の分離方法及び培養装置 |
PE20110399A1 (es) | 2008-08-20 | 2011-06-22 | Anthrogenesis Corp | Tratamiento de la apoplejia utilizando celulas placentarias aisladas |
CA2734236C (en) | 2008-08-20 | 2020-08-25 | Anthrogenesis Corporation | Improved cell composition and methods of making the same |
NZ591293A (en) | 2008-08-22 | 2012-10-26 | Anthrogenesis Corp | Methods and compositions for treatment of bone defects with osteogenic placental adherent cells (OPACs) |
JP2010094266A (ja) * | 2008-10-16 | 2010-04-30 | Nipro Corp | 体外循環モジュールのプライミング用液体およびプライミング方法 |
NZ602455A (en) | 2008-11-19 | 2014-03-28 | Anthrogenesis Corp | Amnion derived adherent cells |
KR101674517B1 (ko) * | 2009-06-30 | 2016-11-09 | 가부시키가이샤 가네카 | 혈액 성분의 분리 시스템, 분리재 |
AU2010266263B2 (en) | 2009-07-02 | 2016-05-19 | Celularity Inc. | Method of producing erythrocytes without feeder cells |
DE102009052671B4 (de) * | 2009-11-12 | 2015-07-30 | Sartorius Stedim Biotech Gmbh | Vorrichtung und Verfahren zur Behandlung eines Filtrationsmediums |
CA2787992A1 (en) | 2010-01-26 | 2011-08-04 | Anthrogenesis Corporation | Treatment of bone-related cancers using placental stem cells |
JP5826168B2 (ja) * | 2010-03-31 | 2015-12-02 | 旭化成メディカル株式会社 | 白血球除去器のプライミングシステム及びプライミング方法 |
KR20200047797A (ko) | 2010-04-07 | 2020-05-07 | 안트로제네시스 코포레이션 | 태반 줄기 세포를 사용한 혈관신생 |
CN102933221A (zh) | 2010-04-08 | 2013-02-13 | 人类起源公司 | 使用胎盘干细胞治疗结节病 |
KR20230096132A (ko) | 2010-07-13 | 2023-06-29 | 셀룰래리티 인코포레이티드 | 천연 킬러 세포의 생성 방법 |
DE102010047826A1 (de) * | 2010-10-04 | 2012-04-05 | Eppendorf Ag | Elektronische Pipette |
JP2012120457A (ja) * | 2010-12-06 | 2012-06-28 | Kaneka Corp | プライミング装置機能付き細胞分離装置およびそれを用いたプライミング法。 |
JP2012120458A (ja) * | 2010-12-06 | 2012-06-28 | Kaneka Corp | 細胞の分離器具。 |
JP5738582B2 (ja) * | 2010-12-06 | 2015-06-24 | 株式会社カネカ | プライミング時の気泡の除去を簡便にする部材を備えた細胞溶液処理器具およびその使用方法 |
US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
WO2012125463A1 (en) * | 2011-03-11 | 2012-09-20 | Fenwal, Inc. | Membrane separation devices, systems and methods employing same, and data management systems and methods |
ES2707579T3 (es) | 2011-06-01 | 2019-04-04 | Celularity Inc | Tratamiento del dolor usando citoblastos placentarios |
JP2013034436A (ja) * | 2011-08-09 | 2013-02-21 | Kaneka Corp | 細胞懸濁液の濃縮方法 |
DE102011112291B4 (de) * | 2011-09-05 | 2015-07-09 | Sartorius Stedim Biotech Gmbh | Vorrichtung und Verfahren zur Filtration einer Flüssigkeitsprobe |
US9925221B2 (en) | 2011-09-09 | 2018-03-27 | Celularity, Inc. | Treatment of amyotrophic lateral sclerosis using placental stem cells |
WO2013102165A2 (en) * | 2011-12-29 | 2013-07-04 | Delcath Systems, Inc. | Adjustable filter apparatus |
US10105622B2 (en) | 2012-05-30 | 2018-10-23 | Ge Healthcare Bio-Sciences Ab | Filtration cassette and a stack of filtration cassettes |
US9066909B2 (en) | 2012-09-06 | 2015-06-30 | Biomet Biologics, Llc | Methods for producing and using rejuvenated red blood cells |
US10253295B2 (en) | 2012-09-06 | 2019-04-09 | Biomet Manufacturing, Llc | Methods for producing rejuvenated red blood cells |
JP6113988B2 (ja) * | 2012-09-26 | 2017-04-12 | 旭化成株式会社 | 腹水処理システム及び複合システム |
US9102918B2 (en) | 2013-01-31 | 2015-08-11 | Biomet Biologics, Llc | Methods for rejuvenating red blood cells |
US9011408B2 (en) | 2013-01-31 | 2015-04-21 | Biomet Biologics, Llc | Functionally-closed, sterile blood processing solution system and method |
US9103842B2 (en) | 2013-01-31 | 2015-08-11 | Biomet Biologics, Llc | Methods for rejuvenating red blood cells |
EP3622960A1 (de) | 2013-02-05 | 2020-03-18 | Celularity, Inc. | Natürliche killerzellen aus plazenta |
JP6251998B2 (ja) * | 2013-07-05 | 2017-12-27 | 日立化成株式会社 | 細胞捕捉システム及び細胞捕捉システムの運転方法 |
JP6299115B2 (ja) * | 2013-08-29 | 2018-03-28 | 日立化成株式会社 | 細胞捕捉デバイス及び細胞捕捉システム |
US10676707B2 (en) | 2013-09-12 | 2020-06-09 | Universal Bio Research Co., Ltd. | Culture system and culture method |
EP3045520A4 (de) * | 2013-09-13 | 2017-04-26 | Medinet Co., Ltd. | Filtrationsinstrument für eine zellsuspension und verfahren zur herstellung einer tropfinfusionslösung mit der zellsuspension |
US9067172B1 (en) * | 2014-01-28 | 2015-06-30 | Air Products And Chemicals, Inc. | Solid-state membrane module |
US20150209721A1 (en) * | 2014-01-28 | 2015-07-30 | Air Products And Chemicals, Inc. | Solid-State Membrane Module |
WO2016056512A1 (ja) * | 2014-10-08 | 2016-04-14 | 日立化成株式会社 | 細胞捕捉デバイス |
KR101776245B1 (ko) * | 2014-11-20 | 2017-09-11 | 울산과학기술원 | 입자 여과 장치 및 입자 여과 방법 |
JP6615577B2 (ja) * | 2015-10-29 | 2019-12-04 | 株式会社カネカ | 細胞分離フィルターを用いた細胞濃縮液の製造方法 |
CN114712698A (zh) * | 2016-06-16 | 2022-07-08 | 美国血液技术公司 | 用于血液处理系统的管道装置和连接器 |
DE102018004521A1 (de) * | 2018-06-07 | 2019-12-12 | Sartorius Stedim Biotech Gmbh | Serielle Anordnung mit mehreren Lagen asymmetrischer Filtermedien, Herstellungsverfahren, Filtrationseinheit, Verwendung der Anordnung und Charakterisierungsverfahren |
US11320345B2 (en) * | 2019-03-18 | 2022-05-03 | Avantor Fluid Handling, Llc | Adjustable volume sampling system (AVSS) |
CN110511860B (zh) * | 2019-09-06 | 2022-09-06 | 辽宁鼎天生命科技有限公司 | 一种用于实验室提取干细胞的一体化装置 |
DE102019215029A1 (de) * | 2019-09-30 | 2021-04-01 | Robert Bosch Gmbh | Filterabfolge, Spritzenaufsatz und Verfahren zur Separierung von Partikeln aus einer Körperflüssigkeit |
DE102020216578B4 (de) * | 2020-12-28 | 2023-02-09 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein | Vorrichtung und Verfahren zur Separation von unterschiedlich großen Partikeln in einer Flüssigkeit und Verwendungen der Vorrichtung |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1329559C (en) * | 1988-03-03 | 1994-05-17 | Keiji Naoi | Leukocyte separator and method of making the same |
JP3322595B2 (ja) * | 1996-03-28 | 2002-09-09 | テルモ株式会社 | フィルター装置および生体微細組織の分離・回収方法 |
US6120474A (en) * | 1997-12-15 | 2000-09-19 | Nissho Corporation | Blood component-recovering apparatus and a method for recovering blood components using the same |
-
1998
- 1998-09-14 JP JP27936498A patent/JP3517359B2/ja not_active Expired - Lifetime
-
1999
- 1999-09-13 AT AT99118189T patent/ATE337035T1/de not_active IP Right Cessation
- 1999-09-13 EP EP99118189A patent/EP0987034B1/de not_active Expired - Lifetime
- 1999-09-13 DE DE69932901T patent/DE69932901T2/de not_active Expired - Lifetime
- 1999-09-14 US US09/395,740 patent/US6312950B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6312950B1 (en) | 2001-11-06 |
EP0987034B1 (de) | 2006-08-23 |
JP2000083649A (ja) | 2000-03-28 |
EP0987034A3 (de) | 2000-10-04 |
ATE337035T1 (de) | 2006-09-15 |
JP3517359B2 (ja) | 2004-04-12 |
DE69932901T2 (de) | 2007-03-01 |
EP0987034A2 (de) | 2000-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |