DE69930123D1 - Zielgerichtete integration in chromosomen mittels retroviraler vektoren - Google Patents

Zielgerichtete integration in chromosomen mittels retroviraler vektoren

Info

Publication number
DE69930123D1
DE69930123D1 DE69930123T DE69930123T DE69930123D1 DE 69930123 D1 DE69930123 D1 DE 69930123D1 DE 69930123 T DE69930123 T DE 69930123T DE 69930123 T DE69930123 T DE 69930123T DE 69930123 D1 DE69930123 D1 DE 69930123D1
Authority
DE
Germany
Prior art keywords
chromosomes
retroviral vectors
targeted integration
gene therapy
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69930123T
Other languages
English (en)
Other versions
DE69930123T2 (de
Inventor
Walter Guenzburg
Brian Salmons
Sabine Strauss-Goller
Dieter Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Original Assignee
Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut fuer Virologie der Veterinaermedizinische Universitaet Wien filed Critical Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Publication of DE69930123D1 publication Critical patent/DE69930123D1/de
Application granted granted Critical
Publication of DE69930123T2 publication Critical patent/DE69930123T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Complex Calculations (AREA)
  • Feedback Control In General (AREA)
  • Compression Or Coding Systems Of Tv Signals (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69930123T 1998-07-01 1999-06-30 Zielgerichtete integration in chromosomen mittels retroviraler vektoren Expired - Fee Related DE69930123T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199801016 1998-07-01
DK101698 1998-07-01
PCT/EP1999/004521 WO2000001835A2 (en) 1998-07-01 1999-06-30 Targeted integration into chromosomes using retroviral vectors

Publications (2)

Publication Number Publication Date
DE69930123D1 true DE69930123D1 (de) 2006-04-27
DE69930123T2 DE69930123T2 (de) 2006-10-12

Family

ID=8100053

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69930123T Expired - Fee Related DE69930123T2 (de) 1998-07-01 1999-06-30 Zielgerichtete integration in chromosomen mittels retroviraler vektoren

Country Status (7)

Country Link
US (1) US6656727B2 (de)
EP (1) EP1092035B1 (de)
JP (1) JP2002519069A (de)
AT (1) ATE318922T1 (de)
AU (1) AU4903099A (de)
DE (1) DE69930123T2 (de)
WO (1) WO2000001835A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040235173A1 (en) * 2000-07-03 2004-11-25 Gala Design, Inc. Production of host cells containing multiple integrating vectors by serial transduction
CA2413156C (en) * 2000-07-03 2009-08-18 Gala Design, Inc. Expression vectors
US20030224415A1 (en) * 2001-06-29 2003-12-04 Gala Design, Inc. Selection free growth of host cells containing multiple integrating vectors
AU2001271614B2 (en) * 2000-07-03 2007-05-31 Catalent Pharma Solutions, Llc Host cells containing multiple integrating vectors
US7384738B2 (en) * 2002-03-28 2008-06-10 Bremel Robert D Retrovirus-based genomic screening
US20040038304A1 (en) * 2002-03-28 2004-02-26 Gala Design, Inc. Antibody libraries
US20050221429A1 (en) * 2004-01-16 2005-10-06 Cardinal Health Pts, Llc Host cells containing multiple integrating vectors comprising an amplifiable marker
US20060233757A1 (en) * 2004-08-27 2006-10-19 Wendy Maury Vectors with viral insulators
ES2653843T3 (es) 2004-09-02 2018-02-09 Wyeth Llc Sistemas y procedimientos de producción de proteínas
WO2006078431A2 (en) * 2004-12-22 2006-07-27 The University Of Iowa Research Foundation Compositions and methods related to modified retroviral vectors for restricted, site specific integration

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856152A (en) 1994-10-28 1999-01-05 The Trustees Of The University Of Pennsylvania Hybrid adenovirus-AAV vector and methods of use therefor
US5650309A (en) 1995-05-16 1997-07-22 The Regents Of The University Of California Viral vectors
US5801030A (en) * 1995-09-01 1998-09-01 Genvec, Inc. Methods and vectors for site-specific recombination
EP1005561A4 (de) * 1997-03-21 2004-03-31 Enzo Therapeutics Inc A Fully Vektor, virale vektoren und verpackungszelllinien zur deren vermehrung
US6251677B1 (en) * 1997-08-25 2001-06-26 The Trustees Of The University Of Pennsylvania Hybrid adenovirus-AAV virus and methods of use thereof

Also Published As

Publication number Publication date
JP2002519069A (ja) 2002-07-02
AU4903099A (en) 2000-01-24
ATE318922T1 (de) 2006-03-15
EP1092035B1 (de) 2006-03-01
WO2000001835A2 (en) 2000-01-13
DE69930123T2 (de) 2006-10-12
WO2000001835A3 (en) 2000-04-06
US6656727B2 (en) 2003-12-02
EP1092035A2 (de) 2001-04-18
US20010043921A1 (en) 2001-11-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee