DE69927983D1 - Verfahren zur isotopentrennung und isotopenanreicherung in der gasphase - Google Patents
Verfahren zur isotopentrennung und isotopenanreicherung in der gasphaseInfo
- Publication number
- DE69927983D1 DE69927983D1 DE69927983T DE69927983T DE69927983D1 DE 69927983 D1 DE69927983 D1 DE 69927983D1 DE 69927983 T DE69927983 T DE 69927983T DE 69927983 T DE69927983 T DE 69927983T DE 69927983 D1 DE69927983 D1 DE 69927983D1
- Authority
- DE
- Germany
- Prior art keywords
- ions
- gas
- analyzer region
- isotope
- dimensional space
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
- G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D59/00—Separation of different isotopes of the same chemical element
- B01D59/44—Separation by mass spectrography
- B01D59/46—Separation by mass spectrography using only electrostatic fields
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D59/00—Separation of different isotopes of the same chemical element
- B01D59/44—Separation by mass spectrography
- B01D59/48—Separation by mass spectrography using electrostatic and magnetic fields
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
- H01J49/044—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for preventing droplets from entering the analyzer; Desolvation of droplets
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Electrochemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Inorganic Insulating Materials (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9548198P | 1998-08-05 | 1998-08-05 | |
US95481P | 1998-08-05 | ||
CA2260572 | 1999-01-29 | ||
CA002260572A CA2260572A1 (en) | 1998-08-05 | 1999-01-29 | Apparatus and method for atmospheric pressure 3-dimensional ion trapping |
US09/321,820 US6504149B2 (en) | 1998-08-05 | 1999-05-28 | Apparatus and method for desolvating and focussing ions for introduction into a mass spectrometer |
US321820 | 1999-05-28 | ||
PCT/CA1999/000716 WO2000008456A1 (en) | 1998-08-05 | 1999-08-05 | Method for separation and enrichment of isotopes in gaseous phase |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69927983D1 true DE69927983D1 (de) | 2005-12-01 |
DE69927983T2 DE69927983T2 (de) | 2006-08-24 |
Family
ID=42298131
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69927983T Expired - Lifetime DE69927983T2 (de) | 1998-08-05 | 1999-08-05 | Verfahren zur trennung und anreicherung von isotopen in der gasphase |
DE69928111T Expired - Lifetime DE69928111T2 (de) | 1998-08-05 | 1999-08-05 | Vorrichtung und verfahren zur dreidimensionalen ionenspeicherung unter atmosphärendruck |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69928111T Expired - Lifetime DE69928111T2 (de) | 1998-08-05 | 1999-08-05 | Vorrichtung und verfahren zur dreidimensionalen ionenspeicherung unter atmosphärendruck |
Country Status (6)
Country | Link |
---|---|
EP (3) | EP1102984A1 (de) |
JP (2) | JP2002522873A (de) |
AT (2) | ATE308751T1 (de) |
AU (4) | AU5143999A (de) |
DE (2) | DE69927983T2 (de) |
WO (4) | WO2000008455A1 (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6498342B1 (en) * | 1997-06-02 | 2002-12-24 | Advanced Research & Technology Institute | Ion separation instrument |
AU3952200A (en) * | 1999-04-16 | 2000-11-02 | Mds Inc. | Mass spectrometer, including coupling of an atmospheric pressure ion source to alow pressure mass analyzer |
US7098449B1 (en) | 1999-07-21 | 2006-08-29 | The Charles Stark Draper Laboratory, Inc. | Spectrometer chip assembly |
US7399958B2 (en) | 1999-07-21 | 2008-07-15 | Sionex Corporation | Method and apparatus for enhanced ion mobility based sample analysis using various analyzer configurations |
US6495823B1 (en) | 1999-07-21 | 2002-12-17 | The Charles Stark Draper Laboratory, Inc. | Micromachined field asymmetric ion mobility filter and detection system |
US6512224B1 (en) | 1999-07-21 | 2003-01-28 | The Charles Stark Draper Laboratory, Inc. | Longitudinal field driven field asymmetric ion mobility filter and detection system |
US7148477B2 (en) | 1999-07-21 | 2006-12-12 | Sionex Corporation | System for trajectory-based ion species identification |
US7005632B2 (en) | 2002-04-12 | 2006-02-28 | Sionex Corporation | Method and apparatus for control of mobility-based ion species identification |
US6690004B2 (en) | 1999-07-21 | 2004-02-10 | The Charles Stark Draper Laboratory, Inc. | Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry |
US7057168B2 (en) | 1999-07-21 | 2006-06-06 | Sionex Corporation | Systems for differential ion mobility analysis |
US6815669B1 (en) | 1999-07-21 | 2004-11-09 | The Charles Stark Draper Laboratory, Inc. | Longitudinal field driven ion mobility filter and detection system |
US6815668B2 (en) | 1999-07-21 | 2004-11-09 | The Charles Stark Draper Laboratory, Inc. | Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry |
US6806463B2 (en) | 1999-07-21 | 2004-10-19 | The Charles Stark Draper Laboratory, Inc. | Micromachined field asymmetric ion mobility filter and detection system |
US7129482B2 (en) | 1999-07-21 | 2006-10-31 | Sionex Corporation | Explosives detection using differential ion mobility spectrometry |
EP1268041B1 (de) | 2000-02-29 | 2012-09-05 | Ionwerks, Inc. | Verbesserter mobilitäts-spektrometer |
US7164122B2 (en) | 2000-02-29 | 2007-01-16 | Ionwerks, Inc. | Ion mobility spectrometer |
US6822224B2 (en) * | 2000-03-14 | 2004-11-23 | National Research Council Canada | Tandem high field asymmetric waveform ion mobility spectrometry (FAIMS)tandem mass spectrometry |
WO2001069216A2 (en) * | 2000-03-14 | 2001-09-20 | National Research Council Canada | Improved parallel plate geometry faims apparatus and method |
US20030089847A1 (en) * | 2000-03-14 | 2003-05-15 | Roger Guevremont | Tandem high field asymmetric waveform ion mobility spectrometry ( faims)/ion mobility spectrometry |
JP4578613B2 (ja) * | 2000-04-03 | 2010-11-10 | キヤノンアネルバ株式会社 | Qポール型質量分析計 |
US7375319B1 (en) | 2000-06-09 | 2008-05-20 | Willoughby Ross C | Laser desorption ion source |
AU2002257177B2 (en) * | 2001-04-17 | 2004-11-25 | The Charles Stark Draper Laboratory, Inc. | Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry |
US6784424B1 (en) | 2001-05-26 | 2004-08-31 | Ross C Willoughby | Apparatus and method for focusing and selecting ions and charged particles at or near atmospheric pressure |
DE10125907A1 (de) * | 2001-05-28 | 2002-12-12 | Michael Karas | Separation von chiralen Substanzen in einem Ionenmobilitätsspektrometer durch Zuführung selektiv wechselwirkender Kollisionsgase |
US7586088B2 (en) | 2001-06-21 | 2009-09-08 | Micromass Uk Limited | Mass spectrometer and method of mass spectrometry |
CA2391060C (en) * | 2001-06-21 | 2011-08-09 | Micromass Limited | Mass spectrometer |
US7119328B2 (en) | 2001-06-30 | 2006-10-10 | Sionex Corporation | System for DMS peak resolution |
ATE553372T1 (de) | 2001-06-30 | 2012-04-15 | Dh Technologies Dev Pte Ltd | System zum sammeln von daten und zur identifizierung unbekannter substanzen in einem elektrischen feld |
US7091481B2 (en) | 2001-08-08 | 2006-08-15 | Sionex Corporation | Method and apparatus for plasma generation |
US7274015B2 (en) | 2001-08-08 | 2007-09-25 | Sionex Corporation | Capacitive discharge plasma ion source |
US6727496B2 (en) | 2001-08-14 | 2004-04-27 | Sionex Corporation | Pancake spectrometer |
US6998608B2 (en) * | 2002-02-08 | 2006-02-14 | Ionalytics Corporation | FAIMS with non-destructive detection of selectively transmitted ions |
US7034286B2 (en) | 2002-02-08 | 2006-04-25 | Ionalytics Corporation | FAIMS apparatus having plural ion inlets and method therefore |
US7122794B1 (en) | 2002-02-21 | 2006-10-17 | Sionex Corporation | Systems and methods for ion mobility control |
US6624410B1 (en) * | 2002-02-25 | 2003-09-23 | Monitor Instruments Company, Llc | Cycloidal mass spectrometer |
US6906319B2 (en) | 2002-05-17 | 2005-06-14 | Micromass Uk Limited | Mass spectrometer |
US7095019B1 (en) | 2003-05-30 | 2006-08-22 | Chem-Space Associates, Inc. | Remote reagent chemical ionization source |
US6831273B2 (en) * | 2002-07-31 | 2004-12-14 | General Electric Company | Ion mobility spectrometers with improved resolution |
US7309861B2 (en) | 2002-09-03 | 2007-12-18 | Micromass Uk Limited | Mass spectrometer |
AU2003298597A1 (en) | 2002-10-12 | 2004-05-25 | Sionex Corporation | NOx MONITOR USING DIFFERENTIAL MOBILITY SPECTROMETRY |
CA2521099A1 (en) * | 2003-04-09 | 2004-10-28 | Brigham Young University | Cross-flow ion mobility analyzer |
WO2004114347A2 (en) * | 2003-06-20 | 2004-12-29 | Brigham Young University | Single device for ion mobility and ion trap mass spectrometry |
US7223970B2 (en) | 2003-09-17 | 2007-05-29 | Sionex Corporation | Solid-state gas flow generator and related systems, applications, and methods |
US7227134B2 (en) | 2003-11-25 | 2007-06-05 | Sionex Corporation | Mobility based apparatus and methods using dispersion characteristics, sample fragmentation, and/or pressure control to improve analysis of a sample |
WO2005060696A2 (en) | 2003-12-18 | 2005-07-07 | Sionex Corporation | Methods and apparatus for enhanced ion based sample detection using selective pre-separation and amplification |
WO2005074584A2 (en) | 2004-02-02 | 2005-08-18 | Sionex Corporation | Compact sample analysis systems and related methods using combined chromatography and mobility spectrometry techniques |
WO2005106450A1 (en) | 2004-04-28 | 2005-11-10 | Sionex Corporation | System and method for ion species analysis with enhanced condition control and data interpretation using differential mobility spectrometers |
GB0424426D0 (en) | 2004-11-04 | 2004-12-08 | Micromass Ltd | Mass spectrometer |
US7399959B2 (en) | 2004-12-03 | 2008-07-15 | Sionex Corporation | Method and apparatus for enhanced ion based sample filtering and detection |
EP1920243B1 (de) | 2005-04-29 | 2015-09-09 | DH Technologies Development Pte. Ltd. | Kompakte auf gaschromatographie und ionenmobilität basierende probenanalysesysteme, -verfahren und -vorrichtungen |
US7351960B2 (en) | 2005-05-16 | 2008-04-01 | Thermo Finnigan Llc | Enhanced ion desolvation for an ion mobility spectrometry device |
WO2007034239A2 (en) * | 2005-09-19 | 2007-03-29 | Owlstone Ltd | Ion pump |
GB0522933D0 (en) | 2005-11-10 | 2005-12-21 | Micromass Ltd | Mass spectrometer |
JP2007220488A (ja) * | 2006-02-16 | 2007-08-30 | Tokyo Gas Co Ltd | プラズマ放電装置および排気ガス処理装置 |
US7339166B2 (en) | 2006-02-24 | 2008-03-04 | Battelle Memorial Institute | Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure |
CA2650240C (en) | 2006-04-20 | 2016-01-19 | Axel Mie | Method for separation of molecules |
US8217344B2 (en) | 2007-02-01 | 2012-07-10 | Dh Technologies Development Pte. Ltd. | Differential mobility spectrometer pre-filter assembly for a mass spectrometer |
JP4905270B2 (ja) * | 2007-06-29 | 2012-03-28 | 株式会社日立製作所 | イオントラップ、質量分析計、イオンモビリティ分析計 |
US8173959B1 (en) | 2007-07-21 | 2012-05-08 | Implant Sciences Corporation | Real-time trace detection by high field and low field ion mobility and mass spectrometry |
JP5323384B2 (ja) * | 2008-04-14 | 2013-10-23 | 株式会社日立製作所 | 質量分析計および質量分析方法 |
JP5579706B2 (ja) * | 2008-05-30 | 2014-08-27 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 差動移動度分光計用のカーテンガスに調整剤を提供するための方法およびシステム |
JP5767581B2 (ja) * | 2008-05-30 | 2015-08-19 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 調整可能な選択性および分解能を有する真空駆動微分型移動度分析計/質量分析計のための方法およびシステム |
US8237118B2 (en) | 2008-08-21 | 2012-08-07 | University Of Florida Research Foundation, Inc. | Partial ovoidal FAIMS electrode |
US9330896B2 (en) | 2012-09-25 | 2016-05-03 | Yoshinori Sano | Mass analysis device and mass separation device |
GB2549248B (en) | 2016-01-12 | 2020-07-22 | Thermo Fisher Scient Bremen Gmbh | IRMS sample introduction system and method |
JP6330154B2 (ja) * | 2016-05-24 | 2018-05-30 | パナソニックIpマネジメント株式会社 | 電界非対称性イオン移動度分光計、およびそれを用いた混合物分離方法 |
CN108899264B (zh) * | 2018-06-07 | 2020-01-31 | 中国科学院合肥物质科学研究院 | 一种高灵敏高场不对称波形离子迁移谱检测装置 |
GB201810273D0 (en) | 2018-06-22 | 2018-08-08 | Thermo Fisher Scient Bremen Gmbh | Structural analysis of ionised molecules |
US11092569B1 (en) | 2020-07-05 | 2021-08-17 | Cannabix Technologies Inc. | Apparatus and methods for detection of molecules |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5521380A (en) * | 1992-05-29 | 1996-05-28 | Wells; Gregory J. | Frequency modulated selected ion species isolation in a quadrupole ion trap |
US5420424A (en) * | 1994-04-29 | 1995-05-30 | Mine Safety Appliances Company | Ion mobility spectrometer |
US5729014A (en) * | 1996-07-11 | 1998-03-17 | Varian Associates, Inc. | Method for injection of externally produced ions into a quadrupole ion trap |
JP3386048B2 (ja) * | 2000-12-14 | 2003-03-10 | 株式会社島津製作所 | イオントラップ型質量分析装置 |
-
1999
- 1999-08-05 EP EP99936208A patent/EP1102984A1/de not_active Ceased
- 1999-08-05 WO PCT/CA1999/000715 patent/WO2000008455A1/en active Application Filing
- 1999-08-05 EP EP99936212A patent/EP1102986B8/de not_active Expired - Lifetime
- 1999-08-05 AT AT99936212T patent/ATE308751T1/de not_active IP Right Cessation
- 1999-08-05 WO PCT/CA1999/000718 patent/WO2000008457A1/en active IP Right Grant
- 1999-08-05 AT AT99936210T patent/ATE308043T1/de not_active IP Right Cessation
- 1999-08-05 AU AU51439/99A patent/AU5143999A/en not_active Abandoned
- 1999-08-05 JP JP2000564041A patent/JP2002522873A/ja active Pending
- 1999-08-05 DE DE69927983T patent/DE69927983T2/de not_active Expired - Lifetime
- 1999-08-05 AU AU51440/99A patent/AU5144099A/en not_active Abandoned
- 1999-08-05 AU AU51441/99A patent/AU5144199A/en not_active Abandoned
- 1999-08-05 WO PCT/CA1999/000714 patent/WO2000008454A1/en not_active Application Discontinuation
- 1999-08-05 AU AU51443/99A patent/AU5144399A/en not_active Abandoned
- 1999-08-05 WO PCT/CA1999/000716 patent/WO2000008456A1/en active IP Right Grant
- 1999-08-05 DE DE69928111T patent/DE69928111T2/de not_active Expired - Lifetime
- 1999-08-05 EP EP99936210A patent/EP1102985B8/de not_active Expired - Lifetime
-
2009
- 2009-12-21 JP JP2009289543A patent/JP4990348B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4990348B2 (ja) | 2012-08-01 |
EP1102986A1 (de) | 2001-05-30 |
AU5144099A (en) | 2000-02-28 |
EP1102984A1 (de) | 2001-05-30 |
EP1102986B8 (de) | 2006-01-11 |
DE69928111T2 (de) | 2006-07-27 |
JP2010108941A (ja) | 2010-05-13 |
EP1102986B1 (de) | 2005-11-02 |
WO2000008456A1 (en) | 2000-02-17 |
WO2000008455A1 (en) | 2000-02-17 |
ATE308751T1 (de) | 2005-11-15 |
AU5143999A (en) | 2000-02-28 |
WO2000008457A1 (en) | 2000-02-17 |
AU5144199A (en) | 2000-02-28 |
AU5144399A (en) | 2000-02-28 |
EP1102985B8 (de) | 2006-04-26 |
DE69928111D1 (de) | 2005-12-08 |
ATE308043T1 (de) | 2005-11-15 |
WO2000008454A1 (en) | 2000-02-17 |
JP2002522873A (ja) | 2002-07-23 |
EP1102985A1 (de) | 2001-05-30 |
DE69927983T2 (de) | 2006-08-24 |
EP1102985B1 (de) | 2005-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: NATIONAL RESEARCH COUNCIL CANADA, OTTAWA, ONTARIO, |
|
8332 | No legal effect for de | ||
8370 | Indication related to discontinuation of the patent is to be deleted | ||
8364 | No opposition during term of opposition |