DE69927568T2 - Radioaktive markierte peptide für die diagnose und therapie von brust- und prostatatumoren und von metastasen dieser tumore - Google Patents
Radioaktive markierte peptide für die diagnose und therapie von brust- und prostatatumoren und von metastasen dieser tumore Download PDFInfo
- Publication number
- DE69927568T2 DE69927568T2 DE69927568T DE69927568T DE69927568T2 DE 69927568 T2 DE69927568 T2 DE 69927568T2 DE 69927568 T DE69927568 T DE 69927568T DE 69927568 T DE69927568 T DE 69927568T DE 69927568 T2 DE69927568 T2 DE 69927568T2
- Authority
- DE
- Germany
- Prior art keywords
- tumors
- breast
- metastases
- diagnosis
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000481 breast Anatomy 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 2
- 206010027476 Metastases Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 210000002307 prostate Anatomy 0.000 title 1
- 230000002285 radioactive effect Effects 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 102000004862 Gastrin releasing peptide Human genes 0.000 abstract 2
- 108090001053 Gastrin releasing peptide Proteins 0.000 abstract 2
- PUBCCFNQJQKCNC-XKNFJVFFSA-N gastrin-releasingpeptide Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(C)C)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)O)C(C)C)C1=CNC=N1 PUBCCFNQJQKCNC-XKNFJVFFSA-N 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 239000000816 peptidomimetic Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8807498P | 1998-06-05 | 1998-06-05 | |
| US8851798P | 1998-06-08 | 1998-06-08 | |
| PCT/US1999/012414 WO1999062563A2 (en) | 1998-06-05 | 1999-06-03 | Radiolabeled peptides for the diagnosis and treatment of breast and prostate tumors and metastases of such tumors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69927568D1 DE69927568D1 (de) | 2006-02-16 |
| DE69927568T2 true DE69927568T2 (de) | 2006-06-14 |
Family
ID=26778250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69927568T Expired - Lifetime DE69927568T2 (de) | 1998-06-05 | 1999-06-03 | Radioaktive markierte peptide für die diagnose und therapie von brust- und prostatatumoren und von metastasen dieser tumore |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1001977B1 (https=) |
| JP (1) | JP4295921B2 (https=) |
| AT (1) | ATE305940T1 (https=) |
| CA (1) | CA2299389A1 (https=) |
| DE (1) | DE69927568T2 (https=) |
| DK (1) | DK1001977T3 (https=) |
| ES (1) | ES2247835T3 (https=) |
| WO (1) | WO1999062563A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6869591B2 (en) * | 2002-03-26 | 2005-03-22 | Barnes-Jewish Hospital | Paramagnetic particles that provide improved relaxivity |
| US8420050B2 (en) | 2003-01-13 | 2013-04-16 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7850947B2 (en) | 2003-01-13 | 2010-12-14 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7226577B2 (en) * | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
| US7922998B2 (en) | 2003-01-13 | 2011-04-12 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7611692B2 (en) | 2003-01-13 | 2009-11-03 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| JP5099919B2 (ja) * | 2005-11-29 | 2012-12-19 | マリンクロッド インコーポレイテッド | 二官能性金属キレートコンジュゲート |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750646A (en) * | 1987-09-24 | 1998-05-12 | The Administrators Of The Tulane Educational Fund | Bradykinin analogs with non-peptide bond |
| ES2070329T3 (es) * | 1989-07-20 | 1995-06-01 | Sandoz Ltd | Derivados de polipeptidos. |
-
1999
- 1999-06-03 WO PCT/US1999/012414 patent/WO1999062563A2/en not_active Ceased
- 1999-06-03 DK DK99955223T patent/DK1001977T3/da active
- 1999-06-03 ES ES99955223T patent/ES2247835T3/es not_active Expired - Lifetime
- 1999-06-03 DE DE69927568T patent/DE69927568T2/de not_active Expired - Lifetime
- 1999-06-03 JP JP2000551817A patent/JP4295921B2/ja not_active Expired - Fee Related
- 1999-06-03 EP EP99955223A patent/EP1001977B1/en not_active Expired - Lifetime
- 1999-06-03 CA CA002299389A patent/CA2299389A1/en not_active Abandoned
- 1999-06-03 AT AT99955223T patent/ATE305940T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE305940T1 (de) | 2005-10-15 |
| EP1001977B1 (en) | 2005-10-05 |
| JP4295921B2 (ja) | 2009-07-15 |
| DK1001977T3 (da) | 2005-12-27 |
| EP1001977A2 (en) | 2000-05-24 |
| WO1999062563A2 (en) | 1999-12-09 |
| JP2002516882A (ja) | 2002-06-11 |
| DE69927568D1 (de) | 2006-02-16 |
| ES2247835T3 (es) | 2006-03-01 |
| WO1999062563A3 (en) | 2000-02-10 |
| CA2299389A1 (en) | 1999-12-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |