DE69923838D1 - Stereoisomere von propyl-isopropylacetamid, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zubereitungen - Google Patents

Stereoisomere von propyl-isopropylacetamid, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zubereitungen

Info

Publication number
DE69923838D1
DE69923838D1 DE69923838T DE69923838T DE69923838D1 DE 69923838 D1 DE69923838 D1 DE 69923838D1 DE 69923838 T DE69923838 T DE 69923838T DE 69923838 T DE69923838 T DE 69923838T DE 69923838 D1 DE69923838 D1 DE 69923838D1
Authority
DE
Germany
Prior art keywords
group
ethyl
stereoisomers
methyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69923838T
Other languages
English (en)
Other versions
DE69923838T2 (de
Inventor
Meir Bialer
Boris Yagen
Ofer Spigelstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Application granted granted Critical
Publication of DE69923838D1 publication Critical patent/DE69923838D1/de
Publication of DE69923838T2 publication Critical patent/DE69923838T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69923838T 1998-04-16 1999-04-12 Stereoisomere von propyl-isopropylacetamid, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zubereitungen Expired - Lifetime DE69923838T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL12411898 1998-04-16
IL124118A IL124118A (en) 1998-04-16 1998-04-16 Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, method for their synthesis and pharmaceutical compositions containing them
PCT/IL1999/000197 WO1999054282A1 (en) 1998-04-16 1999-04-12 Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, a method for their synthesis and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DE69923838D1 true DE69923838D1 (de) 2005-03-31
DE69923838T2 DE69923838T2 (de) 2006-04-06

Family

ID=11071421

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69923838T Expired - Lifetime DE69923838T2 (de) 1998-04-16 1999-04-12 Stereoisomere von propyl-isopropylacetamid, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zubereitungen

Country Status (8)

Country Link
US (1) US6630602B1 (de)
EP (1) EP1077926B1 (de)
AT (1) ATE289583T1 (de)
AU (1) AU3342899A (de)
DE (1) DE69923838T2 (de)
ES (1) ES2238831T3 (de)
IL (2) IL124118A (de)
WO (1) WO1999054282A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL147953A (en) * 2002-02-01 2008-04-13 Meir Bialer Derivatives and pharmaceutical compositions of n-hydroxymethyl tetramethylcyclopropyl-
IL157751A0 (en) * 2003-02-28 2004-03-28 Yissum Res Dev Co New amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid, a method for their synthesis and pharmaceutical compositions containing them
US20060004098A1 (en) 2003-07-28 2006-01-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compounds useful for treating neurological disorders
WO2006012603A2 (en) * 2004-07-22 2006-02-02 Nps Pharmaceuticals, Inc. Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
JP2008526894A (ja) * 2005-01-10 2008-07-24 レジェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア Ｃｏｘ阻害剤および５−ｌｏｘ阻害剤の活性を助けるための可溶性エポキシドヒドロラーゼの阻害剤の使用
JP2009504785A (ja) * 2005-08-19 2009-02-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 鎮痛剤としてのｓＥＨ阻害剤の使用
WO2008073130A1 (en) * 2006-12-15 2008-06-19 Regents Of The University Of California Use of cis-epoxyeicosatrienoic acids and inhibitors of soluble epoxide hydrolase to treat conditions mediated by pbr, cb2, and nk2 receptors
AR067533A1 (es) * 2007-07-16 2009-10-14 Wyeth Corp Procesos e inetermediarios para la preparacion de compuestos de sulfonamida heterociclica
EP2219450A4 (de) * 2007-11-08 2012-01-25 Univ California Linderung neuropathischer schmerzen mit eets- und seh-inhibitoren
US10813894B2 (en) 2015-02-20 2020-10-27 The Regents Of The University Of California Methods of inhibiting pain

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4231085A1 (de) * 1992-09-12 1994-03-17 Desitin Arzneimittel Gmbh VPA-analoge Antiepileptika
ATE163006T1 (de) * 1993-06-01 1998-02-15 Ono Pharmaceutical Co Pentansäurederivate
IL120006A (en) * 1997-01-14 2000-12-06 Yissum Res Dev Co Valnoctamide stereoisomers and a method for their synthesis and separation

Also Published As

Publication number Publication date
DE69923838T2 (de) 2006-04-06
AU3342899A (en) 1999-11-08
IL136030A0 (en) 2001-05-20
ATE289583T1 (de) 2005-03-15
EP1077926A1 (de) 2001-02-28
WO1999054282A1 (en) 1999-10-28
IL124118A (en) 2007-09-20
ES2238831T3 (es) 2005-09-01
EP1077926B1 (de) 2005-02-23
US6630602B1 (en) 2003-10-07

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