DE69917609D1 - Arzneimittel und deren verwendung - Google Patents

Arzneimittel und deren verwendung

Info

Publication number
DE69917609D1
DE69917609D1 DE69917609T DE69917609T DE69917609D1 DE 69917609 D1 DE69917609 D1 DE 69917609D1 DE 69917609 T DE69917609 T DE 69917609T DE 69917609 T DE69917609 T DE 69917609T DE 69917609 D1 DE69917609 D1 DE 69917609D1
Authority
DE
Germany
Prior art keywords
medicinal products
composition
micelle
delivering
provides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69917609T
Other languages
English (en)
Other versions
DE69917609T2 (de
Inventor
Steven Leigh
Mathew Louis Steven Leigh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phares Pharmaceutical Research NV
Original Assignee
Phares Pharmaceutical Research NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9804705.3A external-priority patent/GB9804705D0/en
Application filed by Phares Pharmaceutical Research NV filed Critical Phares Pharmaceutical Research NV
Publication of DE69917609D1 publication Critical patent/DE69917609D1/de
Application granted granted Critical
Publication of DE69917609T2 publication Critical patent/DE69917609T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69917609T 1998-03-05 1999-03-05 Arzneimittel und deren verwendung Expired - Fee Related DE69917609T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9804705 1998-03-05
GBGB9804705.3A GB9804705D0 (en) 1998-03-05 1998-03-05 Pharmaceutical compositions and their use
GBGB9827835.1A GB9827835D0 (en) 1998-03-05 1998-12-17 Pharmaceutical compositions and their use
GB9827835 1998-12-17
PCT/GB1999/000656 WO1999044642A1 (en) 1998-03-05 1999-03-05 Pharmaceutical compositions and their use

Publications (2)

Publication Number Publication Date
DE69917609D1 true DE69917609D1 (de) 2004-07-01
DE69917609T2 DE69917609T2 (de) 2005-06-09

Family

ID=26313227

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69917609T Expired - Fee Related DE69917609T2 (de) 1998-03-05 1999-03-05 Arzneimittel und deren verwendung

Country Status (7)

Country Link
US (1) US6605298B1 (de)
EP (1) EP1059941B1 (de)
JP (1) JP2002505307A (de)
AT (1) ATE267613T1 (de)
AU (1) AU2845599A (de)
DE (1) DE69917609T2 (de)
WO (1) WO1999044642A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9908309D0 (en) * 1999-04-12 1999-06-02 Phares Pharm Res Nv Lipid aggregate forming compositions and their use
WO2001028518A1 (de) * 1999-10-20 2001-04-26 Vesifact Ag Cyclosporine enthaltende mikroemulsion-prekonzentrate und mikroemulsionen
DE10026699A1 (de) * 2000-05-30 2001-12-06 Basf Ag Formulierung auf Heparin-, Glycosaminoglycan- oder Heparinoidbasis und Verwendung der Formulierung sowie der Formulierungsgrundlage
JP2004536089A (ja) * 2001-06-26 2004-12-02 イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム 物質を細胞内に導入するための配合物及び方法
WO2003088949A2 (de) * 2002-04-19 2003-10-30 Bioghurt Biogarde Gmbh & Co. Kg. Matrix mit einer bioaktiven phospholipid-haltigen komponente
US7306819B2 (en) 2002-06-12 2007-12-11 The Coca-Cola Company Beverages containing plant sterols
US7335389B2 (en) 2002-06-12 2008-02-26 The Coca-Cola Company Beverages containing plant sterols
RU2006138703A (ru) * 2004-05-06 2008-06-20 Эмисфире Текнолоджис Твердая лекарственная форма увлажненного гепарина
US8273794B2 (en) 2004-05-14 2012-09-25 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
WO2005110360A2 (en) * 2004-05-18 2005-11-24 Phares Pharmaceutical Research N.V. Compositions for injection
US20080171687A1 (en) * 2004-09-16 2008-07-17 Abraxis Bioscience, Inc. Compositions And Methods For The Preparation And Administration Of Poorly Water Soluble Drugs
EP2067475A4 (de) 2006-09-26 2010-12-15 Astellas Pharma Inc Tacrolimus-zubereitung mit verzögerter freisetzung
WO2008084698A1 (ja) 2006-12-28 2008-07-17 Astellas Pharma Inc. タクロリムス徐放性医薬組成物
JP2010539245A (ja) 2007-09-14 2010-12-16 日東電工株式会社 薬物担体
US20100086504A1 (en) * 2008-07-23 2010-04-08 Gregor Cevc Methods of administering topical antifungal formulations for the treatment of fungal infections
EP2151231B1 (de) * 2008-08-05 2017-08-02 PM-International AG Kosmetische Formulierung
DK2365802T3 (da) 2008-11-11 2017-11-13 Univ Texas Mikrokapsler af rapamycin og anvendelse til behandling af cancer
EP2387391B1 (de) * 2009-07-24 2017-01-11 MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH Verfahren zur entwicklung einer als schaum auf die haut zu applizierenden flüssigen zusammensetzung sowie eine topisch applizierbare zusammensetzung
US9283211B1 (en) 2009-11-11 2016-03-15 Rapamycin Holdings, Llc Oral rapamycin preparation and use for stomatitis
US9314509B2 (en) 2009-11-16 2016-04-19 Ipsen Pharma S.A.S. Pharmaceutical compositions of melanocortin receptor ligands
EP2518040B1 (de) * 2009-12-25 2018-10-31 Farnex Incorporated Flüssigkristallverbindung von geringer viskosität
TWI438009B (zh) * 2010-02-19 2014-05-21 Teikoku Pharma Usa Inc 紫杉烷前－乳劑調配物及其製造與使用之方法
MX343499B (es) * 2010-03-15 2016-11-08 Ipsen Pharma Sas Composiciones farmaceuticas de ligandos receptores de secretagoga de la hormona de crecimiento.
SG185389A1 (en) 2010-05-03 2012-12-28 Teikoku Pharma Usa Inc Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
DK2968281T3 (da) 2013-03-13 2020-11-02 Univ Texas Mtor-hæmmere til forebyggelse af vækst af tarmpolyp
US9700544B2 (en) 2013-12-31 2017-07-11 Neal K Vail Oral rapamycin nanoparticle preparations
CA2933908C (en) 2013-12-31 2024-01-30 Rapamycin Holdings, Llc Oral rapamycin nanoparticle preparations and use
US10588866B2 (en) 2014-11-11 2020-03-17 Verdure Sciences Stable solid lipid particle composition for improved bioavailability of lipophilic compounds for age-related diseases
CN104473914B (zh) * 2015-01-06 2017-01-11 天津红日药业股份有限公司 一种磺酰胺类药物组合物
KR101905010B1 (ko) 2016-04-19 2018-10-08 앱티스 주식회사 코엔자임 q10 가용화 조성물 및 이의 제조방법
US11571385B2 (en) 2017-05-18 2023-02-07 Kewpie Corporation Self-emulsifiable composition, production method therefor, nanoemulsion, and production method therefor
US10716774B1 (en) * 2018-01-05 2020-07-21 Yale Pharmaceuticals LLC Pharmaceutical compositions containing isotretinoin with improved dissolution profile and enhanced stability

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB505983A (en) * 1937-11-17 1939-05-17 Ig Farbenindustrie Ag Improvements in the manufacture and production of pharmaceutically active substances
FR2374910A1 (fr) * 1976-10-23 1978-07-21 Choay Sa Preparation a base d'heparine, comprenant des liposomes, procede pour l'obtenir et medicaments contenant de telles preparations
US5141674A (en) * 1984-03-08 1992-08-25 Phares Pharmaceutical Research N.V. Methods of preparing pro-liposome dispersions and aerosols
EP0158441B2 (de) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposombildende Zusammensetzung
DE3613799C1 (de) 1986-04-24 1987-09-03 Nattermann A & Cie Verwendung von Glycofurol zum Verfluessigen von Arzneimittelzubereitungen fuer das Abfuellen in Weichgelatinekapseln
US5009956A (en) * 1987-02-24 1991-04-23 Univ Minnesota Phospholipase A2-resistant liposomes
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5043164A (en) * 1989-01-17 1991-08-27 The University Of Tennessee Research Corporation Blood-stable, cholesterol-free liposomes
GB9108043D0 (en) 1991-04-16 1991-06-05 Phares Pharm Res Nv Method for the formation of liposomes and compositions for use therein
DE19609538A1 (de) * 1996-03-11 1997-09-18 Basf Ag Feinverteilte Carotinoid- und Retinoidsuspensionen und Verfahren zu ihrer Herstellung
AU6833994A (en) * 1993-05-17 1994-12-12 Liposome Company, Inc., The Incorporation of taxol into liposomes and gels
GB2315216B (en) 1993-10-05 1998-10-14 Ciba Geigy Ag Microemulsion preconcentrates comprising FK506 or 33-epi-chloro-33-desoxy-ascomycin
US5707648A (en) * 1993-11-17 1998-01-13 Lds Technologies, Inc. Transparent liquid for encapsulated drug delivery
SE9601677D0 (sv) * 1996-05-02 1996-05-02 Scotia Lipidteknik Ab New use
EP0914159A1 (de) * 1996-07-13 1999-05-12 ratiopharm GmbH Topische phospholipidhaltige aciclovirzubereitung
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery

Also Published As

Publication number Publication date
WO1999044642A1 (en) 1999-09-10
JP2002505307A (ja) 2002-02-19
EP1059941B1 (de) 2004-05-26
US6605298B1 (en) 2003-08-12
ATE267613T1 (de) 2004-06-15
AU2845599A (en) 1999-09-20
EP1059941A1 (de) 2000-12-20
DE69917609T2 (de) 2005-06-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee