DE69915327D1 - Derivate des erythromycins, des clarithromycins, des roxithromycins oder des azithromycin mit antibiotischer und mucolytischer wirkung - Google Patents

Derivate des erythromycins, des clarithromycins, des roxithromycins oder des azithromycin mit antibiotischer und mucolytischer wirkung

Info

Publication number
DE69915327D1
DE69915327D1 DE69915327T DE69915327T DE69915327D1 DE 69915327 D1 DE69915327 D1 DE 69915327D1 DE 69915327 T DE69915327 T DE 69915327T DE 69915327 T DE69915327 T DE 69915327T DE 69915327 D1 DE69915327 D1 DE 69915327D1
Authority
DE
Germany
Prior art keywords
antibiotic
mucolytic
roxithromycin
clarithromycin
azithromycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69915327T
Other languages
English (en)
Other versions
DE69915327T2 (de
Inventor
Helmut Schickaneder
Aggelos Nikolopoulos
Gesine Hermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Russinsky Ltd
Original Assignee
Russinsky Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Russinsky Ltd filed Critical Russinsky Ltd
Application granted granted Critical
Publication of DE69915327D1 publication Critical patent/DE69915327D1/de
Publication of DE69915327T2 publication Critical patent/DE69915327T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69915327T 1998-10-20 1999-10-15 Derivate des erythromycins, des clarithromycins, des roxithromycins oder des azithromycin mit antibiotischer und mucolytischer wirkung Expired - Fee Related DE69915327T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IE980869 1998-10-20
IE980869 1998-10-20
IE981062 1998-12-17
IE981062 1998-12-17
PCT/IE1999/000106 WO2000023081A1 (en) 1998-10-20 1999-10-15 Derivatives of erythromycin, clarithromycin, roxithromycin or azithromycin with antibiotic and mucolytic activity

Publications (2)

Publication Number Publication Date
DE69915327D1 true DE69915327D1 (de) 2004-04-08
DE69915327T2 DE69915327T2 (de) 2005-02-10

Family

ID=26320218

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69915327T Expired - Fee Related DE69915327T2 (de) 1998-10-20 1999-10-15 Derivate des erythromycins, des clarithromycins, des roxithromycins oder des azithromycin mit antibiotischer und mucolytischer wirkung

Country Status (7)

Country Link
US (1) US6599885B2 (de)
EP (1) EP1121134B1 (de)
AT (1) ATE260665T1 (de)
AU (1) AU760884B2 (de)
CA (1) CA2346870A1 (de)
DE (1) DE69915327T2 (de)
WO (1) WO2000023081A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ521368A (en) * 2000-03-28 2004-05-28 Biochemie Ges M Granulated particles of an active compound, with a film-forming coating resulting in the masked taste of said active compound
JP2009500356A (ja) * 2005-07-07 2009-01-08 エラン ファーマ インターナショナル リミテッド ナノ粒子クラリスロマイシン製剤
US20100022652A1 (en) * 2008-07-28 2010-01-28 Tyco Healthcare Group Lp Antimicrobial and Anticoagulant Compositions and Methods
CA2784494C (en) * 2009-12-18 2019-03-12 North-West University Composition comprising an amorphous non-crystalline glass form of roxithromycin
CN104177457A (zh) * 2013-05-23 2014-12-03 长春海悦药业有限公司 一种阿奇霉素药物原料及其制剂和用途
MX2020000265A (es) 2017-07-07 2020-07-22 Epicentrx Inc Composiciones para la administración parenteral de agentes terapéuticos.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2824443A1 (de) 1978-06-03 1979-12-13 Basf Ag Lagerstabile und fliessfaehige silikatsuspensionen
IT1134458B (it) * 1980-11-26 1986-08-13 Real Sas Di Alberto Reiner Derivato della n-acetil-cisteina ad attivita' terapeutica,procedimento per la sua preparazione e relative composizioni farmaceutiche
IT1134457B (it) * 1980-11-26 1986-08-13 Real Sas Di Alberto Reiner Derivato dell'alfa-mercapto propionilglicina ad attivita' terapeutica,procedimento per la sua preparazione e relative composizioni farmaceutiche
FR2502627A1 (fr) 1981-02-02 1982-10-01 Refarmed Sa Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent
FR2519988B1 (fr) * 1982-01-20 1985-06-14 Refarmed Sa Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent
IT1189285B (it) * 1982-05-28 1988-02-04 Nuovo Consor Sanitar Nazionale Sali dell'antibiotico eritromicina e del suo estere propionico con acidi ad attivita' terapeutica coadiuvante
AU4399396A (en) * 1994-12-19 1996-07-10 Russinsky Limited Compounds
ATE201026T1 (de) * 1996-08-07 2001-05-15 Russinsky Ltd Verfahren zur herstellung von salzen von erythromicyn, roxithromicyn, clarythromicyn und azithromycin

Also Published As

Publication number Publication date
EP1121134B1 (de) 2004-03-03
WO2000023081A1 (en) 2000-04-27
CA2346870A1 (en) 2000-04-27
US20010031736A1 (en) 2001-10-18
DE69915327T2 (de) 2005-02-10
AU6118599A (en) 2000-05-08
EP1121134A1 (de) 2001-08-08
AU760884B2 (en) 2003-05-22
US6599885B2 (en) 2003-07-29
ATE260665T1 (de) 2004-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee