DE69913377D1 - Gemischte paroxetin-propan-2-olsolvate - Google Patents

Gemischte paroxetin-propan-2-olsolvate

Info

Publication number
DE69913377D1
DE69913377D1 DE69913377T DE69913377T DE69913377D1 DE 69913377 D1 DE69913377 D1 DE 69913377D1 DE 69913377 T DE69913377 T DE 69913377T DE 69913377 T DE69913377 T DE 69913377T DE 69913377 D1 DE69913377 D1 DE 69913377D1
Authority
DE
Germany
Prior art keywords
mixed
solvate
olsolvate
paroxetin
propane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69913377T
Other languages
English (en)
Other versions
DE69913377T2 (de
Inventor
Andrew Simon Craig
Victor Witold Jacewicz
Neal Ward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9826182.9A external-priority patent/GB9826182D0/en
Priority claimed from GBGB9916257.0A external-priority patent/GB9916257D0/en
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of DE69913377D1 publication Critical patent/DE69913377D1/de
Publication of DE69913377T2 publication Critical patent/DE69913377T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DE69913377T 1998-11-30 1999-11-30 Gemischte Paroxetin-Propan-2-ol-Solvate Expired - Lifetime DE69913377T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9826182.9A GB9826182D0 (en) 1998-11-30 1998-11-30 Novel process
GB9826182 1998-11-30
GBGB9916257.0A GB9916257D0 (en) 1999-07-12 1999-07-12 Novel compounds
GB9916257 1999-07-12
PCT/GB1999/003993 WO2000032594A1 (en) 1998-11-30 1999-11-30 Mixed paroxetine propan-2-ol solvates

Publications (2)

Publication Number Publication Date
DE69913377D1 true DE69913377D1 (de) 2004-01-15
DE69913377T2 DE69913377T2 (de) 2004-12-30

Family

ID=26314751

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69913377T Expired - Lifetime DE69913377T2 (de) 1998-11-30 1999-11-30 Gemischte Paroxetin-Propan-2-ol-Solvate

Country Status (9)

Country Link
EP (2) EP1408039A3 (de)
JP (1) JP2002531452A (de)
AT (1) ATE255577T1 (de)
AU (1) AU1397900A (de)
DE (1) DE69913377T2 (de)
DK (1) DK1135383T3 (de)
ES (1) ES2211232T3 (de)
PT (1) PT1135383E (de)
WO (1) WO2000032594A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1017421C2 (nl) 2001-02-21 2002-01-15 Synthon Bv Werkwijze voor het vervaardigen van paroxetine.
WO2007054978A2 (en) * 2005-11-10 2007-05-18 Jubilant Organosys Limited Process for preparing paroxetine hydrochloride hemihydrate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
EP0223403B1 (de) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel
SK283608B6 (sk) * 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
EP1384711A1 (de) * 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Optische Trennung eines Piperidin-Derivates
HU221921B1 (hu) * 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására

Also Published As

Publication number Publication date
ES2211232T3 (es) 2004-07-01
EP1135383A1 (de) 2001-09-26
AU1397900A (en) 2000-06-19
DK1135383T3 (da) 2004-04-05
DE69913377T2 (de) 2004-12-30
ATE255577T1 (de) 2003-12-15
EP1408039A2 (de) 2004-04-14
JP2002531452A (ja) 2002-09-24
EP1135383B1 (de) 2003-12-03
EP1408039A3 (de) 2004-05-12
PT1135383E (pt) 2004-04-30
WO2000032594A1 (en) 2000-06-08

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