DE69912248D1 - 6,9-disubstituierte 2-[trans-(4-aminocyclohexyl)amino] purine - Google Patents

6,9-disubstituierte 2-[trans-(4-aminocyclohexyl)amino] purine

Info

Publication number
DE69912248D1
DE69912248D1 DE69912248T DE69912248T DE69912248D1 DE 69912248 D1 DE69912248 D1 DE 69912248D1 DE 69912248 T DE69912248 T DE 69912248T DE 69912248 T DE69912248 T DE 69912248T DE 69912248 D1 DE69912248 D1 DE 69912248D1
Authority
DE
Germany
Prior art keywords
aminocyclohexyl
disubstituted
purine
trans
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69912248T
Other languages
English (en)
Other versions
DE69912248T2 (de
Inventor
Jennifer Ann Dumont
Alan Joseph Bitonti
David Roger Borcherding
Norton Paul Peet
Harry Randall Munson
Patrick Wai-Kwok Shum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Priority claimed from PCT/US1999/003450 external-priority patent/WO1999043675A1/en
Application granted granted Critical
Publication of DE69912248D1 publication Critical patent/DE69912248D1/de
Publication of DE69912248T2 publication Critical patent/DE69912248T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69912248T 1998-02-26 1999-02-18 6,9-disubstituierte 2-[trans-(4-aminocyclohexyl)amino] purine Expired - Lifetime DE69912248T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3097598A 1998-02-26 1998-02-26
US30975 1998-02-26
PCT/US1999/003450 WO1999043675A1 (en) 1998-02-26 1999-02-18 6,9-disubstituted 2-[trans-(4- aminocyclohexyl) amino]purines

Publications (2)

Publication Number Publication Date
DE69912248D1 true DE69912248D1 (de) 2003-11-27
DE69912248T2 DE69912248T2 (de) 2004-04-22

Family

ID=21856977

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69912248T Expired - Lifetime DE69912248T2 (de) 1998-02-26 1999-02-18 6,9-disubstituierte 2-[trans-(4-aminocyclohexyl)amino] purine

Country Status (14)

Country Link
KR (1) KR100568657B1 (de)
AR (1) AR018121A1 (de)
AT (1) ATE252583T1 (de)
DE (1) DE69912248T2 (de)
DK (1) DK1056744T3 (de)
ES (1) ES2207182T3 (de)
HK (1) HK1030949A1 (de)
ID (1) ID25444A (de)
NZ (1) NZ506235A (de)
OA (1) OA11455A (de)
PT (1) PT1056744E (de)
RU (1) RU2200162C2 (de)
TW (1) TWI225060B (de)
UA (1) UA66840C2 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091346B1 (en) * 1995-11-01 2006-08-15 Novartis Ag Purine derivatives and processes for their preparation
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques

Also Published As

Publication number Publication date
KR20010041318A (ko) 2001-05-15
ATE252583T1 (de) 2003-11-15
RU2200162C2 (ru) 2003-03-10
KR100568657B1 (ko) 2006-04-07
PT1056744E (pt) 2004-03-31
TWI225060B (en) 2004-12-11
UA66840C2 (uk) 2004-06-15
NZ506235A (en) 2003-02-28
DE69912248T2 (de) 2004-04-22
ID25444A (id) 2000-10-05
ES2207182T3 (es) 2004-05-16
OA11455A (en) 2003-12-05
DK1056744T3 (da) 2004-02-23
HK1030949A1 (en) 2001-05-25
AR018121A1 (es) 2001-10-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC

8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS HOLDINGS INC., GREENVILLE, DEL., US

8327 Change in the person/name/address of the patent owner

Owner name: AVENTISUB II INC., GREENVILLE, DEL., US